成果及论文
（1）Xin Chen#, Ali Momin#, Siyi Wanggou#, Xian Wang, Hyun-Kee Min, Wenkun Dou, Jade Chan, Weifan Dong, Jerry J. Fan, Yi Xiong, Kamilia Talipova, Hongyu Zhao, Yuki X. Chen, Kelly Veerasammy, Adam Fekete, Sachin A. Kumar, Hongwei Liu, Qi Yang,Joe Eun Son, Zhengchao Dou, Malini Hu, Parnian Pardis, Kyle Juraschka, Laura Donovan, Jiao Zhang, Vijay Ramaswamy, Hayden Selvadurai, Peter B. Dirks, Michael D. Taylor, Lu-Yang Wang, Chi-chung Hui, Rinat Abzalimov, Ye He, Yu Sun, Xuejun Li*, and Xi Huang*. Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity. Neuron, 2023, 111: 1-19. (Cover Article)
（2）Xin Chen, Siyi Wanggou, Ankur Bodalia, Min Zhu, Weifan Dong, Jerry J. Fan, Wen Chi Yin, Hyun-Kee Min, Malini Hu, Diana Draghici, Wenkun Dou, Feng Li, Fiona J. Coutinho, Heather Whetstone, Michelle M. Kushida, Peter B. Dirks, Yuanquan Song, Chi-chung Hui, Yu Sun, Lu-Yang Wang, Xuejun Li, and Xi Huang. A feedforward mechanism mediated by mechanosensitive ion channel PIEZO1 and tissue mechanics promotes glioma aggression. Neuron, 2018, 100(4):799-815. (Best of Neuron 2018 and 2019)
（3）Xin Chen, Mei-Yu Ruan, and Shi-Qing Cai. KChIP-like Auxiliary Subunits of Kv4 Channels Regulate Excitability of Muscle Cells and Control Male Turning Behavior during Mating in Caenorhabditis elegans. Journal of Neuroscience, 2015, 35:1880 –1891.
（4） Yi Xiong#, Yihao Zhang#, Na Liu, Yueshuo Li, Hongwei Liu, Qi Yang, Yu Chen, Zhizhi Xia, Xin Chen*, Siyi Wanggou* and Xuejun Li*. Integration of single-cell regulon atlas and multi-omics data for prognostic stratification and personalized treatment prediction in human lung adenocarcinoma. Journal of Translational Medicine, 2023, 25;21(1):499.
（5）Min Zhu, Bin Gu, Evan C Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M Yung, Xin Chen, Kaiwen Zhang, Elizabeth K Woolaver, Mikaela R Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun*, Sevan Hopyan*. A fibronectin gradient remodels mixed-phase mesoderm. Science Advances, 2024, 10(29): eadl6366.
（6）Alexander T Bahcheli#, Hyun-Kee Min#, Masroor Bayati, Hongyu Zhao, Alexander Fortuna, Weifan Dong, Irakli Dzneladze, Jade Chan, Xin Chen, Kissy Guevara-Hoyer, Peter B Dirks, Xi Huang*, Jüri Reimand*. Pan-cancer ion transport signature reveals functional regulators of glioblastoma aggression. The EMBO Journal, 2024, 43(2):196-224.
（7）Meryem B Baghdadi, Ronja M Houtekamer , Louisiane Perrin , Abilasha Rao-Bhatia, Myles Whelen, Linda Decker, Martin Bergert, Carlos Pérez-Gonzàlez, Réda Bouras, Giacomo Gropplero, Adrian K H Loe, Amin Afkhami-Poostchi, Xin Chen, Xi Huang, Stephanie Descroix, Jeffrey L Wrana, Alba Diz-Muñoz, Martijn Gloerich, Arshad Ayyaz, Danijela Matic Vignjevic#, Tae-Hee Kim#. PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance. Science. 2024 Nov 29;386(6725):eadj7615.
（8）Biren M Dave, Xin Chen, Fraser McCready, Connor S Charton, Rachel M Morley, Jignesh K Tailor, James Ellis, Xi Huang, and Peter B Dirks. Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis. Development, 2023, 150(13): dev201534.
（9）Wentian Tang, Xin Chen, Xian Wang, Min Zhu, Guanqiao Shan, Tiancong Wang, Wenkun Dou, Jintian Wang, Juhui Law, Zheyuan Gong, Sevan Hopyan*, Xi Huang*, and Yu Sun*. Indentation Induces Instantaneous Nuclear Stiffening and Unfolding of Nuclear Envelop Wrinkles. Proceedings of the National Academy of Sciences, 2023，120(36):e2307356120.
（10）Wenkun Dou, Abdelkader Daoud, Xin Chen, Tiancong Wang, Manpreet Malhi, Zheyuan Gong, Fatemeh Mirshafiei, Min Zhu, Guanqiao Shan, Xi Huang, Jason T. Maynes*, and Yu Sun*. Ultrathin and flexible bioelectronic arrays for functional measurement of iPSC-cardiomyocytes under cardiotropic drug administration and controlled microenvironments. Nano Letters, 2023, 23(6): 2321-2331.
（11）Xian Wang, Zheyuan Gong, Tiancong Wang, Junhui Law, Xin Chen, Siyi Wanggou, Jintian Wang, Binbin Ying, Michelle Francisco, Weifan Dong, Yi Xiong, Jerry J. Fan, Graham MacLeod, Stephane Angers, Xuejun Li, Peter B. Dirks, Xinyu Liu, Xi Huang*, Yu Sun*. Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes. Science Advances, 2023, 9(13): eade5321.
（12）Weifan Dong, Adam Fekete, Xiaodi Chen, Hongwei Liu, Greg Beilhartz, Xin Chen, ShahrzadBahrampour, Yi Xiong, Qi Yang, Hongyu Zhao, Tian Kong, Malia Morioka, Geena Jung, Ji-EunKim, Daniel Schramek, Peter B. Dirks, Yuanquan Song, Tae-Hee Kim, Ye He, Siyi WanggouXuejun Li, Roman Melnyk, Lu-Yang Wang, Xi Huang. A designer peptide to treat glioblastomaby targeting EAG2-Kvβ2 potassium channel complex-mediated cancer-neuron interaction. Nature Cancer, 2023,4(10):1418-1436.
（13）Xian Wang#, Tiancong Wang#, Xin Chen, Junhui Law, Guanqiao Shan, Wentian Tang, Zheyuan Gong, Peng Pan, Xinyu Liu, Jiangfan Yu, Changhai Ru*, Xi Huang*, and Yu Sun*. Microrobotic Swarms for Intracellular Measurement with Enhanced Signal-to-Noise Ratio. ACS nano, 2022, 16(7): 10824-10839.
（14）Ali Momin#*, Shahrzad Bahrampour#, Hyun-Kee Min#, Xin Chen#, Xian Wang, Yu Sun, and Xi Huang*. Channeling force in the brain: mechanosensitive ion channels choreograph mechanics and malignancies. Trends in Pharmacological Sciences, 2021, 42(5):367-384. (Invited Review, Cover Article)
（15）Michael Pryszlak#, Mallory Wiggans#, Xin Chen, Shyam Patel, Julia Jaramillo, Sarah Burns, Laura Richards, Trevor Pugh, David Kaplan, Xi Huang, Peter Dirks, and Bret J. Pearson. The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells. Cell Reports, 2021, 34(13):1-16.
（16）Zhuoran Zhang, Changsheng Dai, Guanqiao Shan, Xin Chen, Hang Liu, Khaled Abdalla, Iryna Kuznyetsova, Sergey Moskovstev, Xi Huang, Clifford Librach, Keith Jarvi and Yu Sun. Quantitative selection of single human sperm with high DNA integrity for intracytoplasmic sperm injection. Fertility and Sterility, 2021, 116(5):1308-1318.
（17）Michelle A. Francisco, Siyi Wanggou, Jerry J. Fan, Weifan Dong, Xin Chen, Ali Momin, Namal Abeysundara, Hyun-Kee Min, Jade Chan, Rochelle McAdam, Marian Sia, Ronwell J. Pusong, Shixuan Liu, Nish Patel, Vijay Ramaswamy, Xiaochong Wu, Noriyuki Kijima, Lu-Yang Wang, Yuanquan Song, Ran Kafri, Michael D. Taylor, Xuejun Li*, and Xi Huang*. Chloride intracellular channel 1 cooperates with potassium channel to promote medulloblastoma growth. Journal of Experimental Medicine, 2020, 217(5):1-19.
（18）Qiang Jiang#, Kai Li#, Wen-Jing Lu, Shuang Li, Xin Chen, Xi-Juan Liu, Jie Yuan, Qiurong Ding, Feng Lan*, and Shi-Qing Cai*. Identification of small-molecule ion channel modulators in C.elegans channelopathy models. Nature Communications, 2018, 9(1):1-12.
