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成果及论文

近5年主要论文(2017-)

    1. H. Chen, S. Jiang, K. Xu, Z. Ding, J. Wang, M. Cao*, J. Yuan*. Design of Thermoresponsive Genetic Controls with Minimal Heat-Shock Response, ACS Synthetic Biology, 2024, 13: 3032-3040

    2. X. Wei, L. Yang, Z. Chen*, W. Xia, Y. Chen, M. Cao*, N. He*. Molecular weight control of poly-γ-glutamic acid reveals novel insights into extracellular polymeric substance synthesis in Bacillus licheniformis, Biotechnology for Biofuels and Bioproducts, 2024, 17:60

    3. L. Hu, H. Qiu, L. Huang, F. Zhang, V. Tran, J. Yuan, N. He*, M. Cao*. Emerging nonmodel eukaryotes for biofuel production, Current Opinion in Biotechnology, 2023, 84: 103015

    4. Y. Li, Q. Luo, J. Su, G. Dong, M. Cao*, Y. Wang*. Metabolic regulation of Shewanella oneidensis for microbial electrosynthesis: From extracellular to intracellular, Metabolic Engineering, 2023, 80: 1-11

    5. X. Wei, Z. Chen, A. Liu, L. Yang, Y. Xu, M. Cao*, N. He*. Advanced strategies for metabolic engineering of Bacillus to produce extracellular polymeric substances, Biotechnology Advances, 2023, 108199

    6. L. Liu, L. Zhang, J. Wang, M. Cao*, J. Yuan*. Copper-inducible expression system for metabolic engineering of Escherichia coli, Journal of Applied Microbiology, 2023, 134 (6), lxad109

    7. Y. Li, M. Cao*, V. Gupta*, Y. Wang*. Metabolic engineering strategies to enable microbial electrosynthesis utilization of CO2: recent progress and challenges. Critical Reviews in Biotechnology, 2024, 44(3): 352-372

    8. G. Chi, X. Cao, Q. Li, C. Yao, F. Lu, Y. Liu*, M. Cao*, and N. He*. Computationally Guided Enzymatic Studies on Schizochytrium -Sourced Malonyl-CoA:ACP Transacylase. Journal of Agricultural and Food Chemistry, 2022, 70, 43, 13922–13934

    9. M. Cao, V. Tran, J. Qin, A. Olson, S. Mishra, J. Schultz, C. Huang, D. Xie, H. Zhao*. Metabolic engineering of oleaginous yeast Rhodotorula toruloides for overproduction of triacetic acid lactone. Biotechnology and Bioengineering, 2022, 119:2529-2540

    10. Y. Xu, L. Yang, H. Wang, X. Wei, Y. Shi, D. Liang, M. Cao*, N. He*. Putative functions of EpsK in teichuronic acid synthesis and phosphate starvation in Bacillus licheniformis. Synthetic and Systems Biotechnology, 2022, 7(2): 815-823

    11. G. Chi, Y. Xu, X. Cao, Z. Li, M. Cao*, Y. Chisti*, N. He*. Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp. Biotechnology Advances, 2022, 55: 107897

    12. C. Lopez, M. Cao*, Z. Yao, Z. Shao*. Revisiting the unique structure of autonomously replicating sequences in Yarrowia lipolytica and its role in pathway engineering. Applied Microbiology and Biotechnology, 2021, 105: 5959-5972

    13. T. Wang*, B. Si, Z. Gong, Y. Zhai, M. Cao*, C. Peng. Co-hydrothermal carbonization of food waste-woody biomass blend: interaction effects on the hydrochar properties and nutrients characteristics. Bioresource Technology, 2020, 316: 123900

    14. M. Cao#, V. Tran#, H. Zhao. Unlocking nature’s biosynthetic potential by directed genome evolution. Current Opinion in Biotechnology, 2020, 66: 95-104    

    15. Y. Zhao, Z. Yao, D. Ploessl, M. Monti, D. Schindler, M. Gao, Y. Cai, M. Qiao, C. Yang*, M. Cao*, Z. Shao*. Leveraging the Hermes transposon to accelerate the development of nonconventional yeast-based microbial cell factories. ACS Synthetic Biology, 2020, 9(7): 1736-1752

    16. M. Cao#, Z. Fatma#, X. Song, P. Hsieh, V. Tran, W. Lyon, M. Sayadi, Z. Shao, Y. Yoshikuni, H. Zhao. A genetic toolbox for metabolic engineering of Issatchenkia orientalisMetabolic Engineering2020, 59: 87-97

    17. M. Cao#M. Gao#, M. Suástegui, Y. Mei, Z. Shao. Building microbial factories for the production of aromatic amino acid pathway derivatives: from commodity chemicals to plant-sourced natural products. Metabolic Engineering. 2020, 58: 94-132

    18. J. Lian#, C. Schultz#, M. Cao#, M. HamediRad#, H. Zhao. Multi-functional genome-wide CRISPR system for high throughput genotype-phenotype mapping, Nature Communications. 2019, 10:5794

    19. V. Tran#M. Cao#, Z. Fatma, X. Song, H. Zhao. Development of a CRISPR/Cas9-based tool for gene deletion in Issatchenkia orientalismSphere. 2019, 4(3): e00345-19

    20. M. Cao, M. Gao, D. Ploessl, Z. Shao. CRISPR-mediated genome editing and gene repression in Scheffersomyces stipitisBiotechnology Journal.2018, 13, 1700598

    21. M. Cao#, J. Feng#, S. Sirisansaneeyakul, C. Song, Y. Chisti. Genetic and metabolic engineering for microbial production of poly-γ-glutamic acid. Biotechnology Advances, 2018, 36: 1424-1433

    22. M. CaoA. Seetharam, A. Severin, Z. Shao. Rapid isolation of centromeres from Scheffersomyces stipitisACS Synthetic Biology, 2017, 6(11), 2028-2034

    23. M. Cao, M. Gao, C. Lopez-Garcia, Y. Wu, A. Seetharam, A. Severin, Z. Shao. Centromeric DNA facilitates nonconventional yeast genetic engineering. ACS Synthetic Biology, 2017, 6(8): 1545-1553

    24. D. Ploessl, Y. Zhao, M. Cao, S. Ghosh, C Lopez-Garcia, M. Sayadi, S Chudalayandi, A. Severin, L. Huang, M. Gustafson, Z. Shao. A repackaged CRISPR platform unlocks the utility of non-homologous end joining in microbial factory engineering. Nature Chemical Biology. 2021, 1-9

    25. Y. Wang#, P. Xue#M. Cao, T. Yu, S. Lane, H. Zhao. Directed evolution: Methodologies and applications. Chemical Reviews. 2021, 121(20): 12384–12444 

    26. J. Feng, J. Zhang, Y. Ma, Y. Feng, S. Wang, N. Guo, H. Wang, P. Wang, P. Jiménez-Bonilla, Y. Gu, J. Zhou, Z. Zhang, M. Cao, D. Jiang, S. Wang, X. Liu, Z. Shao, I. Borovok, H. Huang, Y. Wang. Renewable fatty acid ester production in ClostridiumNature Communications. 2021, 12: 4368

授权专利:

    1. H. Zhao, M. Cao, V. Tran, Z. Fatma, Genetic toolbox for metabolic engineering of nonconventional yeast. US Patent, 2020, 17/180,741

    2. Z. Shao, M. Cao, M. Suastegui, M. Gao. Methods and compositions for production of aromatic and other compounds in yeast. US Patent, 2019, 16/019,822