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成果及论文

Independent research:

1. Wei Wang, Yuanyuan Peng, Yang Liu, Yanchun Lin, Fei Zhao, Qinlin Chen, Liangming Xuan, Qiongjiao Yan, Fen-Er Chen,* and Hui Zhou* Nucleophilic addition of bulk chemicals with imines using N-functionalized hydroxylamine reagents as precursorsNat. Commun. 2025, 16(1), 168. [Link]

2. Liqun Hu, Yao Xiang, Qing Huang, Hui Zhou*, and Youwei Xie* Late-stage C–H Deuteration of (Hetero)Arenes via Deuterium-Bonding Enhanced Rhenium Catalysis. ACS Catal. 2025, 15, 4711. [Link]

3. Yixuan Zheng, Xinhao Deng, Fei Zhao, Yuanyuan Peng, Qiongjiao Yan,* Wei Wang,* Fener Chen, and Hui Zhou* Pd-catalyzed asymmetric allylic alkylation of N-hydroxyphthalimide esters with allyl acetates. Org. Chem. Front. 2025, doi: https://pubs.rsc.org/en/content/articlelanding/2025/qo/d4qo02257b. [Link]

4. Li-Sheng Wang, Yu-Man Song, You Zhou, Yong-Xing Tang, Chun-Yan Wu, Zhi-Cheng Yu, Hui Zhou,* Kai-Lu Zheng,* and An-Xin Wu* Iodine as Polarity-Reversal Catalyst: Synthesis of a FusedHeterocycle with Contiguous Stereocenters. Org. Lett. 2024, 27(1), 9196. [Link]

5. Wei Wang, Liangming Xuan, Qinlin Chen, Rundong Fan, Fei Zhao, Jianghu Dong, Haifeng Wang, Qiongjiao Yan, Hui Zhou,* and Fen-Er Chen* Copper-Catalyzed Asymmetric Remote C(sp3)-H Alkylation of N-Fluorocarboxamides with Glycine Derivatives and Peptides. J. Am. Chem. Soc. 2024, 146(9), 6307–6316. [Link] Highlighted by Synfacts[Link]


Before CCNU:

1. Hui Zhou, Yu Zhou, Han Yong Bae, Markus Leutzsch, Yihang Li, Chandra Kanta De, Gui-Juan Cheng*, and Benjamin List* Organocatalytic Stereoselective Cyanosilylation of Small Ketones. Nature 2022, 605(7908), 84–89. Highlighted by Nature Synthesis, Synform, Synfacts, X-MOL, 小柯化学, MPI-KOFO news, Analytik. News.

2. Hui Zhou, Roberta Properzi, Markus Leutzsch, Paola Belanzoni, Giovanni Bistoni, Nobuya Tsuji, Jung Tae Han, Chendan Zhu, and Benjamin List* Organocatalytic DYKAT of Si-Stereogenic Silanes. J. Am. Chem. Soc. 2023, 145(9), 4994–5000. Highlighted by Chem-Station.

3. Hui Zhou, Jung Tae Han, Nils Nöthling, Monika M. Lindner, Judith Jenniches, Clemens Kühn, Nobuya Tsuji, Li Zhang, and Benjamin List* Organocatalytic Asymmetric Synthesis of  Si-Stereogenic Silyl Ethers. J. Am. Chem. Soc. 2022, 144(23), 10156–10161. Highlighted by Synfacts, X-MOL, Chem-Station, CBG.

4. Hui Zhou, Han Yong Bae, Markus Leutzsch, Jennifer L. Kennemur, Diane Bécart, and Benjamin List* The Silicon–Hydrogen Exchange Reaction: A Catalytic σ-Bond Metathesis Approach to the Enantioselective Synthesis of Enol Silanes. J. Am. Chem. Soc. 2020, 142(32), 13695–13700.

5. Hui Zhou, Zhao Wei, Jinlong Zhang, Huameng Yang, Chungu Xia, and Gaoxi Jiang* From Pd-Catalysis to Brønsted Acid-Catalysis: Highly Enantioselective Regiodivergent Addition of Alkoxyallenes to Pyrazolones. Angew. Chem. Int. Ed. 2017, 56(4), 1077–1081. (Selected as Back Cover)

6. Joyce A. A. Grimm, Hui Zhou, Roberta Properzi, Markus Leutzsch, Giovanni Bistoni, Johanna Nienhaus, Benjamin List* The “Impossible” Neral to (1R,6S)-Isopiperitenol Conversion Toward Cannabinoids and Menthol. Nature 2023, 615(7953), 634–639.

7. Hui Zhou, Hetti Handi Chaminda Lakmal, Jonathan M. Baine, Henry U. Valle, Xue Xu, and Xin Cui* Catalytic [2+2+2] Cycloaddition with Indium (III)-Activated Formaldimines: a Practical and Selective Access to Hexahydropyrimidines and 1, 3-Diamines from Alkenes. Chem. Sci. 2017, 8(9), 6520–6524. (Highlighted by X-MOL)

8. Xiaolin Qian†, Hui Zhou†, James Lucore, Xuesong Wang, Henry U Valle, Bruno Donnadieu, Xue Xu, and Xin Cui* Fe(III)-Based Tandem Catalysis for Amidomethylative Multiple Substitution Reactions of α-Substituted Styrene Derivatives. ACS Catal. 2020, 10(18), 10627–10636. (†: co-first author)

9. Hui Zhou, Jinlong Zhang, Huameng Yang, Chungu Xia, and Gaoxi Jiang* Rh-Catalyzed Double Methyl-Oxygen Bonds Cleavage: A Methyl Transfer Reaction from Di/Tris(o-methoxyphenyl) phosphine to Aryl Acids. Organometallics 2016, 35(19), 3406–3412.

10. Hui Zhou, Jixing Li, Huameng Yang, Chungu Xia*, and Gaoxi Jiang* Triarylphosphines as Aryl Donors for Pd(II)-Catalyzed Aromatic Coupling of Oxabenzonorbornadienes. Org. Lett. 2015, 17(18), 4628–4631. Highlighted by X-MOL.

11. Hui Zhou, Huameng Yang, Muwen Liu, Chungu Xia*, and Gaoxi Jiang* Brønsted Acid Accelerated Pd-Catalyzed Direct Asymmetric Allylic Alkylation of Azlactones with Simple Allylic Alcohols: A Practical Access to Quaternary Allylic Amino Acid Derivatives. Org. Lett. 2014, 16(20), 5350–5353.

12. Hui Zhou, Huameng Yang, Hongyu Yin, Muwen Liu, Chungu Xia*, and Gaoxi Jiang* Palladium Catalyzed Direct Allylation of Azlactones with Simple Allylic Alcohols in the Absence of Any Activators. RSC Adv. 2014, 4(49), 25596–25599.

13. Hui Zhou, Pinglu Zhang, and Benjamin List* The Silicon–Hydrogen Exchange Reaction: Catalytic Kinetic Resolution of 2-Substituted Cyclic Ketones. Synlett 2021, 32(19), 1953–1956.

14. Benjamin List*, Hui Zhou, Gui-Juan Cheng, Yu Zhou, Han-Yong Bae, Markus Leutzsch, Yihang Li Organocatalytic Stereoselective Cyanosilylation of Small Ketones. SYNTHESIS-STUTTGART 2022, 54, A146–A149.

15. Chendan Zhu, Francesca Mandrelli, Hui Zhou, Rajat Maji, and Benjamin List* Catalytic Asymmetric Syntheiss of Unprotected β2-Amino Acids. J. Am. Chem. Soc. 2021, 143(9), 3312–3317.

16. Tynchtyk Amatov, Nobuya Tsuji, Rajat Maji, Lucas Schreyer, Hui Zhou, Markus Leutzsch, and Benjamin List* Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes. J. Am. Chem. Soc. 2021, 143(36), 14475–14481.

17. Jung Tae Han, Hui Zhou, and Benjamin List* Brønsted Acid Catalyzed Asymmetric Silylation of Biaryl Diols. Synlett 2023, doi: 10.1055/a-2100-1575.

18. Shen Li, Hui Zhou, and Benjamin List* Synthesis and Resolution of an Axially Chiral Spirocyclic Quaternary Ammonium Ion-Based Phase-Transfer Catalyst. Asian J. Org. Chem. 2023, 12, e202300241.

19. Chunming Gui, Yuanyuan Peng, Yang Zhou, Yixuan Zheng, Haifeng Wang, Qiongjiao Yan, Hui Zhou, Wei Wang*, Fen-Er Chen* Cu-Catalyzed Intermolecular Asymmetric Propargylic Substitution of N-Hydroxyphthalimide Esters with Propargyl Carbonates. ACS Catal. 2023, 13, 13735–13742.

20. Hetti Handi Chaminda Lakmal, Jacob Istre, Xiaolin Qian,  Hui Zhou,  Henry U. Valle, Xue Xu*, and Xin Cui* Catalytic Amidomethylative [2+2+2] Cycloaddition of Formaldimine and Styrenes toward N-heterocycles. Synthesis 2022, 54(09), 2165–2174.

21. Huameng Yang, Hui Zhou, Hongyu Yin, Chungu Xia, and Gaoxi Jiang* Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Brønsted Acid Catalysis. Synlett 2014, 25(15), 2149–2154.

22. Ruwei Cao, Jinlong Zhang, Hui Zhou, Huameng Yang, and Gaoxi Jiang* Palladium-Catalyzed Highly Atom-Economic Allylation of Oxindoles with Vinyl Cyclopropanes. Org. Biomol. Chem. 2016, 14(7), 2191–2194.

23. Jixing Li, Hui Zhou, Jinlong Zhang, Huameng yang, and Gaoxi Jiang* AgNO3 as Nitrogen Source for Rhodium (Ш)-Catalyzed Synthesis of 2-Aryl-2H-Benzotriazoles from Azobenzenes. Chem. Commun. 2016, 52(61), 9589–9592.

24. Muwen Liu, Jinlong Zhang, Hui Zhou, Huameng Yang, Chungu Xia*, and Gaoxi Jiang* Efficient Hydroarylation and Hydroalkenylation of Vinylarenes by Brønsted Acid Catalysis. RSC Adv. 2016, 6(80), 76780–76784.

25. Benjamin List, Joyce Grimm, Luping Liu, Hui Zhou, Alexander Zwerschke Process for the Asymmetric Synthesis of Isopiperitenol. EP 4023626A1, 2022.

26. Yang Liu, Tongyao Zhou, Liangming Xuan, Yanchun Lin, Fuqi Li, Haifeng Wang, Jian Lyu, Qiongjiao Yan, Hui Zhou, Wei Wang*, Fen-Er Chen* Visible-Light-Driven C,N-Selective Heteroarylation of N-Fluoroalkyl Hydroxylamine Reagents with Quinoxalin-2(1H)-ones. Org. Lett. 2023, 25(48), 8693–8699.

27. Jung Tae Han, Nobuya Tsuji, Hui Zhou, Markus Leutzsch, Benjamin List* Organocatalytic asymmetric synthesis of Si-stereogenic silacycles. Nat. Commun. 2024, 15(1), 5846.