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杨丹 长江学者 晨兴化学生物学讲席教授    


丹教1985年本科毕业于复旦大学化学系,1988年获得哥伦比亚大学硕士学位,1991年获颁普林斯顿大学博士学位,之后在哈佛大学完成两年博士后研究,19932021年历任香港大学化学系助理教授、副教授、教授、讲座教授、晨兴化学生物学讲席教授。20218月全职加入西湖大学,任西湖大学化学生物学讲席教授。

杨丹课题组重点发展化学生物学,注重化学、生物、医学交叉转化研究,聚焦多模态探针开发与跨尺度生物成像,为人类疾病提供新的诊疗策略。研究涵盖以下三个方向:

1)专注于研发小分子探针,用于生物体系内活性氧、蛋白、核酸、脂质体的检测和细胞、组织及活体成像,并发展单分子成像技术,以新型探针为核心、探究微观基础生物机制;

2)设计人工离子传输体,开发靶向肿瘤干细胞的活性药物分子;

3)探究生物系统中信号转导过程以及药物靶向蛋白。

杨丹教授曾获得Mr. and Mrs. Sun Chan有机化学纪念奖、百时美施贵宝基金会颁发的有机合成化学奖、裘槎高级研究员奖、香港十大杰出青年、礼来亚洲杰出科学奖、晨兴化学生物学讲席教授、诺华化学奖席、世界科学院化学奖、中国青年女科学家奖、卓越学科领域计划首席科学家和国际有机化学基金会吉田奖等。现任Curr. Opin. Chem. Biol.总主编,曾任Org. Lett.副主编、ACS Chem. Biol.客座主编、Acc. Chem. Res.编委等。


Professional Activities:

Editor-in-chief of Current Opinion in Chemical Biology (2020-)

Associate Editor of Organic Letters (2010-2013)

Guest Editor for ACS Chemical Biology on Sensors (2018)

Member of Editorial Board of Organic Chemistry Frontiers (2018-present)

Member of Editorial Board of Current Opinion in Chemical Biology (2017-2019)

Member of Editorial Advisory Board of Accounts of Chemical Research (2007-2016)

Member of Editorial Advisory Board of ACS Chemical Biology (2012-)

Member of Editorial Advisory Board of Organic Letters (2008-2009; 2014-)

Member of Editorial Advisory Board of The Journal of Organic Chemistry (2010-2017)

Member of International Advisory Board of Chemistry – An Asian Journal (2009-2017)

Member of Editorial Advisory Board for Beilstein Journal of Organic Chemistry (2005-)

Member of Faculty of 1000 (Biology Reports Ltd.), in the Macromolecular Chemistry Section under Chemical Biology Faculty (2004-).

Guest Editor for Tetrahedron Symposium-in-Print on Recent Advances in Oxidation Chemistry (2006)

Member of the American Chemical Society (1988-)

Visiting Professor, Lanzhou University (01/2000-12/2004)

Visiting Professor, Shanghai Institute of Materia Medica (07/2001-)

Professor of Chemistry, Fudan University (06/2001-05/2004)

Special Chair Professor, Fudan University (05/2004-)

Chang-Jiang Chair Professor, Fudan University (03/2006-02/2009)


Lectureship Awards:

Science Lecture at South University of Science and Technology (Mar. 2019; Shenzhen, China)

Distinguished Scientist Visiting Fellowship at Ben-Gurion University of the Negev (May 2018; Beer-Sheva, Israel)

Qiushi Lecture at Zhejiang University (May 2015; Hangzhou, China)

Asian Core Program Lectureship Award (2014; Japan and China)

Nankai University Lectureship in Organic Chemistry (Jun. 2013; Tianjin, China)

Eli Lilly lecturer in Organic Chemistry, Massachusetts Institute of Technology (Mar. 2009; Cambridge, USA)

Novartis Chemistry Lecturer, Novartis Institute for Biomedical Research (Sept. 2008; Basel, Switzerland)

Abbott Process Chemistry Lecturer, University of Wisconsin (May 2006; Madison, USA)

LEO Pharma Lecturer, Technical University of Denmark (May 2006; Copenhagen, Denmark)

Rosalind Franklin International Lecturer, Imperial College (Mar. 2004; London, U.K.)

Aulin-Erdtman Lecturer, Royal Institute of Technology (Dec. 2002; Stockholm, Sweden)