Seminars in Immunology is a review journal dedicated to keeping scientists informed of developments in the field of immunology on a topic by topic basis. Each issue is thematic in approach, devoted to an important topic of interest to immunologists, focusing on recent advances across a broad spectrum of research, from the molecular and cellular basis of the immune response to the possibilities for its manipulation. Every issue is edited by a guest editor, an internationally acknowledged expert in the field, and contains six to eight authoritative invited reviews on different aspects of the subject area. The aim of each issue is to provide a coordinated, readable, and lively review of a selected area, published rapidly to ensure currency.

Topics Covered in Earlier Issues Include:

• Mechanism of V(D)J rearrangement
• Commitment to CD4 and CD8 lineages
• Mechanisms of T cell help
• Lessons from the LPR mouse
• Phosphatidylinositol-linked molecules in T-cell activation

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Editor
A. Mantovani
University of Milan, Milano, Italy
Editorial Advisory Board
A.K. Abbas
University of California San Francisco, San Francisco, California, United States
D. Cua
Merck and Co Inc West Point, West Point, Pennsylvania, United States
C.A. Dinarello
University of Colorado, Denver, Colorado, United States
D. Littman
NEW YORK UNIVERSITY SCHOOL OF MEDICINE, New York, New York, United States
L. O'Neill
University of Dublin Trinity College School of Biochemistry and Immunology, Dublin 2, Ireland
R. Rappuoli
GSK Vaccines SRL, Siena, Italy
F. Sallusto
Institute for Research in Biomedicine, Bellinzona, Switzerland
P.J. Sansonetti
Institute Pasteur, Paris, France
T. Taniguchi
The University of Tokyo, Bunkyo-Ku, Tokyo, Japan
G. Trinchieri
National Cancer Institute Experimental Immunology Branch, Frederick, Maryland, United States