Journal of Applied Toxicology publishes peer-reviewed original reviews and hypothesis-driven research articles on mechanistic, fundamental and applied research relating to the toxicity of drugs and chemicals at the molecular, cellular, tissue, target organ and whole body level in vivo (by all relevant routes of exposure) and in vitro / ex vivo. All aspects of toxicology are covered (including but not limited to nanotoxicology, genomics and proteomics, teratogenesis, carcinogenesis, mutagenesis, reproductive and endocrine toxicology, toxicopathology, target organ toxicity, systems toxicity (eg immunotoxicity), neurobehavioral toxicology, mechanistic studies, biochemical and molecular toxicology, novel biomarkers, pharmacokinetics/PBPK, risk assessment and environmental health studies) and emphasis is given to papers of clear application to human health, and/or advance mechanistic understanding and/or provide significant contributions and impact to their field.
In addition Journal of Applied Toxicology also publishes analytical toxicology, ecotoxicology (vertebrate laboratory or field studies), new techniques and method development studies, (including research on animal alternatives and in silicomodelling) and applied regulatory toxicology on novel or existing drugs and chemicals, addressing novel, important or topical aspects of toxicology.
Reviews, mini-reviews and hypothesis/theoretical papers on any aspect of toxicology including individual chemicals and multidisciplinary subjects are welcomed (see specific instructions below).
High quality histopathology photomicrographs, specimen photographs and complex diagrams (including gene regulation) will be printed in color free to authors.
Authors wishing to submit a manuscript on chemical weapons material's must contact the Editor-in-Chief first (seeInstructions For Authors) to discuss merit and scope.

EDITOR-IN-CHIEF
(Europe, Middle East and Africa)

Dr. Philip W. Harvey
e-mail: drphilip.harvey@gmail.com










U.S. AND CANADA EDITOR
(North America, South America and Canada)

Dr. Saura Sahu
Division of Toxicology
Office of Applied Research and Safety Assessment
Center for Food Safety and Applied Nutrition
U.S. Food and Drug Administration
8301 Muirkirk Road, Laurel
MD 20708, USA
e-mail: saura.sahu@fda.hhs.gov

U.S. AND CANADA EDITOR
(North America, South America and Canada)

Dr. Warren Foster
Department of Obstetrics & Gynecology
McMaster University
Canada
e-mail: fosterw@mcmaster.ca

ASIAN EDITOR
(Japan, Asia and Australasia)

Dr. Taisen Iguchi
Professor, Department of Bio-Environmental Science
National Institute for Basic Biology
5-1 Higashiyama
Myodaiji
Okazaki Aichi 444-8787
Japan
e-mail: taisen@nibb.ac.jp

REVIEWS EDITOR
(USA; Americas and Canada)

Dr. Dan Casciano
Department of Applied Science
Nanotechnology Center
University of Arkansas at Little Rock
Little Rock, AR 72204
USA
e-mail: dcasciano@sbcglobal.net

REVIEWS EDITOR
(Sweden: Europe)

Dr. Steffen Ernst
Head Translational Patient Safety
AstraZeneka R&D, Mölndal, Sweden
e-mail: Steffen.Ernst@astrazeneca.com

EDITORS EMERITI

Michael Greenwood

Harry Salem

EDITORIAL ADVISORY BOARD

L. C. Abbott, USA

K. Arizono, Japan

A. Baccarelli, USA

R. E. Baynes, USA

P. Baldrick, UK

D. Basketter, UK

A. Bauer, USA

G. Bernardini, Italy

C. Betts, UK

A. Biris, USA

D. Bowen, UK

R. C. Burghardt, USA

S. Chivers, Switzerland

T. Chen, China

D. Cyr, Canada

P. Darbre UK

J. Descotes, France

M. Ehrich, USA

D. J. Everett, UK

N. Filipov, USA

S. Garrett, USA

P. Goldfarb, UK

T. Hartung, USA

G. Healing, UK

T. Hutchinson, UK

K. Igarashi, Japan

W. Kempinas, Brazil

H. Kojima, Japan

R. Lantz, USA

L. H. Lash, USA

H. Maibach, USA

M. Maccani, USA

K. L. McCoy, USA

A. Merrick, USA

S. A. Meyer, USA

S. Milanez, USA

G. Miller, USA

N. A. Monteiro-Riviere, USA

T. Nagao, Japan

J. Pauluhn, Germany

L. Perharic, Slovenia

G. A. Petroianu, USA

A. Ramesh, USA

S. Rocks, UK

S. S. Sánchez, Argentina

P. M. Schlosser, USA

M. Sepulveda, USA

A. G. Smith, UK

S. Somji, USA

H. Soreq, Israel

C. Sutcliffe, UK

K. Tanemura, Japan

N. Tatarazako, Japan

J. Trempy, USA

M. Uzumcu, USA

L. G. Valerio, Jr., USA

L. Verschaeve, Belgium

H. Wanibuchi, Japan

D. B. Warheit, USA

H. Watanabe, Japan

K. Welch, USA

M. Whalen, USA

T. White, USA

L. Winn, Canada

S.–Q. Xu, China

J. Yager, USA

H. Yamamoto, Japan

T. Yamazaki, Japan

C.–J. Ying, China