Current Opinion in Structural Biology (COSB) aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.

In COSB, we help the reader by providing in a systematic manner:

1. The views of experts on current advances in their field in a clear and readable form.
2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.

The journal is part of the Current Opinion and Research (CO+RE) suite of journals and is a companion to the primary research, open access journal, Current Research in Structural Biology. CO+RE journals leverage the Current Opinion legacy of editorial excellence, high-impact, and global reach to ensure they are a widely-read resource that is integral to scientists' workflows.

COSB will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.

Division of the subject into sections

The subject of Structural Biology is divided into twelve themed sections, each of which is reviewed once a year. Each issue contains two sections, and the amount of space devoted to each section is related to its importance.

Folding and Binding
Nucleic acids and their protein complexes
Macromolecular Machines
Theory and Simulation
Sequences and Topology
New constructs and expression of proteins
Membranes
Engineering and Design
Carbohydrate-protein interactions and glycosylation
Biophysical and molecular biological methods
Multi-protein assemblies in signalling
Catalysis and Regulation


Selection of topics to be reviewed

Section Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Section Editors commission reviews from authorities on each topic that they have selected. The Editorial Board provides support to the Editors and the Section Editors with their comments and suggestions on names and topics.

Review articles in COSB are by invitation only. The journal does not accept manuscripts other from those invited by section editors, appointed by Editors-in-Chief.

Review Articles

Authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous two years.

Editorial Overview

Section Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments. This successful format has made COSB one of the most highly regarded review journals in the field.

Editor-in-Chief
Tom Blundell
University of Cambridge, Cambridge, United Kingdom Structural and computational biology and its applications to drug discovery.
Ruth Nussinov
NCI at Frederick, Frederick, Maryland, United States Protein structure, dynamics and function, signaling, allosteric drugs, cellular networks, key oncogenic proteins, computational biology
Editorial Board
Edward Baker
Auckland, New Zealand
Nenad Ban
Zurich, Switzerland Ribosomes, protein synthesis, protein targeting,  translation regulation,  macromolecular assemblies,  multi enzymes,  structural biology,  biochemistry
Maurizio Brunori
Rome, Italy
Jane Clarke
Cambridge, United Kingdom
Elena Conti
Munich, Germany
Valerie Daggett
Seattle, WA, United States
William DeGrado
San Francisco, CA, United States
David Eisenberg, MD
Los Angeles, CA, United States Novel multi-disciplinary strategies, integrative care
Ten Feizi
Harrow, United Kingdom
Juan Fernandez-Recio
Barcelona, Spain
Dave Fernig
Liverpool, United Kingdom
Fernando Gonzalez-Nilo
Santiago, Chile
Samar Hasnain
Liverpool, United Kingdom
Chuan He
Chicago, IL, United States Nucleic acid modification chemistry and biology
Richard Henderson
Cambridge, United Kingdom
Wim Hol
Seattle, WA, United States
Barry Honig
New York, NY, United States
Michael Levitt
Stanford, CA, United States
Barbara Mulloy
London, England, United Kingdom
Haruki Nakamura
Suita, Japan
Richard Neutze
Goteborg, Sweden
Martin Noble
Newcastle Upon Tyne, United Kingdom
Christine Orengo
London, United Kingdom
Lynne Regan
New Haven, CT, United States
Felix Rey, PhD
Paris, France
Carol Robinson
Oxford, United Kingdom
Rajan Sankaranarayanan, PhD
Hyderabad, India
Michal Sharon
Rehovot, Israel
Yigong Shi
Beijing, China
Yunyu Shi
Hefei, China
Raymond Stevens
La Jolla, CA, United States
Natalie Strynadka
Vancouver, BC, Canada X-ray crystallography, single particle cryoEM, structure based drug design, infectious disease, membrane protein complexes, bacterial cell wall biogenesis, bacterial secretion systems, glycoenzymes
John Tainer
La Jolla, CA, United States
Christopher Tate
London, United Kingdom
Dan Tawfik
Rehovot, Israel
Chandra Verma
Singapore
Soichi Wakatsuki
Stanford, CA, United States
Cynthia Wolberger
Baltimore, MD, United States
Peter Wright
La Jolla, CA, United States
Kurt Wüthrich
La Jolla, CA, United States
Todd Yeates
Los Angeles, CA, United States
Mingjie Zhang
Clear Water Bay, Kowloon, Hong Kong