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Current Opinion in Structural Biology (COSB) aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.
In COSB, we help the reader by providing in a systematic manner:
1. The views of experts on current advances in their field in a clear and readable form.
2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.
COSB will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.
Division of the subject into sections
The subject of Structural Biology is divided into twelve themed sections, each of which is reviewed once a year. Each issue contains two sections, and the amount of space devoted to each section is related to its importance.
- Folding and Binding
- Nucleic acids and their protein complexes
- Macromolecular Machines
- Theory and Simulation
- Sequences and Topology
- New constructs and expression of proteins
- Membranes
- Engineering and Design
- Carbohydrate-protein interactions and glycosylation
- Biophysical and molecular biological methods
- Multi-protein assemblies in signalling
- Catalysis and Regulation
Selection of topics to be reviewed
Section Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Section Editors commission reviews from authorities on each topic that they have selected. The Editorial Board provides support to the Editors and the Section Editors with their comments and suggestions on names and topics.
Review articles in COSB are by invitation only. The journal does not accept manuscripts other from those invited by section editors, appointed by Editors-in-Chief.
Review Articles
Authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous two years.
Editorial Overview
Section Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments. This successful format has made COSB one of the most highly regarded review journals in the field.
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Editor-in-Chief  University of Cambridge, Cambridge, United Kingdom Structural and computational biology and its applications to drug discovery. NCI at Frederick, Frederick, Maryland, United States Protein structure, dynamics and function, signaling, allosteric drugs, cellular networks, key oncogenic proteins, computational biologyEditorial Board Edward BakerAuckland, New Zealand Zurich, Switzerland Ribosomes, protein synthesis, protein targeting, translation regulation, macromolecular assemblies, multi enzymes, structural biology, biochemistryMaurizio BrunoriRome, ItalyCambridge, United Kingdom Elena ContiMunich, GermanyValerie DaggettSeattle, WA, United StatesWilliam DeGradoSan Francisco, CA, United StatesDavid Eisenberg, MDLos Angeles, CA, United States Novel multi-disciplinary strategies, integrative careTen FeiziHarrow, United KingdomJuan Fernandez-RecioBarcelona, SpainDave FernigLiverpool, United KingdomFernando Gonzalez-NiloSantiago, ChileSamar HasnainLiverpool, United KingdomChuan HeChicago, IL, United States Nucleic acid modification chemistry and biologyRichard HendersonCambridge, United KingdomWim HolSeattle, WA, United States New York, NY, United StatesMichael LevittStanford, CA, United StatesBarbara MulloyLondon, England, United KingdomHaruki NakamuraSuita, JapanRichard NeutzeGoteborg, SwedenMartin NobleNewcastle Upon Tyne, United KingdomChristine OrengoLondon, United KingdomLynne ReganNew Haven, CT, United States Paris, FranceCarol RobinsonOxford, United Kingdom Hyderabad, IndiaMichal SharonRehovot, Israel Beijing, ChinaRaymond StevensLa Jolla, CA, United StatesVancouver, BC, Canada X-ray crystallography, single particle cryoEM, structure based drug design, infectious disease, membrane protein complexes, bacterial cell wall biogenesis, bacterial secretion systems, glycoenzymes John TainerLa Jolla, CA, United StatesChristopher TateLondon, United KingdomSoichi WakatsukiStanford, CA, United StatesCynthia WolbergerBaltimore, MD, United StatesLa Jolla, CA, United States Kurt WüthrichLa Jolla, CA, United StatesLos Angeles, CA, United States Clear Water Bay, Kowloon, Hong Kong
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