The American Journal of Physiology-Gastrointestinal and Liver Physiology publishes papers focused on the physiology and pathophysiology of the digestive organs. Authors are encouraged to submit manuscripts dealing with growth and development, digestion, secretion, absorption, metabolism, and motility of these organs, as well as work dealing with immune and inflammatory processes and with neural, endocrine, and circulatory control mechanisms that affect digestive physiology or disease. Mechanistic studies using molecular, cell biological, immunological, biochemical, -omic, and morphological approaches that contribute to knowledge of normal physiology or pathophysiology are especially welcomed. Research ranging from molecular and cellular events to whole animal studies and translational studies in human samples is appropriate.