As explained in the Editorial Charter, ACM TIST welcomes innovative, high-impact articles on emerging or deployed intelligent systems and technology with solid evaluation or evidence of success on a variety of topics. These topics include, but are not limited to:

intelligent agent systems
intelligent bioinformatics and biomedical systems
intelligent information and multimedia systems
intelligent robotic systems
intelligent tutoring and educational systems
knowledge engineering, modeling and capture systems
knowledge based software engineering
large-scale machine learning systems and technology
machine learning applications
online commerce, games, information search and advertising systems
planning and scheduling systems
social intelligence systems
speech and language understanding and processing systems
user behavior modeling and learning, intelligent user interfaces
The journal also welcomes articles on multidisciplinary systems such as brain sciences, social intelligence, and integration of intelligent systems with business, science and engineering applications.