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个人简介

1995年09月至1999年07月大连理工大学应用化学专业,学士学位 1999年09月至2005年10月大连理工大学应用化学专业,博士学位 2006年01月至2006年11月美国Wayne State University化学系, 有机化学博士后 2006年12月至2009年11月美国University of Pittsburgh化学系, 有机化学博士后 2012年07月至2012年11月美国Washington University in St Louis医学院, 访问学者 2009年12月至2012年12月大连理工大学精细化工国家重点实验室副教授。 2012年12月至今 大连理工大学精细化工国家重点实验室教授 2014年06月至今 大连理工大学精细化工国家重点实验室博士生导师

研究领域

有机荧光染料的光物理现象,以及有机荧光染料的生物影像和生物靶标检测的应用 纳米荧光粒子的制备,以及其在纳米医学领域的应用

近期论文

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An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotination of Photosensitizers. Nature Communications, 2022, 13, 2225. Feng, Erting; Jiao, Long; Tang, Shanliang; Chen, Miaomiao; Lv, Shibo; Dapeng, Liu; Song, Jitao; Peng, Xiaojun; Song, Fengling;* Anti-Photobleaching Cyanine-Based Nanoparticles with Simultaneous PET and ACQ Effects for Improved Tumor Photothermal Therapy. Chemical Engineering Journal, 2022, 432, 134355. Feng, Erting; Liu, Yuhan; Lv, Shibo; Dapeng, Liu;* Huang, Shuheng; Li, Zhiliang; Song, Fengling.* Fine-Tuning Cu (II)-Induced Self-Assembly of Hydrophilic Cyanine Dyes for Enhanced Tumor Photothermal Therapy. Adv. Funct. Mater., 2022, 32, 2209258 Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759. Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 9590−9597. Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J. Am. Chem. Soc. 2008, 130, 16460–16461. Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. J. Am. Chem. Soc. 2007, 129, 12354–12355. Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171. Wu, Yingnan; Zhao, Yanliang; Hou, Haoran; Hong, Gaobo; Guo, Hanhui; Zhang, Ruiling; Chen, Wenlong; Tian, Jiarui; Lv, Shibo; Wang, Honglei; Wang, Meishan;* Wu, Chenyu;* Song, Fengling.* Oxygen-Insensitive Delayed Fluorescence Based on Singlet Manifold. Advanced Optical Materials, 2022, doi.org/10.1002/adom.202202413 Sun, Han; Guo, Ruihua; Guo, Yanhui; Song, Jitao; Li, Zhiliang;* Song, Fengling.* Boosting Type‑I and Type-II ROS Production of Water-Soluble Porphyrin for Efficient Hypoxic Tumor Therapy. Mol. Pharmaceutics, 2022, 19, doi.org/10.1021/acs.molpharmaceut.2c00822 Lv, Fangyuan; Fan, Xiaoxue; Liu, Dapeng;* Song, Fengling;* Photothermal agents based on small organic fluorophores with intramolecular motion. Acta Biomaterialia 2022, 149, 16-29. Feng, Erting; Liu, Yuhan; Lv, Shibo; Dapeng, Liu;* Huang, Shuheng; Li, Zhiliang; Song, Fengling.* Fine-Tuning Cu (II)-Induced Self-Assembly of Hydrophilic Cyanine Dyes for Enhanced Tumor Photothermal Therapy. Adv. Funct. Mater., 2022,32, 2209258. Lv, Shibo; Liu, Yuhan; Zhao, Yanliang; Fan, Xiaoxue; Lv, Fangyuan; Feng, Erting; Dapeng, Liu;* Song, Fengling.* Rational design of a small organic photosensitizer for NIR-I imaging-guided synergistic photodynamic and photothermal therapy. Biomater. Sci., 2022, 10, 4785-4795. Jin, Lin; Miao, Yuyang; Dapeng, Liu;* Song, Fengling.*Fe/Mn-Porphyrin Coordination Polymer Nanoparticles for Magnetic Resonance Imaging (MRI) Guided-Combination Therapy between Photodynamic Therapy and Chemodynamic Therapy. ChemistrySelect, 2022, 7, e202104366. Guo, Yanhui; Huang, Shuheng; Sun, Han; Wang, Zhe; Shao, Yutong; Li, Lukun; Li, Zhiliang;* Song, Fengling.* Tuning the aqueous self-assembly of porphyrins by varying the number of cationic side chains. J. Mater. Chem. B, 2022, 105, 5968–5975. Sun, Jinghan; Feng, Erting; Shao, Yutong; Lv, Fangyuan; Wu, Yingnan; Tian, Jiarui; Sun, Han; Song, Fengling.* A selenium-substituted heptamethine cyanine photosensitizer for near-infrared photodynamic therapy. ChemBioChem, 2022, e202200421. Wang, Donghui; Hou, Haoran; Chen, Wenlong; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on fluorescent probe for palladium(II) detection with a large Stokes shift and lysosomes-targeting ability. Tetrahedron Letters, 2022, 102,153932. Chen, Miaomiao; Zhao, Shuju; Zhu, Jialong; Feng, Erting; Lv, Fangyuan; Chen, Wenlong; Lv, Shibo; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* Open-Source and Reduced-Expenditure Nanosystem with ROS Self-Amplification and Glutathione Depletion for Simultaneous Augmented Chemodynamic/Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 20682-20692. An, Jing; Tang, Shanliang; Feng, Erting; Tian, Mingyu; Chen, Wenlong; Chen, Miaomiao; Hong, Gaobo; Peng, Xiaojun; Song, Fengling.* Naphthofluorescein-Based Organic Nanoparticles with Superior Stability for Near-Infrared Photothermal Therapy. Nanoscale, 2022, 14, 10051–10059. An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotination of Photosensitizers. Nature Communications, 2022, 13, 2225. Tian, Mingyu; Chen, Wenlong; Wu, Yingnan; An, Jing; Hong, Gaobo; Chen, Miaomiao; Song, Fengling;* Zheng, Wen-heng;* Peng, Xiaojun. Liposome-Based Nanoencapsulation of a Mitochondria-Stapling Photosensitizer for Efficient Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 12050-12058. Zhao, Yanliang; Wu,Yingnan; Chen, Wenlong; Zhang, Ruiling; Hong, Gaobo; Tian, Jiarui; Wang, Honglei; Zheng, Daoyuan; Zhou, Wu, Chenyu; Jiang, Xiao; Huo, Xinming; Sun, Lei;*; Deng, Weiqiao; Han, Keli; Song, Fengling.* The Second Excited Triplet−State Facilitates TADF and Triplet−Triplet Annihilation Photon Upconversion via a Thermally Activated Reverse Internal Conversion. Advanced Optical Materials, 2022,10, 2102275. Feng, Erting; Jiao, Long; Tang, Shanliang; Chen, Miaomiao; Lv, Shibo; Dapeng, Liu; Song, Jitao; Peng, Xiaojun; Song, Fengling.* Anti-Photobleaching Cyanine-Based Nanoparticles with Simultaneous PET and ACQ Effects for Improved Tumor Photothermal Therapy. Chemical Engineering Journal, 2022, 432, 134355. Chen, Shuang; Liu, Yongzhuo; Liang, Ri; Hong, Gaobo; An, Jing; Peng, Xiaojun; Zheng, Wen-heng;* Song, Fengling.* Self-assembly of amphiphilic peptides to construct activatable nanophotosensitizers for theranostic photodynamic therapy. Chinese Chemical Letters, 2021, 32, 3903-3906. Tang, Shanliang; An, Jing; Song, Fengling;* Lv, Meiheng; Han, Keli; Peng, Xiaojun. Extending the legible time of light-responsive rewritable paper with a tunable photochromic diarylethene molecule. ACS Applied Materials & Interfaces 2021, 13, 51441-51425. Chen, Miaomiao; Song, Jitao;* Zhu, Jialong; Hong, Gaobo; An, Jing; Feng, Erting; Peng, Xiaojun; Song, Fengling.* A Dual-Nanozyme-Catalyzed Cascade Reactor for Enhanced Photodynamic Oncotherapy against Tumor Hypoxia. Adv. Healthcare Mater., 2021, 10, 2101049. Shao, Yutong; Song, Jitao;* Li, Xiaorong; Ren, Guoqing; Song, Fengling;* Synthesis of Noble Metal M@YSiO 2 Yolk−Shell Nanoparticles with Thin Organic/Inorganic Hybrid Outer Shells via an Aqueous Medium Phase. Langmuir 2021, 37, 7237-7245. Liu, Yuhan; Chen, Miaomiao; Zhao,Yanliang; Lv, Shibo; Zheng, Daoyuan; Dapeng, Liu;* Song, Fengling;* A Novel D-A-D Photosensitizer for Efficient NIR Imaging and Photodynamic Therapy. ChemBioChem 2021, 22, 2161-2167. Lv, Fangyuan; Liu, Dapeng;* Zheng, Wen-heng; Zhao,Yanliang; Song, Fengling;* BOPHY-Based Aggregation-Induced-Emission Nanoparticle Photosensitizers for Photodynamic Therapy. ACS Appl. Nano Mater. 2021, 4, 6012-6019. Li, Xiaorong; Shao, Yutong; Lv, Shibo; Tian, Jiarui; Zheng, Daoyuan; Song, Jitao;* Song, Fengling;* Au@mSiO 2 core–shell nanoparticles loaded with fluorescent dyes: synthesis and application for imaging performance. Dalton Trans., 2021, 50, 5624-5631. Miao, Yuyang; Lv, Shibo; Zheng, Daoyuan; Liu, Yuhan; Liu, Dapeng;* Song, Fengling;* Porphyrin-based metal coordination polymers with self-assembly pathway-dependent properties for photodynamic and photothermal therapy. Biomater. Sci., 2021, 9, 2533-2541. Chen, Miaomiao; Liu, Dapeng; Liu, Fusheng; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* Recent advances of redox-responsive nanoplatforms for tumor theranostics. Journal of Controlled Release, 2021, 332,269-284. Jin, Lin; Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling;* Recent Development of Porous Porphyrin-based Nanomaterials for Photocatalysis. ChemCatChem, 2021, 13, 140—152. Lv, Shibo; Miao, Yuyang; Zheng, Daoyang; Li, Xiaoju; Liu,Dapeng*; Song, Fengling;* Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy. Mol. Pharmaceutics, 2021, 18, 1229−1237 Liu, Yuhan; Lv, Shibo; Liu,Dapeng; Song, Fengling;* Recent development of amorphous metal coordination polymers for cancer therapy. Acta Biomaterialia, 2020, 116, 16-31. Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling.* Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes. ChemBioChem, 2020, 21, 2098—2110. Ying, Huiyi; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on TADF chemosensor for sulfite with a microsecond-scale luminescence lifetime. Chemical Communications, 2020, 56, 10549—10551. Wu,Yingnan; Zhao, Yanliang; Zhou, Panwang; Zheng, Daoyuan; Wang, Honglei; Tang, Shanliang; Tian, Jiarui; Yang, Songqiu; Deng, Weiqiao; Han, Keli; Song, Fengling.* Enhancing Intersystem Crossing to Achieve Thermally Activated Delayed Fluorescence in a Water-Soluble Fluorescein Derivative with a Flexible Propenyl Group. J. Phys. Chem. Lett. 2020, 11, 5692–5698. Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759. Zheng, Jing; Liu, Yongzhuo; Song, Fengling;* Jiao, Long; Wu,Yingnan; Peng, Xiaojun. A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia. Chemical Communications, 2020, 56, 5819-5822. Wu,Yingnan; Jiao, Long; Song, Fengling;* Chen, Miaomiao; Liu, Dapeng;* Yang, Wei; Yuming, Sun; Hong, Gaobo; Wu,Yingnan; Liu, lingge; Peng, Xiaojun. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nano-encapsulation. Chemical Communications, 2019, 55, 14522--14525 Chen, Wenlong; Song, Fengling.* Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs. Chinese Chemical Letters, 2019, 30, 1717-1730. Liu, Zhiwei; Shi, Wenbo; Hong, Gaobo; Chen,Wenlong; Song, Bo; Peng, Xiaojun; Xiong, Xiaoqing;* Song, Fengling.* A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative. Journal of Controlled Release 2019, 310, 1−10. Jiao, Long; Zhang, Xiaoye; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Three-in-one Functional Silica Nanocarrier with Singlet Oxygen Generation, Storage/release and Self-monitoring for Enhanced Fractional Photodynamic Therapy. ACS Applied Materials & Interfaces 2019, 11, 27250-27257. Liu, Zhiwei; Song, Fengling;* Shi, Wenbo; Gurzadyan, Gagik; Yin, Huiyi; Song, Bo; Liang, Ri; Peng, Xiaojun. Nitroreductase-activatable theranostic molecules with high PDT efficiency under mild hypoxia based on a TADF fluorescein derivative. ACS Applied Materials & Interfaces 2019, 11, 15426−15435. Chen, Wenlong; Song, Fengling;* Tang, Shanliang; Hong, Gaobo; Wu,Yingnan; Peng, Xiaojun. Red-to-blue photon up-conversion with high efficiency based on a TADF fluorescein derivative. Chemical Communications, 2019, 55, 4375 - 4378 Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. Rational design of a visible-light photochromic diarylethene: a simple strategy by extending conjugation with electron donating groups. SCIENCE CHINA Chemistry 2019, 62, 451-459. Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201. Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262,958-965. An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy, 2018, 8(3), 032103.

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