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个人简介

教育经历 1999.3 - 2003.3 大连理工大学 无 博士 1992.9 - 1996.7 天津大学 精细化工 学士 1996.9 - 1999.3 天津大学 应用化学 硕士 1989.9 - 1992.7 四川省泸州市泸天化中学 无 工作经历 2009.12 - 至今 大连理工大学 教授 2005.7 - 2009.12 大连理工大学 副教授 2004.1 - 2005.7 大连理工大学 讲师

研究领域

新型高效有机荧光染料的研发 细胞生物学研究:荧光分子探针与融合蛋白标记技术的应用于诊断治疗 荧光探针及其应用:生物标记与荧光显微成像 包括 双光子荧光成像,激光共聚焦成像,荧光寿命成像,超分辨荧光成像 染料基自组装纳米材料应用于肿瘤联合治疗:光动力治疗、基因治疗与免疫治疗 染料基有机半导体材料及应用:有机薄膜太阳能电池

近期论文

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张新富.Cyclo-Ketal Xanthene Dyes: A New Class of Near-Infrared Fluorophores for Super-Resolution Imaging of[J],Chem. Eur. J.,2021 Wang, Zechen,Zhang, Mingyan,Xiao, Yi,Zhang, Qinghao,Liu, Junwen,Sui, Ran,Li, Yahui,Li, Yue,Zhang, Xinfu,Yu, Haibo,Jing, Kui.A twist six-membered rhodamine-based fluorescent probe for hypochlorite detection in water and lys[J],ANALYTICA CHIMICA ACTA,2019,1082:116-125 Ye, Zhiwei,Yang, Wei,Zheng, Ying,Chi, Weijie,Liu, Xiaogang,Huang, Zhenlong,Xiao, Yi,Wang, Chao,Li, Xiaoyuan.Quaternary Piperazine-Substituted Rhodamines with Enhanced Brightness for Super-Resolution Imaging[J],JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2019,141(37):14491-14495 华雪莲,张树彪,肖义,张明兴,华德海,海华.新型阳离子脂质体制备及应用研究[J],化学研究与应用,2019,31(2):177-183 Zhang, Xinfu,Sun, Qin,Huang, Zhenlong,Huang, Lirong,Xiao, Yi.Immobilizable fluorescent probes for monitoring the mitochondria microenvironment: a next step fro[J],JOURNAL OF MATERIALS CHEMISTRY B,2019,7(17):2749-2758 Huang, Zhenlong,Li, Ning,Zhang, Xinfu,Wang, Chao,Xiao, Yi.Fixable Molecular Thermometer for Real-Time Visualization and Quantification of Mitochondrial Temp[J],ANALYTICAL CHEMISTRY,2018,90(23):13953-13959 Zhang, Xinfu,Wang, Benlei,Xiao, Yi,Wang, Chao,He, Ling.Targetable, two-photon fluorescent probes for local nitric oxide capture in the plasma membranes o[J],ANALYST,2018,143(17):4180-4188 Yu, Changjiang,Huang, Zhenlong,Wang, Xinru,Miao, Wei,Wu, Qughua,Wong, Wai-Yeung,Xiao, Yi,Jiao, Lijuan,Hao, Erhong.A Family of Highly Fluorescent and Unsymmetric Bis(BF2) Chromophore Containing Both Pyrrole and N-[J],ORGANIC LETTERS,2018,20(15):4462-4466 Luo, Xiao,Qian, Xuhong,Yang, Youjun,Yang, Haotian,Wang, Haolu,Ye, Zhiwei,Zhou, Zhongneng,Gu, Luyan,Chen, Jinquan,Xiao, Yi,Liang, Xiaowen.Highly Sensitive Hill-Type Small-Molecule pH Probe That Recognizes the Reversed pH Gradient of Can[J],ANALYTICAL CHEMISTRY,2018,90(9):5803-5809 Bian, Hui,Song, Xinbo,Li, Ning,Man, Huizi,Xiao, Yi.Quantitatively monitoring oxygen variation in endoplasmic reticulum with a fluorophore-phosphor en[J],JOURNAL OF MATERIALS CHEMISTRY B,2018,6(11):1699-1705 He, Haihong,Ye, Zhiwei,Zheng, Ying,Xu, Xiu,Guo, Chunlei,Xiao, Yi,Yang, Wei,Qian, Xuhong,Yang, Youjun.Super-resolution imaging of lysosomes with a nitroso-caged rhodamine[J],CHEMICAL COMMUNICATIONS,2018,54(23):2842-2845 He, Haihong,Ye, Zhiwei,Xiao, Yi,Yang, Wei,Qian, Xuhong,Yang, Youjun.Super-Resolution Monitoring of Mitochondrial Dynamics upon Time-Gated Photo-Triggered Release of N[J],ANALYTICAL CHEMISTRY,2018,90(3):2164-2169 Yu, Jinfeng,Bian, Hui,Man, Huizi,Li, Ning,Xie, Lijuan,Xiao, Yi.Two-photon excitable red fluorophores for imaging living cells[J],DYES AND PIGMENTS,2018,149:851-857 Haihong He,Zhiwei Ye,肖义,杨薇,钱旭红,Youjun Yang.Super-Resolution Monitoring of Mitochondrial Dynamics upon TimeGated Photo-Triggered Release of Nitr[J],Anal. Chem.,2018,90:2164-2169 Wang, Helin,Chen, Lingcheng,Xiao, Yi.Perylene diimide arrays: promising candidates for non-fullerene organic solar cells[J],JOURNAL OF MATERIALS CHEMISTRY C,2017,5(48):12816-12824 黄振龙,陈令成,肖义.可固定性荧光探针:线粒体成像的可靠工具[J],应用化学,2017,34(12):1370-1378 Li, Guli,Zhang, Bei,Song, Xinbo,Xia, Ying,Yu, Haibo,Zhang, Xinfu,Xiao, Yi,Song, Youtao.Ratiometric imaging of mitochondrial pH in living cells with a colorimetric fluorescent probe base[J],SENSORS AND ACTUATORS B-CHEMICAL,2017,253:58-68 Wang, Helin,Chen, Lingcheng,Xiao, Yi.A simple molecular structure of ortho-derived perylene diimide diploid for non-fullerene organic s[J],JOURNAL OF MATERIALS CHEMISTRY A,2017,5(42):22288-22296 Song, Xinbo,Bian, Hui,Wang, Chao,Hu, Mingyu,Li, Ning,Xiao, Yi.Development and applications of a near-infrared dye-benzylguanine conjugate to specifically label [J],ORGANIC & BIOMOLECULAR CHEMISTRY,2017,15(38):8091-8101 Yang, Fu,Wang, Chao,Wang, Lu,Ye, Zhi-Wei,Song, Xin-Bo,Xiao, Yi.Hoechst-naphthalimide dyad with dual emissions as specific and ratiometric sensor for nucleus DNA [J],CHINESE CHEMICAL LETTERS,2017,28(10,SI):2019-2022 Wang, Helin,Chen, Lingcheng,Xiao, Yi.Heterologous perylene diimide arrays: potential non-fullerene acceptors in organic solar cells[J],JOURNAL OF MATERIALS CHEMISTRY C,2017,5(34):8875-8882 Wang, Chao,Song, Xinbo,Xiao, Yi.SNAP-Tag-Based Subcellular Protein Labeling and Fluorescent Imaging with Naphthalimides[J],CHEMBIOCHEM,2017,18(17):1762-1769 Wang, Helin,Chen, Lingcheng,Zhao, Zhenbo,Xiao, Yi.Aryl-bisalkynyl bridged perylene diimides dimers: Efficient synthesis, properties and improved ele[J],DYES AND PIGMENTS,2017,144:184-189 Jiang, Xin-Dong,Guan, Jian,Bian, Hui,Xiao, Yi.A cinnamoyl substituted Nile Red-based probe to detect hydrazine[J],TETRAHEDRON LETTERS,2017,58(24):2351-2354 Wang, Chao,Song, Xinbo,Chen, Lingcheng,Xiao, Yi.Specifically and wash-free labeling of SNAP-tag fused proteins with a hybrid sensor to monitor loc[J],BIOSENSORS & BIOELECTRONICS,2017,91:313-320 Song, Xinbo,Li, Ning,Wang, Chao,Xiao, Yi.Targetable and fixable rotor for quantifying mitochondrial viscosity of living cells by fluorescen[J],JOURNAL OF MATERIALS CHEMISTRY B,2017,5(2):360-368 叶智伟,杨薇,肖义.光激活定位超分辨荧光成像的罗丹明分子设计[J],中国科学. 化学,2017,47(8):926-932 Yu, Haibo,Li, Guli,Zhang, Bei,Zhang, Xinfu,Xiao, Yi,Song, Youtao,Wang, Jieqiong.A neutral pH probe of rhodamine derivatives inspired by effect of hydrogen bond on pKa and its org[J],DYES AND PIGMENTS,2016,133:93-99 Zhang, Ziqian,Wu, Jiayao,Shang, Zhihao,Wang, Chao,Cheng, Jiagao,Qian, Xuhong,Xiao, Yi,Xu, Zhiping,Yang, Youjun.Photocalibrated NO Release from N-Nitrosated Napthalimides upon One-Photon or Two-Photon Irradiati[J],ANALYTICAL CHEMISTRY,2016,88(14):7274-7280 边辉,宋新波,肖义.比例检测活细胞内氧气的动态变化[A],2016,1-1 肖义,王超,宋新波.基于融合蛋白标签的荧光探针[A],2016,1-1 胡明宇,宋新波,李宁,肖义.细胞膜靶向近红外粘度探针[A],2016,1-1 Wang, Junfeng,Bi, Xiaoman,Pang, Yi,Bird, Amanda J.,Dong, Yizhou,Li, Bin,Zhao, Weiyu,Zhang, Xinfu,Luo, Xiao,Corkins, Mark E.,Cole, Sara L.,Wang, Chao,Xiao, Yi,McElroy, Craig A..Two-Photon Near Infrared Fluorescent Turn-On Probe Toward Cysteine and Its Imaging Applications[J],ACS SENSORS,2016,1(7):882-887 Wang, Chao,Song, Xinbo,Han, Zhuo,Li, Xiaoyu,Xu, Yongping,Xiao, Yi.Monitoring Nitric Oxide in Subcellular Compartments by Hybrid Probe Based on Rhodamine Spirolactam[J],ACS CHEMICAL BIOLOGY,2016,11(7):2033-2040 肖义.Near-infrared fluorescent probes with higher quantum yields and neutral pKa values for the evaluatio[J],RSC Advances,2016,6(7):69641-69646 Song, Xinbo,Hu, Mingyu,Wang, Chao,Xiao, Yi.Near-infrared fluorescent probes with higher quantum yields and neutral pK(a) values for the evalu[J],RSC ADVANCES,2016,6(73):69641-69646 Zhang, Jingwen,Wang, Chao,Zhang, Lei,Wu, Huijing,Xiao, Yi,Xu, Yufang,Qian, Xuhong,Zhu, Weiping.Novel nonplanar and rigid fluorophores with intensive emission in water and the application in two[J],RSC ADVANCES,2016,6(75):71624-71627 Chen, Lingcheng,Zhang, Kaichen,Zhu, Linlin,Xiao, Yi.New and Efficient Approach to the Versatile Building Block of 3,4-Perylenedicarboxylic Monoanhydri[J],INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2015,54(50):12699-12703 肖义,张新富.BODIPY类长波长荧光染料的研制与应用[A],2015,1 Cui, Hongxia,Zhao, Hanqing,Wen, Xue,Song, Wenting,Xiao, Yi,Zhao, Yongshan,Fang, Liang.Mechanism of Ion-Pair Strategy in Modulating Skin Permeability of Zaltoprofen: Insight from Molecu[J],JOURNAL OF PHARMACEUTICAL SCIENCES,2015,104(10):3395-3403

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