个人简介
004年毕业于华中科技大学并获学士学位,同年进入国家药品审评中心工作,2010年取得沈阳药科大学硕士学位,2011-2014年就读于北京大学药学院并获得药剂学博士学位,2014-2016年在北京大学基础医学院/美国西南医学中心从事博士后研究;2017年6月入职北京大学基础医学院系统生物医学研究所,现任研究员,博士生导师。2021年获得“北京市杰出青年科学基金”,目前主持/承担国家十三五"重大新药创制"课题、国家自然科学基金、北京市自然科学基金、教育部产学研创新基金、北大医学培育基金等科研项目10项;在 Adv. Mater. , Nat. Commun. , J. Control. Release 等国际著名期刊发表学术论文38篇(其中6篇为杂志封面论文),获得授权专利3项,获得北京市科技进步奖1项
研究领域
1. 生物成像纳米探针
2. 抗肿瘤与抗病毒纳米药物
3. 纳米佐剂与纳米疫苗
近期论文
查看导师新发文章
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1. Sun Y, Gong L, Yin Y, Zhang L, Zhang Q, You F*, Lu D*, Lin Z*. A gradient pH-sensitive polymer-based antiviral strategy via viroporin-induced membrane acidification. Advanced Materials. 2022, 34:1-12 (卷首封论文)
2. Zhu C#, Ma Q#, Gong L, Di S, Gong J, Wang Y, Xiao S, Zhang L, Zhang Q, Fu J*, Lu D*, Lin Z*. Manganese-based multifunctional nanoplatform for dual-modal imaging and synergistic therapy of breast cancer. Acta Biomaterialia. 2022.1.14, S1742-7061(22)00019-8(4)
3. Sun Y, Yin Y, Gong L, Liang Z, Zhu C, Ren C, Zheng N, Zhang Q, Liu H, Liu W, You F, Lu D*, Lin Z*. Manganese nanodepot augments host immune response against coronavirus. Nano Research. 2020, 29: 1-13. (封面论文,被评为“2021年中国卓越科技期刊十大最美封面”)
4. Mei D, Gong L, Zou Y, Yang D, Liu H, Liang Y, Sun N, Zhao L*, Zhang Q*, Lin Z*. Platelet membrane-cloaked paclitaxel-nanocrystals augment postoperative chemotherapeutical efficacy. Journal of Controlled Release. 2020.5.15, 324: 341~353.
5. Zhai Z, Xu P, Yao J, Li R, Gong L, Yin Y*, Lin Z*. Erythrocyte-mimicking paclitaxel nanoparticles for improving biodistributions of hydrophobic drugs to enhance antitumor efficacy. Drug Delivery. 2020, 27(1): 387~399
6. Chen M#, Xiao Z#, Lei X#, Li J, Yu X, Zhang J, Ye G, Guo Y, Mo G, Li C, Zhang Y, Zhang L*, Lin Z*, Fu J*. Preparation, characterization and in vitro–in vivo evaluation of bortezomib supermolecular aggregation nanovehicles. Journal of Nanobiotechnology. 2020,18(57):1-12
7. Fu J#, Li C#, Liu Y#, Chen M, Zhang Q, Yu X, Wu B, Li J, Du L, Dang Y, Wu D, W M*, Lin Z*, Lei X*. The microneedles carrying cisplatin and IR820 to perform synergistic chemo-photodynamic therapy against breast cancer. Journal of Nanobiotechnology. 2020,18(146):1-15
8. Lin Z*, Wang C, Li Y, Li R, Gong L, Su Y, Zhai Z, B X, Di S, Li Z, Dong A, Zhang Q*, Yin Y*. Glutathione-priming nanoreactors enable fluorophore core/shell transition for precision cancer imaging. ACS Applied Materials & Interfaces. 2019, 11(37) : 33667-33675.