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1) Chen B#, Sun L#, Zeng G#, Shen Z#, Wang K#, Yin L#, Xu F, Wang P, Ding Y, Nie Q, Wu Q, Zhang Z, Xia J, Lin J, Luo Y, Cai J, Krausz K, Zheng R, Xue Y, Zheng MH*, Li Y*, Yu C*, Gonzalez FJ*, Jiang CT*. Gut bacteria alleviate smoking-related NASH by degrading gut nicotine. Nature. 2022 Oct;610(7932):562-568.
2) Sun L#, Xie C#, Wang G#, Wu Y#, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang CT*. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin. Nat Med. 2018 Dec;24(12):1919-1929. (Highly cited paper, data from Essential Science Indicators; Commentaries and editorials from Nat Med. 2018, Cell Metab. 2018, Nat Rev Endocrinol. 2018)
3) Zhang X#, Zhang Y#, Wang P#, Zhang SY#, Dong Y, Zeng G, Yan Y, Sun L, Wu Q, Liu H, Liu B, Kong W, Wang X, Jiang CT*. Adipocyte hypoxia-inducible factor 2α suppresses atherosclerosis by promoting adipose ceramide catabolism. Cell Metab. 2019 Nov 5;30(5):937-951.
4) Wu Q#, Liang X#, Wang K#, Lin J, Wang X, Wang P, Zhang Y, Nie Q, Liu H, Zhang Z, Liu J, Pang Y, Jiang CT*. Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis. Cell Metab. 2021 Oct 5;33(10):1988-2003.
5) Wu Q#, Sun L#, Hu X, Wang X, Xu F, Chen B, Liang X, Xia J, Wang P, Aibara D, Zhao S, Zeng G, Yun C, Yan Y, Zhu Y, Bustin M, Zhang SY*, Gonzalez FJ*, Jiang CT*. Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis. J Clin Invest. 2021 May 3;131(9):e142865.
6) Qi X#, Yun C#, Sun L, Xia J, Wu Q, Wang Y, Wang L, Zhang Y, Liang X, Wang L, Gonzalez FJ, Patterson AD, Liu H, Mu L, Zhou Z, Zhao Y, Li R, Liu P, Zhong C, Pang Y*, Jiang CT*, Qiao J*. Gut microbiota-bile acid-interleukin-22 axis orchestrates polycystic ovary syndrome. Nat Med. 2019 Aug;25(8):1225-1233. (Commentaries and editorials from Nat Med. 2019, Cell Metab. 2019, Nat Rev Drug Discov. 2019)
7) Zheng X#, Chen T#, Jiang R#, Zhao A#, Wu Q, Kuang J, Sun D, Ren Z, Li M, Zhao M, Wang S, Bao Y, Li H, Hu C, Dong B, Li D, Wu J, Xia J, Wang X, Lan K, Rajani C, Xie G, Lu A, Jia WP*, Jiang CT*, Jia W*. Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism. Cell Metab. 2021 Apr 6;33(4):791-803. (Highly cited paper, data from Essential Science Indicators)
8) Xie C, Yagai T, Luo Y, Liang X, Chen T, Wang Q, Sun D, Zhao J, Ramakrishnan SK, Sun L, Jiang C, Xue X, Tian Y, Krausz KW, Patterson AD, Shah YM, Wu Y*, Jiang CT*, Gonzalez FJ*. Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis. Nat Med. 2017 Nov;23(11):1298-1308. (Commentaries and editorials from Nat Med. 2017, Nat Rev Gastroenterol Hepatol. 2017)
9) Liu H, Xu F, Gao Y, Pang Y, Xie C*, Jiang CT*. An integrated LC-MS/MS strategy for quantifying the oxidative-redox metabolome in multiple biological samples. Anal Chem. 2020 Jul 7;92(13):8810-8818.
10) Zhang SY, Lv Y, Zhang H, Gao S, Wang T, Feng J, Wang Y, Liu G, Xu MJ, Wang X*, Jiang CT*. Adrenomedullin 2 improves early obesity-induced adipose insulin resistance by inhibiting the class II MHC in adipocytes. Diabetes. 2016 Aug;65(8):2342-2355.