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Q. X. Yang, B. Li, J. Tang, X. J. Cui, Y. X. Wang, X. F. Li, J. Hu, Y. Z. Chen, W. W. Xue, Y. Lou, Y. Q. Qiu*, F. Zhu*. Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data. Brief Bioinform (当年影响因子: 9.101, 生物一区 TOP 期刊). doi: 10.1093/bib/bbz049 (2019).
J. Tang, J. B. Fu, Y. X. Wang, Y. C. Luo, Q. X. Yang, B. Li, G. Tu, J. J. Hong, X. J. Cui, Y. Z. Chen, L. X. Yao, W. W. Xue, F. Zhu*. Simultaneous improvement in the precision, accuracy and robustness of label-free proteome quantification by optimizing data manipulation chains. Mol Cell Proteomics (当年影响因子: 5.236, 生物二区期刊). 18(8): 1683-1699 (2019).
Y. H. Li, X. X. Li, J. J. Hong, Y. X. Wang, J. B. Fu, H. Yang, C. Y. Yu, F. C. Li, J. Hu, W. W. Xue, Y. Y. Jiang, Y. Z. Chen*, F. Zhu*. Clinical trials, progression-speed differentiating features, and swiftness rule of the innovative targets of first-in-class drugs. Brief Bioinform (当年影响因子: 9.101, 生物一区 TOP 期刊). doi: 10.1093/bib/bby130 (2019).
Q. X. Yang, Y. X. Wang, F. C. Li, S. Zhang, Y. C. Luo, Y. Li, J. Tang, B. Li, Y. Z. Chen, W. W. Xue, F. Zhu*. Identification of the gene signature reflecting schizophrenia's etiology by constructing artificial intelligence-based method of enhanced reproducibility. CNS Neurosci Ther (当年影响因子: 3.394, 医学二区期刊). 25(9): 1054-1063 (2019).
J. J. Hong, Y. C. Luo, Y. Zhang, J. B. Ying, W. W. Xue, T. Xie, L. Tao*, F. Zhu*. Protein functional annotation of simultaneously improved stability, accuracy and false discovery rate achieved by a sequence-based deep learning. Brief Bioinform (当年影响因子: 9.101, 生物一区 TOP 期刊). doi: 10.1093/bib/bbz081 (2019).
Y. Zhang, J. B. Ying, J. J. Hong, F. C. Li, T. T. Fu, F. Y. Yang, G. X. Zheng, X. J. Yao, Y. Lou, Y. Q. Qiu, W. W. Xue*, F. Zhu*. How does chirality determine the selective inhibition of histone deacetylase 6? A lesson from Trichostatin A enantiomers based on molecular dynamics. ACS Chem Neurosci (当年影响因子: 4.211, 化学二区 TOP 期刊). 10(5): 2467-2480 (2019).
J. Tang, J. B. Fu, Y. X. Wang, B. Li, Y. H. Li, Q. X. Yang, X. J. Cui, J. J. Hong, X. F. Li, Y. Z. Chen, W. W. Xue, F. Zhu*. ANPELA: analysis and performance-assessment of the label-free quantification workflow for metaproteomic studies. Brief Bioinform (当年影响因子: 9.101, 生物一区 TOP 期刊). doi: 10.1093/bib/bby127 (2019).
Y. H. Li, C. Y. Yu, X. X. Li, P. Zhang, J. Tang, Q. X. Yang, T. T. Fu, X. Y. Zhang, X. J. Cui, G. Tu, Y. Zhang, S. Li, F. Y. Yang, Q. Sun, C. Qin, X. Zeng, Z. Chen, Y. Z. Chen*, F. Zhu*. Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics. Nucleic Acids Res (当年影响因子: 11.561, 生物一区 TOP 期刊). 46(D1): 1121-1127 (2018).
F. Zhu*, X. X. Li, S. Y. Yang, Y. Z. Chen*. The clinical success of drug targets prospectively predicted by the in-silico study. Trends Pharmacol Sci (当年影响因子: 12.797, 医学一区 TOP 期刊). 39(3): 229-231 (2018).
W. W. Xue, F. Y. Yang, P. P. Wang, G. X. Zheng, Y. Z. Chen, X. J. Yao, F. Zhu*. What contributes to serotonin-norepinephrine reuptake inhibitors' dual-targeting mechanism? The key role of transmembrane domain 6 in human serotonin and norepinephrine transporters revealed by MD simulation. ACS Chem Neurosci (当年影响因子: 4.211, 化学二区 TOP 期刊). 9(5): 1128-1140 (2018).
F. Y. Yang, G. X. Zheng, T. T. Fu, X. F. Li, G. Tu, Y. H. Li, X. J. Yao, W. W. Xue*, F. Zhu*. Prediction of binding mode and resistance profile for dual-target pyrrolyl diketo acid scaffold against HIV-1 integrase and reverse-transcriptase associated ribonuclease H. Phys Chem Chem Phys (当年影响因子: 4.123, 化学二区 TOP 期刊). 20(37): 23873-23884 (2018).
Z. J. Han, W. W. Xue, L. Tao, F. Zhu*. Identification of novel immune-relevant drug target genes for alzheimer's disease by combining ontology inference with network analysis. CNS Neurosci Ther (当年影响因子: 3.495, 医学二区期刊). 24(12): 1253-1263 (2018).
B. Li, J. Tang, Q. X. Yang, S. Li, X. J. Cui, Y. H. Li, Y. Z. Chen, W. W. Xue, X. F. Li, F. Zhu*. NOREVA: normalization and evaluation of MS-based metabolomics data. Nucleic Acids Res (当年影响因子: 10.162, 生物一区 TOP 期刊). 45(W1): 162-170 (2017).
P. P. Wang, X. Y. Zhang, T. T. Fu, S. Li, B. Li, W. W. Xue*, X. J. Yao, Y. Z. Chen, F. Zhu*. Differentiating physicochemical properties between addictive and nonaddictive ADHD drugs revealed by molecular dynamics simulation studies. ACS Chem Neurosci (当年影响因子: 4.348, 化学二区 TOP 期刊). 8(6): 1416-1428 (2017).
H. Yang, C. Qin, Y. H. Li, L. Tao, J. Zhou, C. Y. Yu, F. Xu, Z. Chen, F. Zhu*, Y. Z. Chen*. Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information. Nucleic Acids Res (当年影响因子: 9.202, 生物一区 TOP 期刊). 44(D1): 1069-1074 (2016).
F. Zhu, Z. Shi, C. Qin, L. Tao, X. Liu, F. Xu, L. Zhang, Y. Song, X. H. Liu, J. X. Zhang, B. C. Han, P. Zhang, Y. Z. Chen*. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (当年影响因子: 8.026, 生物一区 TOP 期刊). 40(D1): 1128-1136 (2012).
F. Zhu, C. Qin, L. Tao, X. Liu, Z. Shi, X. H. Ma, J. Jia, Y. Tan, C. Cui, J. S. Lin, C. Y. Tan, Y. Y. Jiang*, Y. Z. Chen*. Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting. Proc Natl Acad Sci U S A (当年影响因子: 9.432, 综合性一区 TOP 期刊). 108(31): 12943-12948 (2011).
F. Zhu, B. C. Han, P. Kumar, X. H. Liu, X. H. Ma, X. N. Wei, L. Huang, Y. F. Guo, L. Y. Han, C. J. Zheng, Y. Z. Chen*. Update of TTD: therapeutic target database. Nucleic Acids Res (当年影响因子: 7.479, 生物一区 TOP 期刊). 38(D1): 787-791 (2010).
F. Zhu, L. Y. Han, C. J. Zheng, B. Xie, M. T. Tammi, S. Y. Yang, Y. Q. Wei, Y. Z. Chen*. What are next generation innovative therapeutic targets? Clues from genetic, structural, physicochemical and system profile of successful targets. J Pharmacol Exp Ther (当年影响因子: 3.867, 医学二区 TOP 期刊). 330(1): 304-315 (2009).