个人简介
2009年博士毕业于新加坡国立大学生物工程系,现任职于浙江大学医学院,主要从事细胞微环境控制的研究。利用微细加工制造技术控制原代肝脏细胞微环境,创新建立了体外高通量药物筛选平台装置,已用于和强生公司合作课题研究。利用工程化手段控制胚胎干细胞微环境,建立其体外批量分化的平台。共发表论文12篇,撰写英文专著章节1篇,申请并获批国际专利1项,目前主持国家自然科学基金青年基金项目等课题4项,主要参与5项。获得2009年度和2010年度浙江大学医学院基础医学系优秀博士后奖,2012年浙江大学“求是青年学者”。
近期论文
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1)Shufang Zhang, Yangzi Jiang, Wei Zhang, Longkun Chen, Tong Tong, Wanlu Liu, Hong Wei Ouyang, Xiaohui Zou. Neonatal Desensitization Supports Long Term Survival and Functional Integration of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells in Rat Joint Cartilage without Immunosuppresssion, submitted to Stem Cells and Development, 2012 Aug 14. [Epub ahead of print]..
2)Shufang Zhang, Wenhao Tong, Baixue Zheng, Thomas A Susanto, Lei Xia, Chi Zhang, Abhishek Ananthanaryanan, Xiaoye Tuo, Sakban Rashidah Binte, Rui Rui Jia, Ciprian Iliescu, Kah Hin Chai, Michael McMillian, Shali Shen, Hwa Liang Leo, Hanry Yu, A robust high-throughput sandwich cell-based drug screening platform, Biomaterials, 2011,32(4):1229-41.
3)Shufang Zhang, Yang Zi Jiang, Hong Wei Ouyang, “Cartilage injuries of Women in Sports: the Present and Future Therapeutics”, International Journal of Medical and Biological Frontiers, 2011, 17(6):595-610.
4)Shufang Zhang, Lei Xia, Chiang Huen Kang, Guangfa Xiao, Siew Mine Ong, Yi Chin Toh, Hwa Liang Leo, Danny van Noort, Shyi Herng Kan, Hui Huan Tang and Hanry Yu, Microfabricated silicon nitride membranes for hepatocyte sandwich culture, Biomaterials, 2008, 29(29): 3993-4002
5)章淑芳,章恩明,郑筱祥, 胚体培养对小鼠ES 细胞定向神经分化的影响研究, 生物医学工程学杂志,2006, 23(3): 620-624
6)Zhang Wei, Chen Jialin, Zhang Shufang, Ouyang HongWei, Inhibitory function of parathyroid hormone-related protein on chondrocyte hypertrophy: the implication for articular cartilage repair, Arthritis Res Ther. 2012 Aug 31;14(4):221. [Epub ahead of print].
7)Xia L, Arooz T, Zhang S, Tuo X, Xiao G, Susanto TA, Sundararajan J, Cheng T, Kang Y, Poh HJ, Leo HL, Yu H. Hepatocyte function within a stacked double sandwich culture plate cylindrical bioreactor for bioartificial liver system, Biomaterials. 2012, 33(32):7925-32.
8)Yangzi Jiang, Shufang Zhang, Linlin Wang, Hongwei Ouyang. Cell transplantation for articular cartilage defects: principles of past, present and future practice. Cell Transplantation, 2011, 20(5): 593-607.
9)Siew-Min Ong, Ziqing Zhao, Talha Arooz, Deqiang Zhao, Shufang Zhang, Tiehua Du, Martin Wasser, Danny van Noort and Hanry Yu, Engineering a scaffold-free 3D tumor model for in vitro drug penetration studies, Biomaterials, 2010, 31(6): 1180-1190.
10)Chi Zhang, Ser-Mien Chia, Siew-Min Ong, Shufang Zhang, Yi-Chin Toh, Danny van Noort and Hanry Yu, The Controlled Presentation of TGF-β1 to Hepatocytes in a 3D-Microfludic Cell Culture System, Biomaterials, 2009, 30 (23-24): 3847-3853.
11)Danny van Noort, Siew Min Ong, Chi Zhang, Shufang Zhang, Talha Arooz and Hanry Yu, Stem cells in microfluidics, Biotechnol Prog., 2009, 25(1): 52-60.
12)Enming Zhang, Xiaolong Li, Shufang Zhang, Liangqiang Chen and Xiaoxiang Zheng, Cell cycle synchronization of embryonic stem cells: Effect of serum deprivation on the differentiation of embryonic bodies in vitro, Biochem Biophys Res Commun., 2005, 333(4): 1171-1177.