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研究领域

呼吸药理学、抗炎和免疫药理学(哮喘的神经免疫内分泌调节、COPD分子机制与药物靶点).

近期论文

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1. Zhang SJ, Deng YM, Zhu YL, Dong XW, Jiang JX, Xie QM. Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats. Respir Res. 2010;11: [Epub ahead of print] 2. Zhu YL, Zhang SJ, Deng YM, Dong XW, Jiang JX, Xie QM. Leukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigs. J Neuroinflammation. 2010;7:12. 3. Xie YC, Dong XW, Wu XM, Yan XF, Xie QM. Inhibitory effects of flavonoids extracted from licorice on lipopolysaccharide-induced acute pulmonary inflammation in mice. Int Immunopharmacol. 2009;9(2):194-200. 4. Xie QM, Wu X, Wu HM, Deng YM, Zhang SJ, Zhu JP, Dong XW. Oral administration of allergen extracts from Dermatophagoides farinae desensitizes specific allergen-induced inflammation and airway hyperresponsiveness in rats. Int Immunopharmacol. 2008;8(12):1639-45. 5. Wu X, Zeng LH, Taniguchi T, Xie QM. Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ. 2007;14(10):1792-801. 6. Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY. Effects of ciclamilast, a new PDE 4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur J Pharmacol. 2006;547(1-3):125-35. 7. Sun JG, Deng YM, Wu X, Tang HF, Deng JF, Chen JQ, Yang SY, Xie QM. Inhibition of phosphodiesterase activity, airway inflammation and hyperresponsiveness by PDE4 inhibitor and glucocorticoid in a murine model of allergic asthma. Life Sci.2006;79(22):2077-85. 8. Tang HF, Chen JQ, Xie QM, Zheng XY, Zhu YL, Adcock I, Wang X. The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats. Biochim Biophys Acta. 2006;1762(5):525-32.

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