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个人简介

学术团体和社会兼职: 1994 – 中华医学会内分泌分会 会员 2007 – 中国神经科学会 会员 2008 – 浙江省生理学会 会员 2009- Dutch Neurofederation and Federation of European Neuroscience Society 会员 2012- 浙江大学人文学院意识科学与东方传统研究中心 副主任 2012- Program committee member of The Biennial International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria, started 1992. 学历和研究经历: 1984.09 – 1989.07 安徽医科大学 医学系本科生 1989.07 – 1994.11 安徽医科大学第一附属医院 住院医师(大内科) 1994.12 – 2002.04 安徽医科大学第一附属医院 主治医师(内分泌科) 2002.04 – 2004.02 安徽医科大学第一附属医院 副主任医师(内分泌科) 1994.09 – 1997.07 安徽医科大学 硕士研究生(内科学内分泌与代谢专业) 2000.03 – 2003.06 中国科学技术大学生命科学学院 博士研究生(神经生物学专业) 2002.03 – 2002.11 荷兰皇家科学院脑研究所 Visiting Scholar 2004.02 – 2007.10 荷兰皇家科学院神经科学研究所(原脑研究所) 博士后 2007.10 – 今 浙江大学医学院 教授(神经生物学) PI(神经精神疾病组) 博士生导师

研究领域

1. 神经精神性疾病的神经内分泌学发病机制; 2. 激素与神经递质的生物学节律

近期论文

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1) Shan L, Swaab DF, Bao AM*. Neuronal histaminergic system in aging and age-related neurodegenerative disorders. Exp Gerontol. 2012 Aug 11. [Epub ahead of print] 2) Gao SF, Qi XR, Zhao J, Balesar R, Swaab DF, Bao AM. Decreased nNOS expression in anterior cingulate cortex in depression. Cereb. Cortex (2012, in press) 3)Zhao J, Bao AM, Qi XR, Kamphuis W, Luchetti S, Lou JS, Swaab DF. Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients. J Affect Disord. 2012 May; 138(3): 494-502. 4) Swaab DF, Bao AM, Garcia-Falgueras A, Hofman MA, Ishunina1 TA. Sex differences in the human forebrain. Human Nervous System 3th edition Eds J. Mai and G. Paximos. Academic Press/Elsevier 2012. Chapter 21, 739-758. 5) Bao AM*, Ruhé HG, Gao SF, Swaab DF. Neurotransmitters and neuropeptides in depression. In: Handbook of Clinical Neurology. Vol.105, M.J. Aminoff, Boller,F., Swaab, DF, eds. Elsevier Series edts, and Schlaepfer T.E. and Nemeroff C.B. Volume edts, Amsterdam. 2012, 107-136. 6) Shan L, Hofman MA, van Wamelen DJ, Van Someren EJW, Bao AM*, Swaab DF. Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. Sleep 2012, 35(5): 713-715. 7) Shan L, Bossers K, Unmehopa U, Bao AM*, Swaab DF. Alterations in the histaminergic system in Alzheimer’s disease: a postmortem study. Neurobiol Aging. 33 (2012) 2585-2598 Jan 25. [Epub ahead of print] 8) Shan L, Bossers K, Luchetti S, Balesar R, Lethbridge N, Chazot PL, Bao AM*, Swaab DF. Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study. Neurobiol Aging. 33 (2012) 1488.e1–1488.e13. 9) Shan L, Liu CQ, Balesar R, Hofman MA, Bao AM*, Swaab DF. Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus. Neurobiol Aging. 33 (2012) 1343–1344. 10) Bao AM*, Swaab DF. Sexual differentiation of the human brain: Relation to gender-identity, sexual orientation and neuropsychiatric disorders. Front Neuroendocrinol. 2011 Apr;32(2):214-26. 11) Van Wamelen DJ, Shan L, Aziz NA, Anink JJ, Bao AM, Roos RA, Swaab DF. Functional Increase of Brain Histaminergic Signaling in Huntington's Disease. Brain Pathol. 2011 Jul;21(4):419-27. 12) Bao AM*, Swaab DF. Sex differences in the brain, behavior and neuropsychiatric disorders. Neuroscientist. 2010 Oct;16 (5):550-65. Review. 13) Swaab DF, Bao AM*. (Re-)activation of neurons in aging and dementia: lessons from the hypothalamus. Exp Gerontol. 2011 Feb-Mar; 46(2-3):178-84. Epub 2010 Sep 15. 14) Liu CQ, Shan L, Balesar R, Luchetti S, Van Heerikhuize JJ, Luo JH, Swaab DF, Bao AM*. A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival postmortem human brain tissue. Methods. 2010 Dec; 52(4):359-66. Epub 2010 Jul 16. 15) Bao AM*, Swaab DF. Corticotrophin-releasing hormone and arginine vasopressin in depression: focus on the human postmortem hypothalamus. Vitamins and Hormones, Volume 81- Hormones of the Limbic System. Edt. Gerry Litwack, Academic Press/Elsevier 2010; 82:339-65. 16) Gao SF, Bao AM*. Corticotropin-releasing hormone, glutamate and γ-aminobutyric acid in depression. Neuroscientist 2011;17(1):124-44. 17) Chen XN, Meng QY, Bao AM, Swaab DF, Wang GH, Zhou JN. The Involvement of Retinoic Acid Receptor-alpha in Corticotropin-Releasing Hormone Gene Expression and Affective Disorders. Biol Psychiatry. 2009 Nov 1; 66(9):832-9. Epub 2009 Jul 12. 18) Bao AM*, Lucassen PJ, Swaab DF. The Neuroendocrinology of Psychiatric Disorders. Encyclopedic Reference of Neursocience. Edts. M.d.Binder, N.Hirokawa and U.Windhorst. Springer Verlag 2009, 2641-2645.

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