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个人简介

工作经历 2020.12-至今 浙江大学药学院,教授 2015.10-至今 浙江大学药物安全评价研究中心,常务副主任 2015.03-2016.05 国家药品监督管理总局,药品审评专家 2014.12-2020.12 浙江大学药学院,副教授 2011.07-2014.12 浙江大学药学院,助理研究员 教育经历 2008.12-2010.12 美国University of Texas Southwestern Medical Center at Dallas联合培养 2006.09-2011.06 浙江大学药学院,医学博士 2002.10-2006.06 温州医科大学,理学学士

研究领域

神经免疫药理学 药物毒理及安全性评价 创新药物研发 研究方向为神经免疫学,主要围绕多发性硬化症的髓鞘损伤修复机制和干预策略开展研究,探索调控髓鞘损伤及其免疫微环境中的关键蛋白,发现促进髓鞘修复的潜在治疗手段。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Wang JJ#, Wang JY#, Hong WX#, Zhang LL, Song LQ, Shi Q, Shao YF, Hao GF, Fang CY, Qiu YP, Yang LJ, Yang ZX, Wang JC, Cao J, Yang B, He QJ, Weng Q*. Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling. Nature communications. 2021, Accepted. Weng Q#, Sun H#, Fang C#, Xia F, Liao H, Lee J, Wang J, Xie A, Ren J, Guo X, Li F, Yang B, Ling D*. Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics. Nature Communications. 2021 Mar 4; 12 (1): 1436. Qiu Y, Wang J, Li H, Yang B, Wang J, He Q, Weng Q*. Emerging views of OPTN (optineurin) function in the autophagic process associated with disease. Autophagy. 2021, 1-13. Zhang L#, Tian L#, Dai X#, Yu H#, Wang J#, Lei A, Zhu M, Xu J, Zhao W, Zhu Y, Sun Z, Zhang H, Hu Y, Wang Y, Xu Y, Church GM, Huang H*, Weng Q*, Zhang J*. Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions. Journal of Hematology & Oncology. 2020 Nov 11;13(1):153. Wang JC#, Wang JJ#, Yang LJ#, Zhao C, Wu LN, Xu L, Zhang F, Weng Q*, Michael Wegner & Richard Lu Q*. CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair. Nature Communications. 2020 Aug 17;11(1):4133. Weng Q#, Zhao M#, Zheng J, Yang L, Xu Z, Zhang Z, Wang J, Wang J, Yang B, Richard Lu Q, Ying M*, He Q*. STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia. Cell Death Differ. 2020 Jan; 27(1): 130-145. Weng Q, Wang J, Wang J, Wang J, Sattar F, Zhang Z, Zheng J, Xu Z, Zhao M, Liu X, Yang L, Hao G, Fang L, Lu QR, Yang B, He Q. Correction: Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization. Cell Death Dis. 2020 Feb 7;11(2):108. Weng Q #, Wang JC#, Wang JJ#, He D#, Cheng Z, Zhang F, Verma R, Xu L, Dong X, Liao Y, He X, Potter A, Zhang L, Zhao C, Xin M, Zhou Q, Aronow BJ, Blackshear PJ, Rich JN, He Q, Zhou W, Suvà ML, Waclaw RR, Potter SS, Yu G, Lu QR. Single-cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Cell stem cell. 2019 May 2;24(5):707-723.e8. Weng Q#, Wang JY#, Wang JJ#, Wang J, Sattar F, Zhang Z, Zheng J, Xu Z, Zhao M, Liu X, Yang L, Hao G, Fang L, Lu QR, Yang B*, He Q*. Lenalidomide Regulates Cns Autoimmunity by Promoting M2 Macrophages Polarization. Cell Death & Disease. 2018 Feb 14;9(2):251. Weng Q#, Chen Y#, Wang H, Xu X, Yang B, He Q, Shou W, Chen Y, Higashi Y, van den Berghe V, Seuntjens E, Kernie SG, Bukshpun P, Sherr EH, Huylebroeck D, Lu QR. Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron. 2012 Feb 23;73(4):713-28.

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