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Ying M, Shao X, Jing H, Liu Y, Qi X, Cao J, Chen Y, Xiang S, Song H, Hu R, Wei G, Yang B*, He Q*. Ubiquitin-dependent Degradation of CDK2 Drives the Therapeutic Differentiation of AML by Targeting PRDX2. Blood. 2018 Jun 14;131(24):2698-2711.
Zhu H, Wang D, Yuan T, Yan F, Zeng C, Dai X, Chen Z, Chen Y, Zhou T, Fan G, Ying M, Cao J, Luo P, Liu X, Hu Y, Peng Y, He Q *, Yang B *. Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis. Cancer Research. 2018 Jul 15;78(14):3995-4006.
Luo P*, Xu Z, Li G, Yan H, Zhu Y , Zhu H, Ma S, Yang B*, He Q*. HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport. Autophagy.Accepted.2018
Hong Zhu#,Lin-Lin Chang#,Fang-Jie Yan, Yan Hu, Chen-Ming Zeng, Tian-Yi Zhou, Tao Yuan, Mei-Dan Ying, Ji Cao, He Q *, Yang B*. AKR1C1 Activates STAT3 to Promote the Metastasis of .Non-Small Cell Lung Cancer. Theranostics. 2018; 8(3): 676-692.
Weng Q, Wang J, Wang J, Wang J, Sattar F, Zhang Z, Zheng J, Xu Z, Zhao M, Liu X, Yang L, Hao G, Fang L, Lu QR, Yang B*, He Q*. Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.Cell Death Dis. 2018 Feb 14;9(2):251.
Qian Zhou#, Miao Xian#, Senfeng Xiang, Danyan Xiang, Xuejing Shao, Jincheng Wang, Ji Cao, Xiaochun Yang, Bo Yang, Meidan Ying* and Qiaojun He*. All-trans retinoic acid prevents osteosarcoma metastasis by inhibiting M2 polarization of tumor-associated macrophages. Cancer Immunology Research. 2017
Yangling Li, Miao Xian, Bo Yang, Meidan Ying* and Qiaojun He*. Inhibition of KLF4 by statins reverses Adriamycin-induced metastasis and cancer stemness in osteosarcoma cells. Stem cell reports. 2017.
Miao Xian#, Handi Cao#, Ji Cao, Xuejing Shao, Difeng Zhu, Ning Zhang, Ping Huang,Weixu Li, Bo Yang, Meidan Ying* and Qiaojun He*. Bortezomib sensitizes human osteosarcoma cells to adriamycin-induced apoptosis through ROS-dependent activation of p-eIF2α/ATF4/CHOP axis. International Journal of Cancer. 2017
Xu L, Zhu Y, Shao J, Chen M, Yan H, Li G, Zhu Y, Xu Z, Yang B, Luo P*,He Q *. Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1. British Journal of Cancer. (2017) 1–10
Ying M, Zhang L, Zhou Q , Shao X, Cao J , Zhang N , Li W , Zhu H, Yang B , He Q *. The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα. Oncogene. 2016 January 18; 35, 4358–4367.
Xu Z, Shao J, Li L, Peng X, Chen M, Li G, Yan H, Yang B, Luo P*, He Q*. All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARalpha-mediated DNA damage. BMC cancer 2016 Jan 5;16:2.
Zhang L#, Zhou Q#, Zhang N, Li W, Ying M, Ding W, Yang B*,He Q*. E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα. Cell Cycle. 2014;13(8): 1277-87. doi: 10.4161/cc.28190.4.6
Cai TY, Liu XW, Zhu H, Cao J, Zhang J, Ding L, Lou JS, He Q*, Yang B*. Tirapazamine sensitizes hepatocellular carcinoma cells to topoisomerase I inhibitors via cooperative modulation of hypoxia-inducible factor-1α. Mol Cancer Ther. 2014 Mar;13(3):630-42.
Li Y, Luo P, Wang J, Dai J, Yang X, Wu H, Yang B*, He Q*. Autophagy blockade sensitizes the anticancer activity of CA-4 via JNK-Bcl-2 pathway. Toxicol Appl Pharmacol. 2014 Jan 15;274(2):319-27.
Wu Y, Fu Y, Zheng L, Lin G, Ma J, Lou J, Zhu H, He Q*, Yang B*. Nutlin-3 inhibits epithelial-mesenchymal transition by interfering with canonical transforming growth factor-β1-Smad-Snail/Slug axis. Cancer Lett. 2014 Jan 1;342(1):82-91.
Ying M, Zhou X, Zhong L, Lin N, Jing H, Luo P, Yang X, Song H, Yang B*, He Q*. Bortezomib sensitizes human acute myeloid leukemia cells to all-trans-retinoic acid-induced differentiation by modifying the RARα/STAT1 axis. Mol Cancer Ther. 2013 Feb;12(2):195-206.
Xue T, Luo P, Zhu H, Zhao Y, Wu H, Gai R, Wu Y, Yang B, Yang X*, He Q*. Oxidative stress is involved in Dasatinib-induced apoptosis in rat primary hepatocytes. Toxicol Appl Pharmacol. 2012 Jun 15;261(3):280-91.
Zheng L, Yang W, Zhang C, Ding WJ, Zhu H, Lin NM, Wu HH, He Q*, Yang B*. GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation of Mcl-1. Cancer Lett. 2011 Oct 1;309(1):27-36.
Zhang C, Cai TY, Zhu H, Yang L, Jiang H, Dong XW, Hu Y, Lin NM, He Q*, Yang B*. Synergistic anti-tumor activity of gemcitabine and ABT-737 in vitro and in vivo through disrupting the interaction of USP9X and Mcl-1. Mol Cancer Ther. 2011 Jul;10(7):1264-75.
Zhao Y, Xue T, Yang X, Zhu H, Ding X, Lou L, Lu W, Yang B*, He Q*. Autophagy plays an important role in Sunitinib-mediated cell death in H9c2 cardiac muscle cells. Toxicol Appl Pharmacol. 2010 Oct 1;248(1):20-7.
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