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个人简介

Education: Bachelor (B. Eng)– 2008, Tianjin University, Tianjin, China (Bio. Eng.) Master (M. Eng) – 2010, Tianjin University, Tianjin, China (Biochem. Eng.) Doctorate (Dr. Eng.) – 2013, Tianjin University, Tianjin, China (Biochem. Eng.) Employment: 2020 – Present Associate Professor, Dept. Chem. Eng., Tianjin University 2013 – 2020 Lecturer, Dept. Chem. Eng., Tianjin University 讲授课程: 生物化学 生物化学实验 生物工艺学 生物技术进展 学术成就: 2016年,天津市 “131”创新型人才培养工程第三层次推荐人选 2016年,天津大学北洋学者• 青年骨干教师计划 科研项目: 1.国家自然科学基金面上项目,21878223,智能黏膜穿透纳米马达载药系统的设计及其调控与强化,2019/01-2022/12,主持; 2.国家自然科学基金青年项目,21406160,氧甾酮影响淀粉样蛋白质聚集及其抑制过程的分子机理,2015/01-2017/12,主持; 3.天津市自然科学基金青年项目, 19JCQNJC05200,酸敏感修饰惰性微纳米载药粒子的红外驱动扩散与跨膜传质过程设计与强化,2019/04-2022/03,主持.

研究领域

蛋白质色谱 固定化酶 纳米马达

近期论文

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Y Liu#, L Liu#, Z Qu, L-L Yu*, Yan Sun: Supramolecular assembly of benzophenone alanine and copper presents high laccase-like activity for degradation of phenolic pollutants. Journal of Hazardous Materials, 2023, 433: 130198. L-K Su, K Chen, S Bai, L-L Yu*, Y Sun: Cutinase fused with C-terminal residues of a-synuclein improves polyethylene terephthalate degradation by enhancing the substrate binding. Biochemical Engineering Journal, 2022, 188: 108709. Y Hao, S Bai, L-L Yu*, Y Sun*: Magnetically driven muco-inert Janus nanovehicles for enhanced mucus penetration and cellular uptake. Molecules, 2022, 27: 7291. F Ji, L Liu, L-L Yu*, Y Sun: Effects of Muco-inert and Acid-sensitive Modification on Mucosal Penetration of Nanoparticles. Chemical Journal of Chinese Universities, 2022, 43, 20210837. S Bai, J Zhang, L-Y Zhu, X-X Gong, L-L Yu*, Y Sun: Characterization of a heptapeptide-modified microsphere for oriented antibody immobilization. Journal of Peptide Science, 2022, 28: e3411. X-Q Wang#, Z-F Wang#, L-L Yu, Q-H Shi, X-Y Dong, Y Sun*: Zwitterionic polymer-mediated immobilization of organophosphorus hydrolase enhances hydrolysis of methyl parathion by substrate enrichment. Biochemical Engineering Journal, 2022, 184: 108491. Z-X Li, K Chen, L-L Yu, Q-H Shi, Y Sun*: Fe3O4 nanoparticles-mediated solar-driven PET degradation with PET hydrolase. Biochemical Engineering Journal, 2022, 180: 108344. L-L Yu, Y Sun*: Recent advances in protein chromatography with grafted polymeric ligands. Journal of Chromatography A, 2021, 1638: 461865. L-L Yu#, C-S Li#, Y Liu, Y Sun*: Protein adsorption to poly(2-aminoethyl methacrylate)-grafted Sepharose FF: Effects of chain length and charge density. Journal of Chromatography A, 2021, 1638: 461869. L-L Yu#, R Xu#, X-Y Dong, Y Liu, Y Sun*: Protein adsorption to (3-acrylamido propyl) trimethyl ammonium chloride-grafted Sepharose gel: Charge density reduction via copolymerizing with electroneutral monomer drastically increases uptake rate. Journal of Chromatography A, 2020, 1629: 461843. L-L Yu, Q-H Zhai, Y Sun*: Protein adsorption to poly(ethylenimine)-modified Sepharose FF: VIII. Impacts of surface ion-exchange groups at different polymer grafting densities. Journal of Chromatography A, 2020, 1610: 460538. Y-Y Zhao#, X-X Li#, L-L Yu, X-Y Dong*, Y Sun: Lysozyme adsorption to cation exchanger derivatized by sequential modification of poly(ethylenimine)-Sepharose with succinic anhydride and ethanolamine: Effect of pH and ionic strength. Chinese Journal of Chemical Engineering, 2020, 28: 440–444. D-T Han, S Bai, L-L Gong, L-L Yu*, Y Sun: Effect of counterions on protein adsorption and elution of DEAE-dextran modified Sepharose FF. Chemical Industry and Engineering Progress, 2018, 37 (1): 260–268. Y-Y Zhao#, L-L Yu#, X-Y Dong, Y Sun*: Protein adsorption to poly(ethylenimine)-modified Sepharose FF: VII. Complicated effects of pH. Journal of Chromatography A, 2018, 1580: 72–79. S Bai, L-L Gong, D-T Han, Y-T Li, L-L Yu*, Y Sun: Protein adsorption onto diethylaminoethyl dextran modified anion exchanger: Effect of ionic strength and column behavior. Chinese Journal of Chemical Engineering, 2018, 26: 259–267. Y-Y Zhao, X-Y Dong*, L-L Yu, Y Liu, Y Sun*: Implications from protein adsorption onto anion- and cation-exchangers derivatized by modification of poly(ethylenimine)-Sepharose FF with succinic anhydride. Biochemical Engineering Journal, 2018, 132: 79–89. Y-Y Zhao, X-Y Dong*, L-L Yu, Y Liu, Y Sun*: Characterization of new polymer-grafted protein cation exchangers developed by partial neutralization of carboxyl groups derivatized by modification of poly(ethylenimine)-Sepharose with succinic anhydride. Journal of Chromatography A, 2018, 1550: 28-34.

学术兼职

Biomacromolecules、Scientific Reports、Journal of Chromatography A 、Journal of Separation Science 、Process Biochemistry 、Biochemical Engineering Journal 、 Journal of Chemical & Engineering Data等期刊审稿人

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