贺秉军 - 南开大学 - 生命科学学院

个人简介

教育经历 (1) 1997.9–2000.7, 南开大学, 动物生理生化, 博士 (2) 1994.9–1997.9, 陕西师范大学, 动物生理生化, 硕士 (3) 1990.9–1994.7, 陕西师范大学, 生物教育, 学士工作经历 (1) 2009.11-至今, 南开大学, 生命科学学院, 副教授 (2) 2008.8-2009.10, 美国康奈尔大学, 生命科学学院, 博士后，合作导师:David M. Soderlund (3) 2007.8-2008.8,美国纽约洲立大学布法罗分校, 医学与生物医学科学院, 博士后，合作导师:Glenna Bett (4) 2006.3-2006.9, 美国加州大学, 圣地亚哥分校, 访问学者 (5) 2000.7-2002.11, 南开大学, 生命科学学院, 讲师

研究领域

研究方向为动物生理生化。主要应用膜片钳、电压钳等电生理学方法检测医药、农药对神经细胞和腺细胞等兴奋性细胞以及神经、肌肉在体标本的影响，分析药物作用机理及害虫抗药性机理，并筛选相关药物。目前研究重点是杀虫剂对昆虫神经系统的影响以及害虫抗药性机理分析。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

（1）Guangyan Wu, Lin Li, Bo Chen, Chuan Chen, Duqiang Luo*, Bingjun He*. Natural meroterpenoids isolated from the plant pathogenic fungus Verticillium albo-atrum with noteworthy modification action against voltage-gated sodium channels of central neurons of Helicoverpa armigera. Pesticide Biochemistry and Physiology，2018，144C：91-99 （2）Bingjun He and David M. Soderlund. Effects of the β1 Auxiliary Subunit on Modification of Rat Nav1.6 Sodium Channels Expressed in HEK293 Cells by the Pyrethroid Insecticides Tefluthrin and Deltamethrin. Toxicology and Applied Pharmacology, 2016, （291）：58–69 （3）韩丽鑫，吴广彦，藏媛媛，贺秉军*. 七氟菊酯和溴氰菊酯对棉铃虫神经细胞内钙离子浓度的影响。天津师范大学学报（自然科学版），2015，35（3）：96-101 （4）HE Bing-Jun*, HU Fen, SHANG Xue-Liang, HAN Li-Xin, WU Guang-Yan, LI Jun-Ying, SUN Jin-Sheng*. Molecular Regions Determining the Voltage-dependence of Inactivation for T-type Calcium Channel Cav3.1. Progress in Biochemistry and Biophysics, 2014, 41（9）：877-886 （5）Bingjun He, David M. Soderlund. Functional Expression of Rat Nav1.6 Voltage-Gated Sodium Channels in HEK293 Cells: Modulation by the Auxiliary β1 Subunit.PLoS ONE, 2014, 9(1): e85188 （6）郭直岳，王国红，甄静，贺秉军*. 氯虫酰胺对甜菜夜蛾神经元钠离子通道电流的影响。河南农业科学，2013，42（10）：79-83 （7）Bingjun He, David M. Soderlund. Differential state-dependent modification of rat Nav1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin. Toxicology and Applied Pharmacology.2011，(257) :377–387 （8）赵佳，韩志杰，刘玉杰，纪炳纯，贺秉军*. 昆虫离子通道及其抗药性研究进展。四川动物，2011，30（5）：839-843 （9）Bingjun He, David M. Soderlund. Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Nav1.7 sodium channels.Neuroscience Letters, 2010, (469 ): 268-272 （10）Wang Yong, He Bingjun*, Wu Chunlin, LiuAnxi. Inhibition effects of cyhalothrin on the delayed rectifier potassium current in the central neurons of Helicoverpa armigera. Acta Entomologica Sinica, 2006 , 49 (2) : 235 -240 （11）Yong Wang, Bingjun He*, Qiang Zhao, Zhi Liang and Anxi Liu. Effects of cyhalothrin on the transient outward potassium current in central neurons of Helicoverpa armigera. Insect Science. 2006, 13(1): 13-17 （1）David M. Soderlund*, Jianguo Tan, Bingjun He. Functional reconstitution of rat Nav1.6 sodium channels in vitro for studies of pyrethroid action. NeuroToxicology. 2017, 60:142-149 （2）Tiehong Zhu, Yinxia Wang, Bingjun He, Jingjing Zang, Qing He, Weihua Zhang. Islet amyloid polypeptide acts on glucosestimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca2+ concentration, and insulin secretion. Diabetes/Metabolism Research and Reviews. 2011, 27: 28-34 （3）Dongbo Liu, Bingjun He, Songyan Han, etc. An adsorption behavior of low-density lipoprotein onto cholesterol-modified dextran studied by a quartz crystal microbalance. Materials Science and Engineering C, 27. 2007, 665–669 （4）Qiang Zhao, Deling Kong, Bingjun He, Yanqiang Liu, Xianlin Fan, Anxi Liu. Pertussis toxin modulation of sodium channels in the central neurons of cyhalothrin-resistant and cyhalothrin-susceptible cotton bollworm, Helicoverpa armigera. Insect Science. 2007, 14(2): 107-115