蔡峻 - 南开大学 - 生命科学学院

个人简介

2000年毕业于浙江大学害虫综合治理专业，获博士学位。2000.9～2002.6,在南开大学生物学博士后流动站工作。2007.1～2008.1在丹麦哥本哈根大学分子生物学系访问学习。

研究领域

1）苏云金芽胞杆菌、蜡状芽胞杆菌、枯草芽胞杆菌等生防微生物的杀虫、抗病的分子机理及其相关基因的表达调控。2）苏云金杆菌毒素作用靶标昆虫细胞的结合位点及其导致寄主细胞死亡的分子机理。 3）芽胞杆菌合成生物学。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1 Tong-tong Tan,Xu-dong Zhang,Zhen Miao, Ying Yu, Si-ling Du, Xiao-yue Hou, Jun Cai. A single point mutation in hmgA leads to melanin accumulation in Bacillus thuringiensis BMB181. Enzyme and Microbial Technology. 2019,120:91–97. 2..Kun Jiang, xiaoyue Hou, Lu Han, Tongtong Tan, Zhanglei Cao, Jun Cai *.Fibroblast growth factor receptor, a novel receptor for Bacillus thuringiensis vegetative insecticidal protein Vip3Aa. Toxins. , 2018, 10(12), 546; https://doi.org/10.3390/toxins10120546. 3.Kun Jiang, Xiao-yue Hou, Tong-tong Tan, Zhang-lei Cao, Si-qi Mei, Bing Yan, Jin Chang, Lu Han, Dan Zhao, Jun Cai*. Scavenger receptor-C acts as a receptor for Bacillus thuringiensis vegetative insecticidal protein Vip3Aa and mediates the internalization of Vip3Aa via endocytosis. PLOS Pathogens. 2018，14(10):e1007347，DOI: 10.1371/journal.ppat.1007347 4.Zhang-lei Cao, Tong-tong Tan, Yan-li Zhang, Lu Han, Xiao-yue Hou, Hui-yong Ma，Jun Cai*. NagRBt is a pleiotropic and dual transcriptional regulator in Bacillus thuringiensis. Frontiers in Microbiology, 2018, https://doi.org/10.3389/fmicb.2018.01899 5.Zhang-lei Cao, Tong-tong Tan, Kun Jiang, Si-qi Mei, Xiao-yue Hou, Jun Cai*. Complete genome sequence of Bacillus thuringiensis L-7601, a wild strain with high production of melanin. Journal of Biotechnology .2018, 275(10): 40–43 6.Kun Jiang, Si-qi Mei, Ting-ting Wang, Jin-hua Pan, Yue-hua Chen, Jun Cai*.Vip3Aa induces apoptosis in cultured Spodoptera frugiperda (Sf9) cells. Toxicon, 2016,120 :49-56 7.Yinyue Deng, Jien Wu, Wenfang Yin, Peng Li, Jianuan Zhou, Shaohua Chen, Fei He,Jun Cai, and Lian-Hui Zhang. Diffusible signal factor family signals provide a fitness advantage to Xanthomonas campestris pv. campestris in interspecies competition. Environmental Microbiology, 2016, 18(5)：1534–1545 8.Kun Jiang, Li-na Li, Jin-hua Pan, Ting-ting Wang, Yue-hua Chen, Jun Cai*. YvoA and CcpA Repress the Expression of chiB in Bacillus thuringiensis. Applied and Environmental Microbiology,2015，81（19）:6548-6555 9.Xie Chi Chu, Jin Shi, Hai Yun Jia, Peng Fei Li,Yang Luo, Jun Cai , Yue Hua Chen. Characterization of regulatory regions involved in the inducible expression of chiB in Bacillus thuringiensis. Archives of Microbiology. 2015, 197 (1): 53-63 10.Yingde Shen, Ruibin Liu, Yuehua Chen, Jun Cai*. Identification of an Antifungal Bacillus Strain and Studies on Its Antifungal Active Ingredients. Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012), Lecture Notes in Electrical Engineering. Volume 251, 2014, pp 1637-1644 11.Xiao Liang, Chuan Liu, Xie Chi-chu, Jun Cai* , Yue-hua Chen*. The direct repeat sequence upstream of Bacillus chitinase genes is cis-acting elements that negatively regulate heterologous expression in E. coli. Enzyme and Microbial Technology, 2012,50:280-286. 12.Xie Chi-Chu, Yang Luo, Yue-Hua Chen*, Jun Cai. Construction of a Promoter-probe Vector for Bacillus thuringiensis: the Identification of cis-acting Elements of the chiA Locus. Current Microbiology, 2012,64(5):492-500. 13.Xueyong Zhou, Wei Qi, Jianbo Zhang, Tingting Zou , Guo Chen , Jun Cai*, and Xiang Huang .Spectroscopic investigation of the structure of protoxin protein isolated from Bacillus thuringiensis contacted with minerals. Biocontrol Science and Technology, 2010,20(8)841 – 852 14.Dong Liu, Jun Cai, Chi-chu Xie, Chuan Liu and Yue-hua Chen. Purification and partial characterization of a 36-kDa chitinase from Bacillus thuringiensis subsp. colmeri, and its biocontrol potential. Enzyme and Microbial Technology. 2010,46:252–25646 15.Liang Xiao, Chi-chu Xie, Jun Cai, Zhi-Jie Lin and Yue-Hua Chen. Identification and Characterization of a Chitinase-Produced Bacillus Showing Significant Antifungal Activity. Current Microbiology. 2009 ,58(5):528-33 16.Zhang, J. Cai, J. Deng, Y. Chen, Y. Ren, G. Characterization of Melanin produced by a wild-type strain of Bacillus cereus. Frontiers of Biology in China, 2007. 2: 26～29 17.Jun Cai*, Liang Xiao, Bing Yan, Yinyue Deng, Yuehua Chen, Gaixin Ren.Vip3A is responsible for the potency of Bt9816C culture supernatant against Helicoverpa armigera and Spodoptera exigua. Journal of General and Applied Microbiology. 2006，52（2）83－89 18.Zhong Zhang, Gong-yin Ye, Jun Cai, Cui Hu. Comparative venom toxicity between Pteromalus puparum and Nasonia vitripennis (Hymenoptera: Pteromalidae) toward the hemocytes of their natural hosts, non-target insects and cultured insect cells. Toxicon. 2005, 46(3):337-49 19.Jun Cai*, Rui-Bin Liu, Gai-Xin Ren. The toxicity of Bacillus thuringiensis 9816C to Spodoptera exigua related to the binding sites on BBMV. Insect Science. 2005, 12:429-433 20.Jun Cai, Gong-yin Ye, Cui Hu. Parasitization of Pieris rapae (Lepidopetera) by the pupal endoparisitoid Pteromalus puparum (Hymenoptera: Pteromalidae), suppresses haemocyte encapsulation. Journal of Insect Physiology. 2004,50:315-322