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Ph.D., Medical Physics, University of Wisconsin-Madison, Wisconsin, 2002 M.S., Medical Physics, University of Wisconsin-Madison, Wisconsin, 1999 B.S., Physics, University of Athens, Greece, 1997

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G. Chauhan, H.H.H. Adams, J.C. Bis, G. Weinstein, L. Yu, A.M. T?glhofer, A.V. Smith, S. van der Lee, R.F. Gottesman, R. Thomson, J. Wang, Q. Yang, W.J. Niessen, O.L. Lopez, J.T. Becker, T.G. Phan, R.J. Beare, K. Arfanakis, D. Fleischman, M.W. Vernooij, B. Mazoyer, H. Schmidt, V. Srikanth, D.S. Knopman, C.R. Jack Jr., P. Amouyel, A. Hofman. Association of Alzheimer disease GWAS loci with MRI-markers of brain aging. Neurobiol Aging 2015;36:1765.e7-1765.e16. J.S. Yokoyama, V.E. Sturm, L.W. Bonham, E. Klein, K. Arfanakis, L. Yu, G. Coppola, J.H. Kramer, D.A. Bennett, B.L. Miller, D.B. Dubal. Variation in longevity gene KLOTHO is associated with greater cortical volumes. Annals of Clinical and Translational Neurology 2015;2:215-230. D.A. Fleischman, J. Yang, K. Arfanakis, Z. Arvanitakis, S.E. Leurgans, A.D. Turner, L.L. Barnes, D.A. Bennett, A.S. Buchman. Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology 2015;84:1294-1300. S.D. Han, P.A. Boyle, L. Yu, D.A. Fleischman, K. Arfanakis, S. Leurgans, D.A. Bennett. Financial literacy is associated with medial brain region functional connectivity in old age. Arch Gerontol Geriatr 2014;59:429-438. S. Zhang, K. Arfanakis. White matter segmentation based on a skeletonized atlas: Effects on diffusion tensor imaging studies of regions of interest. J Magn Reson Imaging 2014;40:1189-1198. D.A. Fleischman, S. Leurgans, K. Arfanakis, Z. Arvanitakis, L.L. Barnes, P.A. Boyle, S.D. Han, D.A. Bennett. Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition. Brain Struct Funct 2014;219:2029-2049. R.J. Dawe, D.A. Bennett, J.A. Schneider, S.E. Leurgans, A. Kotrotsou, P.A. Boyle, K. Arfanakis. Ex-vivo T2 relaxation: Associations with age-related neuropathology and cognition. Neurobiol Aging 2014;35:1549-1561. A. Varentsova, S. Zhang, K. Arfanakis. Development of a high angular resolution diffusion imaging human brain template. Neuroimage 2014;91:177-186. Kotrotsou, D.A. Bennett, J.A. Schneider, R.J. Dawe, T. Golak, S.E. Leurgans, L. Yu, K. Arfanakis. Ex-vivo MR Volumetry of Human Brain Hemispheres. Magn Reson Med 2014;71:364-374. S.D. Han, P.A. Boyle, D.A. Fleischman, K. Arfanakis, D.A. Bennett. Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age. Exp Gerontol 2013;48:1489-1498. K. Arfanakis, D.A. Fleischman, G. Grisot, C.M. Barth, A. Varentsova, M.C. Morris, L.L. Barnes, D.A. Bennett. Systemic Inflammation in Non-Demented Elderly Human Subjects: Brain Microstructure and Cognition. PLoS ONE 2013;8:e73107. S.D. Han, A.S. Buchman, K. Arfanakis, D.A. Fleischman, D.A. Bennett. Functional Connectivity Networks Associated With Chronic Musculoskeletal Pain in Old Age. Int J Geriatr Psychiatry 2013;28:858-867. D.A. Fleischman, L. Yu, K. Arfanakis, S.D. Han, L.L. Barnes, Z. Arvanitakis, P.A. Boyle, D.A. Bennett. Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons. Front Aging Neurosci 2013;5:21. S. Zhang, K. Arfanakis. Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging 2013;37:372-381. A.A. Tamhane, K. Arfanakis, M. Anastasio, X. Guo, M. Vannier, J.H. Gao. Rapid PROPELLER-MRI: A combination of iterative reconstruction and under-sampling. J Magn Reson Imaging 2012;36:1241-1247. Z. Arvanitakis, R.L. Brey, J.H. Rand, J.A. Schneider, S.E. Leurgans, L. Yu, A.S. Buchman, K. Arfanakis, D.A. Fleischman, P.A. Boyle, D.A. Bennett, S.R. Levine. Antiphospholipid Antibodies, Brain Infarcts, and Cognitive and Motor Decline in Aging (ABICMA): Design of a Community-Based, Longitudinal, Clinical-Pathological Study. Neuroepidemiology 2013;40:73-84. Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, J.C. Bis, C. Decarli, A.V. Smith, F. van der Lijn, F. Crivello, M. Fornage, S. Debette, J.M. Shulman, H. Schmidt, V. Srikanth, M. Schuur, L. Yu, S.H. Choi, S. Sigurdsson, B.F. Verhaaren, A. L. Destefano, J.C. Lambert, C.R. Jack, M. Struchalin, J. Stankovich, C.A. Ibrahim-Verbaas, D. Fleischman, A. Zijdenbos, T. den Heijer, B. Mazoyer, L.H. Coker, C. Enzinger, P. Danoy, N. Amin, K. Arfanakis, M.A. van Buchem, R.F. de Bruijn, A. Beiser, C. Dufouil, J. Huang, M. Cavalieri, R. Thomson, W.J. Niessen, L.B. Chibnik, G.K. Gislason, A. Hofman, A. Pikula, P. Amouyel, K.B. Freeman, T.G. Phan, B.A. Oostra, J.L. Stein, S.E. Medland, A.A. Vasquez, D.P. Hibar, M.J Wright, B. Franke, N.G. Martin, P.M. Thompson; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, M.A. Nalls, A.G. Uitterlinden, R. Au, A. Elbaz, R.J. Beare, J.C. van Swieten, O.L. Lopez, T.B. Harris, V. Chouraki, M.M. Breteler, P.L. De Jager, J.T. Becker, M.W. Vernooij, D. Knopman, F. Fazekas, P.A. Wolf, A. van der Lugt, V. Gudnason, W.T. Longstreth, M.A. Brown, D.A. Bennett, C.M. van Duijn, T.H. Mosley, R. Schmidt, C. Tzourio, L.J. Launer, M.A. Ikram, S. Seshadri. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet 2012;44:545-552. Y. Wang, J.D. West, L.A. Flashman, H.A. Wishart, R.B. Santulli, L.A. Rabin, N. Pare, K. Arfanakis, A.J. Saykin. Selective Changes in White Matter Integrity in MCI and Older Adults with Cognitive Complaints. Biochim Biophys Acta 2012;1822:423-430. S.D. Han, P.A. Boyle, K. Arfanakis, D.A. Fleischman, L. Yu, E.C. Edmonds, D.A. Bennett. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res 2012;227:233-240. S.D. Han, K. Arfanakis, D.A. Fleischman, S.E. Leurgans, E.R. Tuminello, E. Edmonds, D.A. Bennett. Functional Connectivity Variations in Mild Cognitive Impairment: Associations with Cognitive Function. J Int Neuropsychol Soc 2012;18:39-48. R.J. Dawe, D.A. Bennett, J.A. Schneider, K. Arfanakis. Neuropathologic correlates of hippocampal atrophy in the elderly: A clinical, pathologic, postmortem MRI study. PLoS ONE 2011;6:e26286. S. Zhang, H. Peng, R.J. Dawe, K. Arfanakis. Enhanced ICBM Diffusion Tensor Template of the Human Brain. Neuroimage 2011;54:974-984. D.A. Fleischman, K. Arfanakis, J.F. Kelly, N. Rajendran, A.S. Buchman, M.C. Morris, L.L. Barnes, D.A. Bennett. Regional cortical thinning and systemic inflammation in older persons without dementia. J Am Geriatr Soc 2010;58;1823-1825. A.A. Tamhane, M.A. Anastasio, M. Gui, K. Arfanakis. Iterative image reconstruction for PROPELLER-MRI using the non-uniform fast Fourier transform. J Magn Reson Imaging 2010;32:211-217. K.L. Phan, A. Orlichenko, E. Boyd, M. Angstadt, E.F. Coccaro, I. Liberzon, K. Arfanakis. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry 2009;66:691-694.

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