Xiang, Jialing - Illinois Institute of Technology

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M.D. Xuzhou Medical University Ph.D. University of Alabama at Birmingham

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Zhang H, Lin Y, Manas A, Zhao Y, Denning MF, Ma L, Xiang, J. (2014) Bax?2 promotes apoptosis through caspase-8 activation in microsatellite unstable colon cancer. Mol. Cancer Res. 12(9), 1225-23. Haferkamp, B., Zhang, H., Kissinger, S., Xin, W., Lin, Y., Schultz, M., Xiang, J. (2013) BaxΔ2 family alternative splicing salvages Bax microsatellite-frameshift mutations. Genes & Cancer. 4, 501-512. Yan, J., Xiang, J., Lin, Y., Ma, J., Zhang, J., Zhang, H., Sun, J., Danial, N., Liu, J., Lin, A. (2013). Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation. Cell. 152(1), 304-315. Lin, Y., Lu, Z., Kokontis, J., Xiang, J. (2013). Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression. Biochem. Biophys. Res. Commun. 430(1), 289-93. Haferkamp, B., Zhang, H., Lin, Y., Yeap. X, Bounce, A., Sharpe, J., Xiang, J. (2012). BaxΔ2 is a novel Bax isoform unique to microsatellite unstable tumors. J. Biol. Chem. 287(41), 34722-9. Godfrey, B., Lin, Y., and Xiang, J. (2010). Structure and function analysis of the pro-death domains of androgen receptor in prostate cancer cells. Cell Res. 20: 1138-1140. Tang F, Kokontis J, Lin Y, Liao S, Lin A, Xiang, J. (2009).Androgen via p21 inhibits TNF-alpha-induced JNK activation and apoptosis. J. Biol. Chem. 284(47), 32353-8. Deng, H., Yu, F., Chen, J., Zhao, Y., Xiang, J., Lin, A. (2008). Phosphorylation of bad at Thr201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. J. Biol.Chem. 283(30):20754-60. Lin, Y., Fukuchi, J., Hiipakka, R., Kokontis, J., and Xiang, J. Up-regulation of Bcl-2 is required for the progression of prostate cancer cells from androgen-dependent to androgen-independent growth. Cell Res. 17(6), 531-536 (2007). Lin, Y., Kokontis, J., Tang, F., Liao, S., Lin, A., Chen, C., and Xiang, J. Androgen and Its Receptor AR Promote BAX-mediated Apoptosis. Mol. Cell. Biol. 26(5), 1908 –1916 (2006). Yu, C., Minemoto, Y., Zhang, J., Liu, J., Tang, F., Bui, T., Lin, A.* and Xiang, J*. Activation of the JNK pathway inhibits IL-3 withdrawal induced apoptosis in B-lymphocytes. Molecular Cell. 13, 329-340 (2004). Xiang, J., Gomez-Navarro, J, Arafat, W., Liu B., Barker, S.D., Alvarez, R.D., Siegal G.P., and Curiel, D.T. Pro-apoptotic treatment with an adenovirus encoding bax enhances the effect of chemotherapy in ovarian cancer. J. Gene Medicine 2(2), 97-106 (2000). Xiang, J., Chao, D.T., and Korsmeyer, S.J. Bax-induced cell death may not require interleukin 1 b-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA. 93, 14559-14563 (1996).