Hoerndli, Frederic - Colorado State University - Department of Biomedical Sciences

个人简介

Second Post-doc: University of Utah Imaging, genetic and electrophysiological studies which revealed how molecular motors regulated transport of glutamate receptors to synapses in the lab of Dr. Andres V. Maricq using the genetic model C. elegans. First Post-doc: University of Zurich, Switzerland Whole genome human SNP mapping in the lab of Dr. Andreas Papassotiropoulos, searching for genetic variations associated with improved episodic memory. PhD, Neuroscience, University of Zurich, Switzerland Research on gene network regulation in a cell culture model of Alzheimer's disease, with Dr. Juergen Goetz. MS, Molecular Biology, University of Lausanne, Switzerland

近期论文

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Hoerndli F.J., A. Kallarackal, and A.V. Maricq (2015) Mobile AMPARs are required for synaptic plasticity. Channels(Austin) 9:230-2. Hoerndli F.J., R. Wang, J.E. Mellem, A. Kallarackal, P.J. Brockie, C. Thacker, D.M. Madsen and A.V. Maricq (2015) Neuronal activity and CaMKII regulate kinesin-mediated transport of synaptic AMPARs. Neuron 86: 1-18. (Cited in Faculty 1000) Hoerndli F.J.*, D.A. Maxfield*, P.J. Brockie, J.E. Mellem, E. Jensen, R. Wang, D.M. Madsen and A.V. Maricq (2013) Kinesin-1 regulates synaptic strength by mediating the delivery, removal and redistribution of AMPA receptors. Neuron 80:1421-37. Feature article (*, co-first authors) (Cited in Faculty 1000) Brockie, P.J., M. Jensen, J. Mellem, E. Johnson, R. Wang, D.A. Maxfield, F.J. Hoerndli, D.M. Madsen and A.V. Maricq (2013) Cornichons control ER export of AMPA receptors to regulate synaptic excitability. Neuron 80:129-42. Wang, R., J.E. Mellem, M. Jensen, P.J. Brockie, C.S. Walker, F.J. Hoerndli, D.M. Madsen and A.V. Maricq (2012) The SOL-2/Neto auxiliary protein modulates the function of AMPA-subtype ionotropic glutamate receptors. Neuron 75:838-50. Jensen, M., F.J. Hoerndli, P.J. Brockie, R. Wang, E. Johnson, D. Maxfield, M.M. Francis, D.M. Madsen and A.V. Maricq (2012) Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system. Cell 149:173-87. Stetak, A., F. H?rndli, A.V. Maricq, S. van den Heuvel and A. Hajnal (2009) Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans. PLoS One 4:e6019. Hoerndli, F.J., M. Walser, E. Fr?hli Hoier, D. de Quervain, A. Papassotiropoulos and A. Hajnal (2009) A conserved function of C. elegans CASY-1 calsyntenin in associative learning. PLoS One 4:e4880. Hoerndli, F.J., S. Pelech, A. Papassotiropoulos and J. G?tz (2007) Abeta treatment and P301L tau expression in an Alzheimer’s disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. Eur J Neurosci 26:60-72. Huentelman, M.J., A. Papassotiropoulos, D.W. Craig, F.J. Hoerndli, J.V. Pearson, K.D. Huynh, J. Corneveaux, J. H?nggi, C.R. Modardori, A. Buchmann, E.M. Reiman, K. Henke, D.J. de Quervain and D.A. Stephan (2007) Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Mol Genet 16:1469-77. Papassotiropoulos, A., D.A. Stephan, M.J. Huentelman, F.J. Hoerndli, D.W. Craig, J.V. Pearson, K.D. Huynh, F. Brunner, J. Corneveaux, D. Osborne, M.A. Wollmer, A. Aerni, D. Coluccia, J. H?nggi, C.R. Mondadori, A. Buchmann, E.M. Reiman, R.J. Caselli, K. Henke and D.J. de Quervain (2006) Common Kibra alleles are associated with human memory performance. Science 314:475-78. Hoerndli, F.J., M. Toigo, A. Schild and J. G?tz (2004) Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction. Anal Biochem 335:30-41. Chen, F., M.A. Wollmer, F. Hoerndli, G. Münch, B. Kuhla, E.I. Rogaev, M. Tsolaki, A. Papassotiropoulos and J. G?tz (2004) Role for glyoxalase I in Alzheimer’s disease. Proc Natl Acad Sci USA 101:7687-92. Ferrari, A., F. Hoerndli, T. Baechi, R.M. Nitsch and J G?tz (2003) beta-Amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 278:40162-68. Streffer, J.R., A. Papassotiropoulos, P. Kurosinski, A. Signorell, M.A. Wollmer, M. Tsolaki, V. Iakovidou, F. H?rndli, J. Bosset, J. G?tz, R.M. Nitsch and C. Hock (2003) Saitohin gene is not associated with Alzheimer's disease. J Neurol Neurosurg Psychiatry 74:362-63.