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个人简介

2013 – 至今 副教授 硕士生导师 中山大学 2014 – 至今 广东省动物学会理事 广东省动物学会 2017 – 至今 原生动物学分会理事 中国动物学会 2010 – 2012居里夫人访问学者 英国牛津大学 2011 – 2012 英国STEM大使 Researchers in Residence 2008 – 2010博士后 捷克南波希米亚大学 2003 – 2008博士 中山大学 1999 – 2003 学士 中山大学

研究领域

分子寄生虫学及进化 寄生虫是一类特殊的动物,需要寄生在一个或多个宿主体内。我们不仅研究寄生虫的形态、生活史、感染力、抗药性等基本寄生虫学特征,还研究基因及蛋白功能与进化。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Shen J, Lai DH(共一), Wilson RA, Chen YF, Wang LF, Yu ZL, Li MY, He P, Hide G, Sun X, Yang TB, Wu ZD*, Ayala FJ*, Lun ZR*. (2017) Nitric oxide blocks the development of the human parasite Schistosoma japonicum. Proc. Natl. Acad. Sci. USA. 114 (38): 10214–10219. doi: 10.1073/pnas.1708578114. (影响因子: 9.6) 2017.9.5 2. Hong XK, Zhang X, Fusco OA, Lan YG, Lun ZR, Lai DH*(通讯作者). (2017) PCR-based identification of Trypanosoma lewisi and Trypanosoma musculi using maxicircle kinetoplast DNA. Acta Tropica. 171:207–212. (影响因子: 2.4) 3. Li K, Zhou S, Guo Q, Chen X, Lai DH, Lun ZR, Guo X. (2017) The eIF3 complex of Trypanosoma brucei: composition conservation does not imply the conservation of structural assembly and subunits function. RNA. 23(3):333-345. doi: 10.1261/rna.058651.116. Mar (影响因子: 3.7) 4. Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR, Suo X, Gao N. (2017) Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii. Cell Res. doi: 10.1038/cr.2017.104. (影响因子: 7.3) 5. Xie YT, Gao JM, Wu YP, Tang P, Hide G, Lai DH*(通讯作者), Lun ZR*. (2017) Recombinant α-actinin subunit antigens of Trichomonas vaginalis as potential vaccine candidates in protecting against trichomoniasis. Parasit Vectors. 10(1):83. doi: 10.1186/s13071-017-2009-8. 2017 Feb 16 (影响因子: 3.23) 6. Gao JM, Xie YT, Xu ZS, Chen H, Hide G, Yang TB, Shen JL, Lai DH*(通讯作者), Lun ZR*. Genetic analyses of Chinese isolates of Toxoplasma gondii reveal a new genotype with high virulence to murine hosts. Vet. Parasitol. 241:52–60. doi: 10.1016/j.vetpar.2017.05.007. 2017 Jul 15. (影响因子: 2.5) 7. Qin A, Lai DH(共一), Liu Q, Huang W, Wu Y, Chen X, Yan S, Xia H, Hide G, Lun ZR*, Ayala FJ*, Xiang* AP. (2017) Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii. Proc. Natl. Acad. Sci. USA. 114(6):1365–1370. (影响因子: 9.6) 2017.2.7 8. Wen YZ, Su BX, Lyu SS, Hide G, Lun ZR, Lai DH*. (2016) Trehalose, an easy, safe and efficient cryoprotectant for the parasiticprotozoan Trypanosoma brucei. Acta Tropica 164, 297–302. (影响因子: 2.4) Dec 9. 赖德华,吴娜,谢祎婷,洪晓昆,陈允甫,廖力夫,伦照荣*. (2016)一例输入性皮肤利什曼病病原体的鉴定. 中国寄生虫学与寄生虫病杂志34(3):1-4. [Lai DH, Wu N, Xie YT, Hong XK, Chen YF, Liao LF, Lun ZR*. (2016) Pathogen Identification in an Imported Case of Cutaneous Leishmaniasis. Chin. J. Parasitol. Parasit. Dis. 34(3):295-296.] Jun 国家核心期刊 10. Wen YZ, Lun ZR, Zhu XQ, Hide G, Lai DH*. (2016) Further evidence from SSCP and ITS DNA sequencing support Trypanosoma evansi and Trypanosoma equiperdum as subspecies or even strains of Trypanosoma brucei. Infect. Genet. Evol. 41:56-62. (影响因子: 3.0) July 11. Lai DH*, Hong XK, Su BX, Liang C, Hide G, Zhang X, Yu X, Lun ZR. (2016) Current status of Clonorchis sinensis and clonorchiasis in China. Trans. R. Soc. Trop. Med. Hyg. 110:21–27. (影响因子: 1.8) Jan 12. Lin RH, Lai DH*, Zheng LL, Wu J, Lukeš J, Hide G, Lun ZR* (2015). Analysis of the mitochondrial maxicircle of Trypanosoma lewisi, a neglected human pathogen. Parasit. & Vectors 8:665. (影响因子: 3.4) Dec 13. Lun ZR*, Lai DH, Wen YZ, Zheng LL, Shen JL, Yang TB, Zhou WL, Qu LH, Hide G*, Ayala FJ* (2015) Cancer in the parasitic protozoans Trypanosoma brucei and Toxoplasma gondii. Proc. Natl. Acad. Sci. USA. July 112(29):8835-8842. (影响因子: 9.6) 14. Flegontov P, Michalek J, Janouskovec J, Lai DH, Jirku M, Hajduskova E, Tomcala A, Otto TD, Keeling PJ, Pain A, Obornik M, Lukes J (2015) Divergent Mitochondrial Respiratory Chains in Phototrophic Relatives of Apicomplexan Parasites. Mol. Biol. Evol. May. 32(5): 1115-1131. DOI: 10.1093/molbev/msv021 (影响因子: 10.4) 15. Carnes J, Anupama A, Balmer O, Jackson A, Lewis M, Brown R, Cestari1 I, Desquesnes M, Gendrin C, Hertz-Fowler C, Imamura H, Ivens A, Koreny L, Lai DH, MacLeod A, McDermott SM, Merritt C, Monnerat S, Moon W, Myler P, Phan I, Ramasamy G, Sivam D, Lun ZR*, Lukeš J*, Stuart K*, Schnaufer A* (2015) Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. PLOS Negl. Trop. Dis. 9(1):e3404. (影响因子:4.4) 16. Gao JM, Yi SQ, Wu MS, Geng GQ, Shen JL, Lu FL, Hide G, Lai DH(共同通讯作者), Lun ZR* (2015) Investigation of infectivity of neonates and adults from different rat strains to Toxoplasma gondii Prugniaud shows both variation which correlates with iNOS and Arginase-1 activity and increased susceptibility of neonates to infection. Exp. Parasitol. 149(1): 47–53. (影响因子: 1.6) 17. Xie YT, Lai DH, Liu GY, Zhou JL, Lun ZR* (2015) Severe fever with thrombocytopenia syndrome in China. Lancet Infect. Dis. February 15(2): 145. (影响因子: 22.4) 18. Lun ZR, Wen YZ, Uzureau P, Lecordier L, Lai DH, Lan YG, Desquesnes M, Geng GQ, Yang TB, Zhou WL, Jannin JG, Simarro PP, Truc P, Vincendeau P, Pays E. (2015) Resistance to normal human serum reveals Trypanosoma lewisi as an underestimated human pathogen. Mol. Biochem. Parasitol. 199(1):58-61. (影响因子: 2.9) 19. Lai DH, Poropat E, Pravia C, Landoni M, Couto AS, Pérez Rojo FG, Fuchs AG, Dubin M, Elingold I, Rodríguez JB, Ferella M, Esteva MI, Bontempi EJ*, Lukeš J* (2014) Solanesyl diphosphate synthase, an enzyme of the ubiquinone synthetic pathway, is required throughout the life cycle of Trypanosoma brucei. Euk. Cell Feb 13(2): 320–328. (影响因子: 3.6)

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