Ng, Wai Man (Karno) - California State University, San Marcos - Department of Chemistry and Biochemistry

个人简介

A new method has been developed to measure the specific rotation of optically active compounds using flow injection as a sample introduction system. The laser-based Polarimetry for the detection and identification of chiral molecules was demonstrated by a study of the antibiotic: gentamicin. In addition, the determination of the specific rotation of several different amino acids and the corresponding peptides under different conditions of pH has been accomplished. These results have shown that specific rotation measurements can be used to monitor subtle changes in the structure of a complicated molecule. The use of laser-based polarimeter as a selective detector for optically active compounds has been extended to the detection of achiral compounds. Postdoctoral Training: Department of Pharmacology, Meharry Medical College, Nasville, TN. Doctor of Philosophy: Analytical Chemistry, University of Arkansas, Fayetteville, AR. M.B.A.: Management, Tennessee State University, Nashville, TN. Bachelor of Science (ACS Professional Degree), Summa Cum Laude: Chemistry, Southwestern Oklahoma State University, Weatherford, OK.

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2016 (e–Portfolio) Karno Ng "Incorporation of Virtual Labs and On-line Simulation Activities to an Upper Division General Education Science Course." https://contentbuilder.merlot.org/toolkit/users/babe/virtuallab 2015 (e-Portfolio) Karno Ng "Design of a Fully On-line Introduction General Education Science course with a Hands-on Lab Component." https://contentbuilder.merlot.org/toolkit/users/babe/sanmarcos 2015 Karno Ng, "Development of an On-line General Education Introductory Science Course with a Hands-on Lab Component for Non-science Majors." Journal of Chemical Education. 2015, 20, 1-7. 2011 Todd A. Astorino, Brian J. Martin, Lena Schachtsiek, Keau Wong & Karno Ng. “Minimal Effect of Acute Caffeine Ingestion on Intense Resistance Training Performance.” Journal of Strength and Conditioning Research. 2011 25(6) 1752-1758. 2003 Karno Ng and Sean W. Linder, "HPLC Separation of Tetracycline Analogs: Comparison Study of Laser-based Polarimetric Detection with UV Detection," Journal of Chromatographic Science. 2003, 41, 460-466. 2002 William C. Alston, Karno Ng, "Rapid Colorimetric Screening Test for y-hydroxybutyric acid (Liquid X) in Human Urine," Forensic Science International. 2002, 126, 114-117. 2001 Karno Ng, Ratnasamy Somanathan and Patrick J. Walsh, "Synthesis of Chiral Resolved Pentadentate Sulfonamide-Based Ligands," Tetrahedron Asymmetry, 2001, 12, 1710- 1722. 1999 Karno Ng, Thomas J. Edkins and Donald R. Bobbitt, "Direct Specific Rotation Measurement of Amino Acids, Dipeptides and Tripeptides by Laser-Based Polarimetry," Chirality, 1999, 11, 187-194. 1992 Donald R. Bobbitt and Karno Ng, "Polarization Selective Detection of Biomolecules," Proc. Int. Conf. Lasers (1992), Volume Date 1991, 14th, 808-15. 1992 Donald R. Bobbitt and Karno Ng, "Chromatographic Analysis of Antibiotics in Food Materials, " J. Chromatogr., 1992, 624,153-170. 1992 Donald R. Bobbitt, Faye K. Ogasawara, Yunlong Wang and Karno Ng, "Renewable Optical Fiber Sensors Based on a Dynamically Modified Surface Interaction," SPIE Vol. 1648 Fiber Optic Medical and Fluorescent Sensors and Applications (1992), 227-237. 1991 Karno Ng, Patrick D. Rice, and Donald R. Bobbitt, "Identification and Quantitation of Gentamicin in Milk Using HPLC Separation and Laser-Based Polarimetric Detection," Microchemical Journal., 1991, 44, 25-33.