Duwez, Anne-Sophie - University of Liege

个人简介

Full Professor Head of laboratory

研究领域

The research activities of the group are concerned with AFM-based single molecule force spectroscopy. The expertise covers the development of strategies for the chemical modification of AFM tips and for the chemical coupling between tips and surfaces to detect intra- or inter-molecular forces, and probe individual macromolecules. Tools to probe chemical processes, trigger and control them, and detect the induced mechanical response in situ and in real time are developed. The main research areas are the following: • Molecular recognition between biological (ligands-receptors) or synthetic species and between biological species and surfaces • Mechanochemical properties of (bio)macromolecular systems • Interfacing of molecular machines and investigation of their basic principles • Implementation of classical organic chemical reactions at the single molecule scale on surfaces • Manipulation and transport of molecules, molecule by molecule assembly on surfaces • Ultra-miniaturized chemical sensors The group is member of EMMI, the European Multifunctional Materials Institute (http://www.emmi-materials.eu), which was created in the framework of the FP6 Network of Excellence FAME, and is also partner of European teaching and training programs (Erasmus Mundus master FAME, international Doctoral School IDS-FunMat).

近期论文

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Synthetic oligorotaxanes exert high forces when folding under mechanical load D. Sluysmans, S. Hubert, C. J. Bruns, Z. Zhu, J. F. Stoddart, A.-S. Duwez Nature Nanotechnology 2018, in press (Link) Dynamic force spectroscopy of oligorotaxane foldamers D. Sluysmans, F. Devaux, C. J. Bruns, J. F. Stoddart, A.-S. Duwez Proceedings of the National Academy of Sciences 2017, in press (Link) When ion mobility and molecular dynamics meet to unravel the (un)folding mechanisms of an oligorotaxane molecular switch E. Hanozin, B. Mignolet, D. Morsa, D. Sluysmans, A.-S. Duwez, J. F. Stoddart, F. Remacle, E. De Pauw ACS Nano 2017, 11, 10253-10263 (Link) Force measurements reveal how small binders perturb the dissociation mechanisms of DNA duplex sequences A. Burmistrova, B. Fresch, D. Sluysmans, E. De Pauw, F. Remacle, A.-S. Duwez Nanoscale 2016, 8, 11718–11726 (Link) Liquid-Assisted Plasma-Enhanced Chemical Vapor Deposition of Catechol and Quinone-Functionalized Coatings: Insights into the Surface Chemistry and Morphology R. Mauchauffé, M. Moreno-Couranjou, N. D. Boscher, A.-S. Duwez, P. Choquet Plasma Processes and Polymers 2016, DOI: 10.1002/ppap.201600002 (Link) Fast Atmospheric Plasma Deposition of Bio-Inspired Catechol/Quinone-Rich Nanolayers to Immobilize NDM-1 Enzymes for Water Treatment R. Mauchauffé, S. Bonot, M. Moreno-Couranjou, C. Detrembleur, N. D. Boscher, C. Van De Weerdt, A.-S. Duwez, P. Choquet Advanced Materials Interfaces, 2016, 3, DOI: 10.1002/admi.201500520 (Link)