Pasumarthi, Kishore - Dalhousie University - Department of Pharmacology

研究领域

Dr. Pasumarthi’s research is mainly focused on developing cell based strategies for myocardial repair. Findings from his laboratory suggest that cardiac progenitor cells may be beneficial to replace dead cells after myocardial injury. His laboratory is also developing genetic and pharmacological interventions to promote tissue repair in a diseased heart.

近期论文

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Zhang F, Feridooni T, Hotchkiss A and Pasumarthi KB (2014). Divergent cell cycle kinetics of mid-gestation ventricular cells entail a higher engraftment efficiency after cell transplantation. Am. J. Physiol. Cell Physiol. (In Press). Hotchkiss A, Feridooni T, Zhang F and Pasumarthi KB (2014). The effects of calcium channel blockade on proliferation and differentiation of cardiac progenitor cells. Cell Calcium, 55(5):238-51. Gaspard GJ, MacLean J, Rioux D and Pasumarthi KB (2014). A novel β adrenergic response element regulates both basal and agonist induced expression of cyclin dependent kinase 1 gene in cardiac fibroblasts. Am. J. Physiol. Cell Physiol. 306(6):C540-50. Wafa K, Zhang F, MacLean J and Pasumarthi KB (2013). Characterization of growth suppressive functions of a splice variant of cyclin D2. PLoS ONE 8(1):e53503. Feridooni T, Hotchkiss A, Remley-Carr S, Saga Y and Pasumarthi KB (2011). Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes. PLoS One 6(7):e22801.