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个人简介

B.S. Dalian University of Technology (1996) M.S Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (1999) Ph.D University of Massachusetts, Amherst (2004) Postdoc University of Pennsylvania and Cold Neutron for Biology and Technology (CNBT) at NIST (2004-2007) Assistant Professor, University of California, Berkeley (2007) University of Massachusetts graduate school fellowship (2001) MRS graduate student silver award (2003) 2007 DuPont Science and Technology Grant recipient 2008 3M Nontenured Faculty Award recipient 2008 DuPont Young Professor Award recipient 2009 ONR-Young Investigator Award recipient Named as one of “Brilliant 10” by Popular Science Magazine in 2009 2010 Li Ka Shing Woman Research Award recipient 2011 Camille-Dreyfus Scholar-Teacher Award recipient 2011 ACS Arthur K. Doolittle Award recipient

研究领域

The key to future technology is the design and fabrication of functional materials having structures ordered down to the molecular level. This goal can't be reached by conventional "top-down" approaches and remains as the "holy grail" using synthetic materials such as block copolymers. In addition, there have been limitations in the functionalization of these nanostructured materials. On the other hand, nature has made a dizzying array of materials using a few building blocks. Remarkable progress has been made in de novo protein design and various peptides have been designed with well-defined structure-sequence relationship and are able to mimic or exceed natural protein functions with much more simple, yet robust, structures. Researches in Xu's group take advantage of the recent developments in de novo protein design and peptidomimetics, polymer science and nanoparticles synthesis and manipulation, and use designed peptides and proteins in concert with the self-assembly of block copolymers, conjugated molecule and nanoparticles as platforms to generate nanostructured materials. Her group aims to generate hierarchical structures spanning multi-length scales down to few nanometers with built-in biological, electrical and magnetic functionalities. Her research group focuses on a fundamental understanding of the physics of assemblage on multiple length scales leading to the design and assembly of functional thin films with tailored functionalities.

近期论文

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Single-chain heteropolymers transport protons selectively and rapidly T. Jiang, A. Hall, M. Eres, Z. Hemmatian, B. Qiao, Y. Zhou, Z. Ruan, A. D. Couse, W. T. Heller, H. Huang, M. Olvera de la Cruz, M. Rolandi & T. Xu in Nature Jan 08 2020 Diffusive Flux Analysis of Tumor Vascular Permeability for 3-Helix-Micelles in Comparison to Other Nanoparticles M. Lim, V. Dharmaraj, B. Gong, T. Xu in BioRxiv Jul 23 2019 Diffusion-Dependent Nanoparticle Assembly in Thin Films of Supramolecular Nanocomposites J. Huang, Y. Qian, K. Evans, T. Xu in Macromolecules Jul 23 2019 Sorption-Enhanced Mixed Matrix Membranes with Facilitated Hydrogen Transport for Hydrogen Purification and CO2 Capture L. Zhu, D. Yin, Y. Qin, S. Konda, S. Zhang, A. Zhu, S. Liu, T. Xu, M. Swihart, H. Lin in Advanced Functional Materials Jul 08 2019 Organic Nanotube with Subnanometer, pH-Responsive Lumen S. Darnall, C. Li, M. Dunbar, M. Alsina, S. Keten, B. Helms, T. Xu in Journal of the American Chemical Society Jun 25 2019 Redox degradable 3-helix micelles with tunable sensitivity Y. Xue, B. Jung, T. Xu in Peptide Science May 17 2019 Tailoring Co-assembly of Nanodiscs and Block Copolymer-Based Supramolecules by Manipulating Interparticle Interactions S. Hsu, T. Xu in Macromolecules Apr 1 2019 45% Periodicity Reduction in Nanocomposite Thin Films via Rapid Solvent Removal J. Huang, X. Chen, P. Bai, R. Hai, C. Sun, T. Xu in Macromolecules Feb 12 2019 Self-Assembly of Supramolecular Thin Films: Role of Small Molecule and Solvent Vapor Annealing K.Evans, T. Xu in Macromolecules Dec 31 2018 Practical Prediction of Heteropolymer Composition and Drift A. A. A. Smith , A. Hall , V. Wu, T. Xu in ACS Macro Letters Dec 19 2018 Reusable Enzymatic Fiber Mats for Neurotoxin Remediation in Water C. DelRe, C. Huang, T.Li, P. Dennis, E. Drockenmuller, T. Xu in ACS Applied Materials & Interfaces Dec 3 2018 Random heteropolymers preserve protein function in foreign environments B. Panganiban, B. Qiao, T. Jiang, C. DelRe, M. M. Obadia, T. D. Nguyen, A. A. A. Smith, A. Hall, I. Sit, M. G. Crosby, P. B. Dennis, E. Drockenmuller, M. Olvera de la Cruz, T. Xu in Science Mar 16 2018 Diversifying Nanoparticle Assemblies in Supramolecule Nanocomposites Via Cylindrical Confinement P. Bai, S. Yang, W. Bao, J. Kao, K. Thorkelsson, M.B. Salmeron, X. Zhang, T. Xu in Nano Letters Oct 2 2017 Controlling Styrene Maleic Acid Lipid Particles through RAFT A.A.A. Smith, H.E. Autzen, T. Laursen, V. Wu, M. Yen, A. Hall, S.D. Hansen, Y. Cheng, T. Xu in Biomacromolecules Sep 21 2017 Sub-20 nm Stable Micelles Based on a Mixture of Coiled-Coils: A Platform for Controlled Ligand Presentation J. Ang, D. Ma, B.T. Jung, S. Keten, T. Xu in Biomacromolecules Dec 3 2017 Preventing Thin Film Dewetting via Graphene Capping P. Cao, P. Bai, A. A. Omrani, Y. Xiao, K. L. Meaker, H.-Z. Tsai, A. Yan, H. S. Jung, R. Khajeh, G. F. Rodgers, Y. Kim, A. S. Aikawa, M. A. Kolaczkowski, Y. Liu, A. Zettl, K. Xu, M. F. Crommie, T. Xu in Advanced Materials Jul 19 2017 Achieving 3-D Nanoparticle Assembly in Nanocomposite Thin Films via Kinetic Control J. Huang, Y. Xiao, and T. Xu in Macromolecules Mar 3 2017 Kinetic Pathway of 3-Helix Micelle Formation J. Ang, B.T. Jung, H. Dong, and T. Xu in Biomacromolecules Feb 6 2017 Understanding Peptide Oligomeric State in Langmuir Monolayers of Amphiphilic 3-Helix Bundle-forming Peptide-PEG Conjugates R. Lund, J. Ang, J.Y. Shu, and T. Xu in Biomacromolecules Oct 26 2016 Internal Structure of 15 nm 3-Helix Micelle Revealed by Small-Angle Neutron Scattering and Coarse-Grained MD Simulation J. Ang, D. Ma, R. Lund, S. Keten, and T. Xu in Biomacromolecules Sep 1 2016 Nanorod-Based Supramolecular Nanocomposites: Effects of Nanorod Length K. Thorkelsson, N. Bronstein, and T. Xu in Macromolecules Aug 30 2016 Ionic Liquids Containing Block Copolymer Based Supramolecules S. Liu and T. Xu in Macromolecules Aug 3 2016

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