Co-Director, FQRNT Centre for Green Chemistry and Catalysis
Fellow of the Royal Society of Canada (Academy of Science)
Fellow of the American Association for the Advancement of Sciences (AAAS)
Fellow of the American Chemical Society (ACS)
Fellow of the Royal Society of Chemistry (UK)
Fellow of the Chemical Institute of Canada (CIC)
Fellow of the World Academy of Sciences (TWAS)
B. Sc. (Zhengzhou University, 1983)
M.S. (Chinese Academy of Sciences, 1988)
Ph. D. (McGill University, 1992)
NSERC Postdoctoral Fellow (Stanford University, 1992-94)
Visiting Faculty, UC Berkeley (2002)
Professor (Assistant, Associate, Full) (Tulane University, 1994-2003)
(US) NSF CAREER Award, 1998-2002
Outstanding Young Oversea Scientist Award (NSFC), 2001
(US) Presidential Green Chemistry Challenge Award (Academic), 2001
Japan Society for Promotion of Science (Senior) Fellow, 2002
Honorary Research Professor (Chemistry Institute, Chinese Academy of Science)
Canadian Green Chemistry and Engineering Award (individual), 2010
Award of Merit, Federation of the Chinese Canadian Professionals (ont), 2011
R. U. Lemieux Award (CSC), 2015
Alfred Bader Award (CSC), 2018
Killam Fellow of the Canadian Council of Arts (2018)
Catalysis Award (CIC, 2020)
Humboldt Research Award (2021)
1. Green Chemistry:
Explore new catalytic reactions that have high atom-efficiency in water and other cleaner media (CO2 and Ionic Liquids), and to transform these reactions into general synthetic tools for synthesizing biologically important compounds and organic materials in a cost-effective and environmentally friendly manner.
C-C bond formations via catalytic C-H and C-X activation
Catalytic cyclization reactions
Catalytic asymmetric reactions
Catalytic functionalization of renewable materials.
2. Synthesis of biologically active compounds:
Developing new methods for synthesizing natural products and other biologically important compounds. One special interest is to develop synthesis and study of "Chemical Sensitizers" for targeted cancer therapy.
Kan, J; Chen, Z; Qiu, Z; Lv, L; Li, C.-C.; Li, C.-J., Umpolung carbonyls enable direct allylation and olefination of carbohydrates. Sci. Adv. 2022, 8. DOI: 10.1126/sciadv.abm6840
Luo, S.; Peng, M.; Querard, P.; Li, C.-C.; Li, C.-J., Copper-Catalyzed Conjugate Addition of Carbonyls as Carbanion Equivalent via Hydrazones. J. Org. Chem 2021, 86, 13111.
Dai, X.-J.#; Li, C.-C. #; Li, C.-J.*, Carbonyl umpolung as an organometallic reagent surrogate. Chem. Soc. Rev. 2021
Castillo-Pazos, D.#; Lasso, J.#; Li, C.-J., Modern methods for the synthesis of perfluoroalkylated aromatics. Org. Biomol. Chem., 2021,19, 7116-7128.
Lasso, J.#;Castillo-Pazos, D.#; Li, C.-J., Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions. Chem. Soc. Rev. 2021,50, 10955-10982.
Cao, D.; Li, C.-C.; Zeng, H.; Peng, Y.; Li, C.-J., C(sp3)− C(sp3) bond formation via nickel-catalyzed deoxygenative homo-coupling of aldehydes/ketones mediated by hydrazine. Nat. Commun. 2021, 12, 3729–3736.
Lv, L.; Li, C.-J., Ruthenium catalyzed β-selective alkylation of vinylpyridines with aldehydes/ketones via N2H4 mediated deoxygenative couplings. Chem. Sci. 2021, 12, 2870-2875.
Lv, L.; Li, C.-J., Palladium-catalyzed defluorinative alkylation of gem–difluorocyclopropanes: switching regioselectivity via simple hydrazones. Angew. Chem. Int. Ed. 2021, 60, 13098–13104.
Li, J.#; Huang, C.-Y.#; Li, C.–J.*, Deoxygenative Functionalizations of Aldehydes, Ketones and Carboxylic Acids. Angew. Chem. Int. Ed. 2021, DOI: https://doi.org/10.1002/anie.202112770
Li, J.#; Huang, C.-Y.#; Han, J.-T.; Li, C.–J.*, Development of a quinolinium/cobaloxime dual photocatalytic system for oxidative C–C cross-couplings via H2 release. ACS Catal. 2021, 11, 14148-14158
Li, J.#; Huang, C.-Y.#; Ataya, M.#; Khaliullin, R.Z.*; Li, C.–J.*, Direct deoxygenative borylation of carboxylic acids. Nat. Commun. 2021, 12, 4970-4978
Huang, C.-Y.#; Li, J.#; Li, C.-J., A cross-dehydrogenative C(sp3)−H heteroarylation via photo-induced catalytic chlorine radical generation. Nat. Commun. 2021, 12, 4010-4018.
Li, C.-C.; Wang, H.; Sim, M. M.; Qiu, Z.; Chen, Z.-P.; Khaliullin, R. Z.; Li, C.-J., Empowering alcohols as carbonyl surrogates for Grignard-type reactions. Nat. Commun, 2020, 11, 6022.
Ung. S. P.-M.; Mechrouk, V. A.; Li, C.-J. Shining Light on the Light-Bearing Element: A Brief Review of Photomediated C–H Phosphorylation Reactions. 2020, 10.1055/s-0040-1705978
Qiu, Z.; Zeng, H.; Li, C.-J.Coupling without Coupling Reactions: En Route to Developing Phenols as Sustainable Coupling Partners via Dearomatization–Rearomatization Processes. Acc. Chem. Res. 2020, 53, 10, 2395-2413.
Lang, Y.; Li, C.-J.; Zeng, H. Dearomatization-Rearomatization Strategy for Palladium-Catalyzed C–N Cross-Coupling Reactions. Synlett. 2020, 00, 0000-0000. (Invited article for special issue for Prof. B. M. Trost’s 80th Birthday)
Li, J.; Wang, H.; Qiu, Z.; Huang, C.-Y.; Li, C.-J. Metal-Free Direct Deoxygenative Borylation of Aldehydes and Ketones. J. Am. Chem. Soc. 2020, 142, 13011-13020.
Cao, D.; Chen, Z.; Lv, L.; Zeng, H.; Peng, Y.; Li, C.-J. Light-Driven Metal-Free Direct Deoxygenation of Alcohols Under Mild Conditions. iScience. 2020, 23, 101419-101429.
Liu, M.; Tan, L.; Rashid, R. T.; Cen, Y.; Cheng, S.; Botton, G.; Mi, Z.; Li, C.-J. GaN Nanowire as a Reusable Photoredox Catalyst for Radical Coupling of Carbonyl Under Blacklight-Irradiation. Chem. Sci. 2020, 11, 7864-7870.
Kim, Y.; Li, C.-J. Perspectives on Green Synthesis and Catalysis. Green Chem. Catal. 2020, 1, 1-11.
Dou, Q.; Li, C.-J.; Zeng, H. Photoinduced Transition-Metal- and External-Photosensitizer-Free Intramolecular Aryl Rearrangement via C(Ar)–O Bond Cleavage. Chem. Sci. 2020, 11, 5740-5744.