个人简介

Education Ph.D., Biomedical Engineering Northwestern University (2003-2008) B.S.. Biological Sciences, KAIST (1993-1997) Career 2008-2009 Post Doc.. Chemical Engineering, MIT 2007-1998 Researcher, Department of Biological Sciences, KAIST 2000-2002 Researcher, Department of Biological Sciences, KAIST 2002-2003 Researcher, University of Chicago Awards 2008 Top 100 Science Stories, Discover Magazine 2007 Future Scientist Award 2007 NASA Inventor Award 2007 Graduate Student Award, Materials Research Society 2007 Richard W. Jones Best Poster Award

研究领域

Biomedical Engineering

We are interested in biomimetics which is the application of systems found in nature to the study and design of engineered systems. Recently we are developing a novel adhesive for biomedical applications inspired by the mussel adhesive molecules known to possess powerful adhesion capability even in the presence of water. This has a lot of potentials for application such as medical bio-adhesive, drug delivery, surface modification for cell therapy, super hydrophobic/hydrophilic surface and so on. Research topics - Generalized strategy for functionalization of any material surfaces inspired by mussel adhesion - Adhesive anti-bacterial, anti-fungal compounds - Nanoparticle synthesis - Protein therapeutics - Development of synthetic gecko adhesives - Biointerphases

近期论文

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Seongwoo Ryu, Jeffrey B. Chou, Kyueui Lee, Dongju Lee, Soon Hyung Hong, Rong Zhao, Haeshin Lee, Sang-gook Kim"Direct insulation-to-conduction transformation of adhesive catecholamine for simultaneous increases of electrical conductivity and mechanical strength of CNT fiber"Adv. Mater. 2015 accepted. K. Kim, K. Kim, J. H. Ryu, Haeshin Lee “Chitosan-Catechol: A Polymer with Long-lasting Mucoadhesive Properties” Biomaterials 2015 accepted. Sang Hyeon Hong, M. Shin, J. Lee, J. H. Ryu, S. Lee, J. W. Yang, W. D. Kim, Haeshin Lee, “STAPLE: stable alginate gel prepared by linkage exchange from ionic to covalent bonds” Adv. Healthcare Mater. 2015 accepted. Doi : 10.1002/adhm.201400833 Keumyeon Kim M. Shin, M-Y Koh, J. H. Ryu, M. S. Lee, S. Hong, Haeshin Lee “TAPE: a medical adhesive inspired by a ubiquitous compound in plants” Adv. Funct. Mater. 2015 accepted. Doi : 10.1002/adfm.201500034 H.-J. Park, K. Yang, M. -J. Kim, J. Jang, M. Lee, D. -W. Lee, H. Lee*, S. -W. Cho*, "Bio-inspired oligovitronectin-grafted surface for enhanced self- renewal and long-term maintenance of human pluripotent stem cells under feeder-free conditions", Biomaterials 2015, in press doi : 10.1016/j.biomaterials.2015.01.015 Shin, M., Ryu, J. H., Park, J. P., Kim, K., Yang, J. W. and Lee, H. (2015), DNA/Tannic Acid Hybrid Gel Exhibiting Biodegradability, Extensibility, Tissue Adhesiveness, and Hemostatic Ability. Adv. Funct. Mater.. doi : 10.1002/adfm.201403992 S. M. Kang, H. Lee, "One-Step Immobilization of Initiators for Surface-Initiated ROP and ATRP by Poly(norepinephrine) Coating" J. Nanosci. Nanotechnol. 2015, 15(2), 1597-1600 doi : 10.1166/jnn.2015.9284 J.P. Park, I.T. Song, J. Lee, J.H. Ryu, Y. Lee, H. Lee. "Vanadyl-Catecholamine Hydrogels Inspired by Ascidians and Mussels" Chem. Mater., 2015, 27, 105-111. doi : 10.1021/cm503425d J. M. Lee, J. H. Ryu, E. A. Kim, S. Jo, B-S. Kim, H. Lee*. G-I. Im*, Adhesive barrier/directional controlled release for cartilage repair by endogenous progenitor cell recruitment, Biomaterials, 2014, in press doi : 10.1016/j.biomaterials.2014.11.006 S. Ryu. Y. Kim, Haeshin Lee*, S. H. Hong* “Dry Spun 3D Woven Carbon Nanotube Anode Electrode for Li-Ion Batteries” J. Nanotech. Nanosci. 2014, 14, 9152-57 doi : 10.1166/jnn.2014.10099 E. H. Jeong, J. H. Ryu, H. Jeong, B. Jang, H. Y. Lee, S. Hong, Haeshin Lee and H. Lee*, Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells, Chem. Commun., 2014,50, 13388-13390 doi : 10.1039/C4CC07155G Ji Hyun Ryu, Seongyeon Jo, Mi-Young Koh, Haeshin Lee*, Bio-Inspired, Water-Soluble to Insoluble Self-Conversion for Flexible, Biocompatible, Transparent, Catecholamine Polysaccharide Thin Films, Adv. Func. Mater. 2014, in press. doi : 10.1002/adfm.201402250 Joseph P. Park, Minjae Do, Hyo-Eon Jin, Seung-Wuk Lee*, and Haeshin Lee*, "M13 Bacteriophage Displaying DOPA on Surfaces: Fabrication of Various Nanostructured Inorganic Materials without Time-Consuming Screening Processes", ACS Appl. Mater. Interface, 2014, 6 (21), 18653-18660 doi : 10.1021/am506873g Mihyun Lee, Kisuk Yang, Yong Hwa Hwang, Youngro Byun, Dong Yun Lee, Seung-Woo Cho, and Haeshin Lee*, "Spheroform: Therapeutic Spheroid-Forming Nanotextured Surfaces Inspired by Desert Beetle Physosterna cribripes", Adv. Health. Mat, 2014, in press. doi : 10.1002/adhm.201400429 Seongwoo Ryu, Kyueui Lee, Soon Hyung Hong, and Haeshin Lee*, "Facile Method to Sort Graphene Quantum Dot by Size through Ammonium Sulfate Addition", RSC Advances, 2014, 4, 56848-52 doi : 10.1039/C4RA07032A Inseong You, Tae Geol Lee, Yoon Sung Nam, Haeshin Lee*, "Fabrication of a Micro-omnifluidic Device by Omniphilic/Omniphobic Patterning on Nanostructured Surfaces", ACS Nano, 2014 accepted. doi : 10.1021/nn502226v Seonki Hong, C. F. Schaber, K. Dening, E. Appel, Stanislav N. Gorb, Haeshin Lee* “Air/Water Interfacial Formation of Freestanding, Stimuli-Responsive, Self-Healing Catecholamine Janus-Faced Microfilms” Adv. Mater. 2014, 26(45), 7581-7587 doi : 10.1002/adma.201403259 C. Yang, X. Ding, R. J. Ono, Haeshin Lee, L. Y. Hsu, J. Hedrick, Yi Yan Yang, “Brush-Like Polycarbonates Containing Dopamine, Cations, and PEG Providing a Broad-Spectrum, Antibacterial, and Antifouling Surface via One-Step Coating” Adv. Mater. 2014, 26, 7346-51 doi : 10.1002/adma.201402059 Seonki Hong, Hyukjin Lee, Haeshin Lee* “Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions” Beilstein J. Nanotech. 2014, 5, 887-894 doi : 10.3762/bjnano.5.101 E. Kim, S. Lee, S. Hong, G. Jin, M. Kim, K. I. Park, Haeshin Lee*, Jae-Hyung Jang* “Sticky ‘delivering-from’ strategies using viral vectors for efficient hyman neural stem cell infection by bioinspired catecholamines” ACS. Appl. Mater. & Interfaces 2014, 6, 8288-94 (June 11) doi : 10.1021/am5011095