曾华强 - 福州大学

研究领域

长期以来专注于发展通道蛋白的人工版本即人工跨膜输运体将通道蛋白的复杂结构简单化、单一功能多样化、稳定化、应用化。具体来说，结合超分子化学和生物学的原理，聚焦于具有新颖结构和独特功能的新型仿生人工跨膜运输体的构筑及在海水淡化，第三代单分子基因测序技术和抗癌新药开发中的应用。

近期论文

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K. H. Lee, H. Zeng, "A General Double Library SELEX Strategy for Aptamer Selection Using Unmodified Nonimmobilized Targets," Analytical and Bioanalytical Chemistry, 409 (2017), 5081-5089 J. Shen, C. L. Ren and H. Q. Zeng, "Surprisingly High Selectivity and High Affinity in Mercury Recognition by H-Bonded Cavity-Containing Aromatic Foldarands," Journal of the American Chemical Society, 139 (2017) 5387-5396 C. L. Ren, J. Shen, F. Chen and H. Q. Zeng, "Rapid Room-Temperature Gelation of Crude Oils by a Wetted Powder Gelator," Angew. Chem., Int. Ed., 56 (2017) 3847-3851 H. Zhao, J. Shen, C. Ren, W. Zeng and H. Zeng, "A Foldamer-Based Organocatalyst for Direct Arylations of Unactivated Arenes," Organic Letters, 19 (2017) 2190-2193 Y. P. Huo and H. Q. Zeng, "“Sticky”-Ends-Guided Creation of Functional Hollow Nanopores for Guest Encapsulation and Water Transport," Accounts of Chemical Research, 49 (2016) 922-930 C. L. Ren, G. H. B. Ng, H. Wu, K.-H. Chan, J. Shen, C. Teh, J. Y. Ying and H. Q. Zeng, "Instant Room-Temperature Gelation of Crude Oil by Chiral Organogelators," Chem. Mater., 28 (2016) 4001-4008 J. Shen, C. L. Ren and H. Q. Zeng, "Tuning Cation-Binding Selectivity and Capacity Via Side Chain-Dependent Molecular Packing in the Solid State," Chemical Communications, 52 (2016) 10361-10364 Y. P. Huo, H. Q. Zeng and Y. G. Zhang, "Integrating Metabolic Engineering and Heterogeneous Chemocatalysis: New Opportunities for Biomass to Chemicals," ChemSusChem, 9 (2016) 1078-1080 C. Ren, F. Chen, F. Zhou, J. Shen, H. Su and H. Zeng, "Low-Cost Phase-Selective Organogelators for Rapid Gelation of Crude Oils at Room Temperature," Langmuir, 32 (2016) 13510-13516 W.-J. Meng, J. Xiong, W.-X. Wang, H.-Y. Zhang, H. Zeng and J.-F. Hu, "Phlefargesiine A, a C16N2 Lycopodium Alkaloid with an Unprecedented [6/7/6/6]-Tetracyclic Skeleton from Phlegmariurus Fargesii," Tetrahedron Letters, 57 (2016) 3218-3221 C. Li, L. Wu, L. Chen, X. Yuan, Y. Cai, W. Feng, N. Liu, Y. Ren, A. Sengupta, M. S. Murali, P. K. Mohapatra, G. Tao, H. Q. Zeng, S. Ding and L. Yuan, "Highly Efficient Extraction of Actinides with Pillar[5]Arene-Derived Diglycolamides in Ionic Liquids Via a Unique Mechanism Involving Competitive Host-Guest Interactions," Dalton Transactions, 45 (2016) 19299-19310 C.-L. Hu, J. Xiong, L.-X. Gao, J. Li, H. Q. Zeng, Y. Zou and J.-F. Hu, "Diterpenoids from the Shed Trunk Barks of the Endangered Plant Pinus Dabeshanensis and their PTP1B Inhibitory Effects," RSC Advances, 6 (2016) 60467-60478 N. Hong, M. Li, Y. Yuan, T. Wang, M. Yi, H. Xu, H. Q. Zeng, J. Song and Y. Hong, "Dnd is a Critical Specifier of Primordial Germ Cells in the Medaka Fish," Stem Cell Reports, 6 (2016) 411-421 Y. P. Huo, C. Q. Pan, S. Y. Wang, S. M. Ji, T. F. Kong, L. Gao, N. Cai and H. Q. Zeng, "Color-Tunable Solid-State Emissions of Zn(II) and Cd (II) Complexes Derived from Cyano-Modified 2-Substituted 8-Hydroxyquinolines," Polyhedron, 119 (2016) 175-183 Y. Liu, J. Shen, C. Sun, C. L. Ren and H. Q. Zeng, "Intramolecularly Hydrogen-Bonded Aromatic Pentamers as Modularly Tunable Macrocyclic Receptors for Selective Recognition of Metal Ions," Journal of the American Chemical Society, 137 (2015) 12055-12063 X. Li, B. Li, L. Chen, J. Hu, C. Wen, Q. Zheng, L. Wu, H. Q. Zeng, B. Gong and L. Yuan, "Liquid-Crystalline Mesogens Based on Cyclo[6]aramides: Distinctive Phase Transitions in Response to Macrocyclic Host-Guest Interactions," Angewandte Chemie International Edition, 54 (2015) 11147-11152 C. Ren, J. Shen and H. Zeng, "One-Pot Synthesis of Strained Macrocyclic Pyridone Hexamers and their High Selectivity toward Cu2+ Recognition," Organic Letters, 17 (2015) 5946-5949 J. Xiong, Z.-L. Hong, L.-X. Gao, J. Shen, S.-T. Liu, G.-X. Yang, J. Li, H. Q. Zeng and J.-F. Hu, "Chlorabietols A-C, Phloroglucinol-Diterpene Adducts from the Chloranthaceae Plant Chloranthus oldhamii," The Journal of Organic Chemistry, 80 (2015) 11080-11085 S. P. Teong, G. Yi, H. Q. Zeng and Y. Zhang, "The Effects of Emulsion on Sugar Dehydration to 5-Hydroxymethylfurfural in a Biphasic System," Green Chemistry, 17 (2015) 3751-3755 W. L. Ma, C. Q. Wang, J. T. Li, K. Zhang, Y.-J. Lu, Y. P. Huo and H. Q. Zeng, "The Dynamics, Energetics and Selectivity of Water Chain-Containing Aquapores Created by the Self-Assembly of Aquafoldamer Molecules," Organic & Biomolecular Chemistry, 13 (2015) 10613-10619