Leggett, Graham - University of Sheffield

个人简介

Prof. Leggett obtained a BSc in Chemistry from UMIST in 1987. His PhD from the same institution, obtained in 1990, was followed by consecutive appointments as Research Associate at Universities of Washington and Nottingham. In 1994 he was appointed as lecturer at the University of Nottingham 1994-98. He became a Lecturer at UMIST in 1998, where he was subsequently promoted to senior lecturer and reader. In 2002 he was appointed as Professor of nanoscale analytical chemistry at the University of Sheffield.

研究领域

Scanning probe microscopy (SPM) has revolutionised our ability to characterise the surface morphologies of complex and difficult materials. However, much more exciting and potentially more powerful are the capabilities that SPM techniques provide for the measurement of surface properties and for the manipulation of molecular structure. Our work focuses on the development of quantitative measurement tools for the investigation of molecular and polymeric surfaces (for example, the development of friction and chemical force microscopies for studying nanometre scale tribological phenomena). Besides offering tools for surface characterisation, scanning probe instruments provide powerful capabilities for the modification of surface molecular structure. We have developed a new technique, scanning near-field photolithography, in which a scanning near-field optical microscope is used to fabricate structures that may be as small as 9 nm, using photochemical reactions. Our goal is to integrate top-down (lithographic) methods with bottom-up (synthetic) techniques by exploiting the versatility of photochemical methods as tools for executing very specific molecular transformations, in combination with the exquisite spatial resolution accessible in the near field. A particular emphasis of our work is the development of methods for the fabrication of biological nanostructures for use in novel highly miniaturised, high sensitivity analytical systems.

近期论文

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Tsargorodska A, Cartron ML, Vasilev C, Kodali G, Mass OA, Baumberg JJ, Dutton PL, Hunter CN, Törmä P & Leggett GJ (2016) Strong Coupling of Localized Surface Plasmons to Excitons in Light-Harvesting Complexes.. Nano Letters. View this article in WRRO Galloway JM, Bird SM, Talbot JE, Shepley PM, Bradley RC, El-Zubir O, Allwood DA, Leggett GJ, Miles JJ, Staniland SS & Critchley K (2016) Nano- and micro-patterning biotemplated magnetic CoPt arrays. Nanoscale, 8(22), 11738-11747. View this article in WRRO Zhang ZJ, Moxey M, Alswieleh AM, Morse AJ, Lewis AL, Geoghegan M & Leggett GJ (2016) Effect of Salt on Phosphorylcholine-based Zwitterionic Polymer Brushes. Langmuir, 32(20), 5048-5048. View this article in WRRO Xia S, Cartron M, Morby J, Bryant DA, Hunter CN & Leggett GJ (2016) Fabrication of Nanometer and Micrometer Scale Protein Structures by Site-Specific Immobilization of Histidine-Tagged Proteins to Aminosiloxane Films with Photoremovable Protein-Resistant Protecting Groups. Langmuir. View this article in WRRO Kumar S, Cartron ML, Mullin N, Qian P, Leggett GJ, Hunter CN & Hobbs JK (2016) Direct Imaging of Protein Organization in an Intact Bacterial Organelle Using High-Resolution Atomic Force Microscopy. ACS Nano. View this article in WRRO Rawlings AE, Bird SM, El-Zubir O, Leggett G & Staniland SS (2015) A novel design strategy for nanoparticles on nanopatterns: interferometric lithographic patterning of Mms6 biotemplated magnetic nanoparticles. Journal of Materials Chemistry C. View this article in WRRO