Gilmour, Ryan - Westfälische Wilhelms-Universität Münster

个人简介

Curriculum Vitae 10/2018 - 10/2019 Managing director of the Institute for Organic Chemistry,WWU Münster, Germany since 11/2016 Chair of Organic Chemistry & CiM Professor of Chemical Biology Organisch-Chemisches Institut, WWU Münster, Germany. 10/2012 CiMIC Professor of Chemical Biology & Professor of Organic Chemistry Organisch-Chemisches Institut, WWU Münster, Germany. 2008 - 2012 Alfred Werner Assistant Professor of Synthetic Organic Chemistry,Swiss Federal Institute of Technology (ETH) Zurich, Switzerland. 2007 - 2008 Post-doctoral Research Fellow, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland,Research Advisor: Professor Dr Peter H. Seeberger. 2006 - 2007 Post-doctoral Research Fellow, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr,Germany, Research Advisor: Professor Dr Alois Fürstner. 2002 - 2006 Ph.D. in Organic Chemistry, University Chemical Laboratory and Clare College,University of Cambridge, UK, Research advisor: Professor Dr Andrew B. Holmes FRS. 1998 - 2002 M.Chem. (Hons) First Class, School of Chemistry, University of St Andrews, UK,Masters degree in "Chemistry with Advanced Chemistry". Awards and Honours 2023 Fellow of the European Academy of Sciences Associate Editor, Chemical Science (August 2023- ) 2023 WWU Münster Research Prize / Forschungspreis 2023-2027 Editorial Advisory Board Member, ChemistryEurope 2023-2027 Editorial Advisory Board Member, European Journal of Organic Chemistry 2022 Henriette Herz Scout of the Alexander von Humboldt Foundation 2021-2022 Global Fellow, University of St Andrews, UK SYNTHESIS Best Paper Award 2021 2021 Corresponding Fellow of the Royal Society of Edinburgh (CorrFRSE) 2021 German Chemical Society Fluorine Publication Prize / GDCh Publikationspreis Fluorchemie 2020-2021 Prof. David Ginsburg Lecturer, Schulich Faculty of Chemistry, Technion - Israel Institute of Technology. 2019-2021 Editorial Advisory Board Member, Chemical Science. 2019-2021 Visiting Professor, University of Strathclyde, UK 2019 Faculty Award for Excellence in Teaching "Goldener Brendel" 2019 Allergan Lectureship, University of California Irvine, USA 2019 ERC Consolidator Grant 2018 Elected to the Research Council (Forschungsbeirat) of the WWU Münster 2017-2022 Elected to the Kinetics & Reaction Mechanisms section of ProcessNet, DECHEMA 2016-2018 Visiting Professor, University of Strathclyde, UK 2015 Fellow of the Royal Society of Chemistry 2013 ERC Starter Grant 2011 Ruzicka Prize of the ETH Zürich 2011 JSP Fellowship, 46th Bürgenstock Conference 2009 Thieme Journal Award 2007 Alfred Werner Assistant Professorship 2006 Membership of the Royal Society of Chemistry 2002 Organon Prize for Biological Chemistry 2000 CIBA Scholarship for Organic Chemistry

研究领域

1. Organofluorine Chemistry: The design of novel fluorinated bioisosteres to expand chemical space. 2. Stereocontrolled Construction of Fluorinated Glycostructures for Biomedicine: Applications in Neurology, Non-invasive Bacterial Imaging, Clinical Virology and Drug Discovery 3. Controlling 2D Chemical Space / Stereocontrolled Construction of Complex Polyenes: E → Z Isomerisation of Alkenes Enabled by Selective Energy Transfer Catalysis

近期论文

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Light Enabled Deracemization of Cyclopropanes by Al Salen Photocatalysis C. Onneken, T. Morack, J. Soika, O. Sokolova, N. Niemeyer, C. Mück-Lichtenfeld, C. G. Daniliuc, J. Neugebauer and R. Gilmour, Nature 2023, 10.1038/s41586-023-06407-8. Integrating I(I)/I(III) Catalysis in Reaction Cascade Design Enables the Synthesis of gem-Difluorinated Tetralins from Cyclobutanols J. Häfliger, L. Ruyet, N. Stübke, C. G. Daniliuc and R. Gilmour, Nature Communications 2023, 14, 3207. Direct Observation of Triplet States in the Isomerization of Alkenylboronates by Energy Transfer Catalysis T. J. B. Zähringer, M. Wienhold, R. Gilmour and C. Kerzig, J. Am. Chem. Soc. 2023, accepted for publication. Forging Medium Rings via I(I)/I(III)-Catalyzed Diene Carbofunctionalization Y.-J. Yu, J. Häfliger, Z.-X. Wang, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2023, e202309789. Geometric Isomerisation of Bifunctional Vinyl Fluoride Linchpins: Stereodivergence in Amide and Polyene Bioisostere Synthesis M. Wienhold, B. Kweon, C. McLaughlin, M Schmitz, T. J. B. Zähringer, C. G. Daniliuc, C. Kerzig and R. Gilmour, Angew. Chem. Int. Ed. 2023, e202304150. Fluorinated Carbohydrates for 18F-Positron Emission Tomography (PET) E. Campbell, C. Jordan and R. Gilmour, Chem. Soc. Rev. 2023, 52, 3599-3626. Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes Y.-J. Yu, M. Schäfer, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2023, 62, e202214906. Fluorine-Directed Automated Mannoside Assembly C. Teschers and R. Gilmour, Angew. Chem. Int. Ed. 2023, 135 e202213304. DOI numbers 10.1002/anie.202213304 and 10.1002/ange.202213304. Fluorocyclisation of Oximes to Isoxazolines via I(I)/I(III) Catalysis J. Neufeld, C. G. Daniliuc and R. Gilmour, Helv. Chim. Acta 2023, e202200183. Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of cis-α,α-Difluorocyclopropanes K. Livingstone, K. Siebold, S. Meyer, V. Martín-Heras, C. G. Daniliuc, and R. Gilmour, ACS Catal. 2022, 12, 14507–14516. Organophotocatalytic N–O Bond Cleavage of Weinreb Amides: Mechanism-Guided Evolution of a PET to ConPET Platform J. Soika, C. McLaughlin, T. Neveselý, C. G. Daniliuc, J. J. Molloy and R. Gilmour, ACS Catal. 2022, 12, 10047-10056. Cyclopropene Activation via I(I)/I(III) Catalysis: Proof of Principle and Application in Direct Tetrafluorination S. Meyer, L. Göbel, K. Livingstone, C. Roblick, C. G. Daniliuc and R. Gilmour, Tetrahedron 2022, 132925. Stereocontrolled Synthesis of Fluorinated Isochromans via Iodine(I)/Iodine(III) Catalysis J. Häfliger, O. O. Sokolova, M. Lenz, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, e202205277. DOI:10.1002/anie.202205277 and 10.1002/ange.202205277. Regio- and Enantioselective Intermolecular Aminofluorination of Alkenes via Iodine(I)/Iodine(III) Catalysis M. Schäfer, T. Stünkel, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, e202205508. DOI numbers 10.1002/anie.202205508 and 10.1002/ange.202205508 Advances in the E → Z Isomerization of Alkenes using Small Molecule Photocatalysts T. Neveselý, M. Wienhold, J. J. Molloy and R. Gilmour, Chem. Rev. 2022, 122, 2650-2694. Leveraging the n→π* Interaction in Alkene Isomerisation by Selective Energy Transfer Catalysis T. Neveselý, J. J. Molloy, C. McLaughlin, L. Brüss, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, 61, e202113600. Leveraging fluorine (stereoelectronic) effects in catalysis in The Chemistry of Organofluorine Compounds J. Neufeld, K. Livingstone and R. Gilmour, in The Chemistry of Organofluorine Compounds, Patai´s Chemistry of Functional Groups (2022) (Eds. I. Marek, V. Gouverneur, M. Gandelman), Wiley-VCH Verlag GmbH & Co, Weinheim. Enantiodivergent Prenylation via Deconjugative Isomerization T. Morack, C. Onneken, H. Nakakohara, C. Mück-Lichtenfeld and R. Gilmour, ACS Catal. 2021, 11, 11929–11937. Illuminating Anti-Hydrozirconation: Controlled Geometric Isomerization of an Organometallic Species T. Hostmann, T. Nevesely and R. Gilmour, Chem. Sci. 2021, 12, 10643 - 10648. Expanding Organofluorine Chemical Space: The Design of Chiral Fluorinated Isosteres Enabled by I(I)/I(III) Catalysis S. Meyer, J. Häfliger and R. Gilmour, Chem. Sci. 2021, 12, 10686 - 10695 An I(I)/I(III) Catalysis Route to the Heptafluoroisopropyl Group: A Privileged Module in Contemporary Agrochemistry V. Martín-Heras, C. G. Daniliuc and R. Gilmour, Synthesis 2021, 53, 4203-4212. Emerging Fluorinated Motifs: Synthesis, Properties, and Applications J. Neufeld and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 20592-20593. Difluorination of α-(bromomethyl)styrenes via I(I)/I(III) catalysis: facile access to electrophilic linchpins for drug discovery J. Häfliger, K. Livingstone, C. G. Daniliuc and R. Gilmour, Chem. Sci. 2021, 12, 6148–6152. Trifluorinated Tetralins via I(I)/I(III)-Catalysed Ring Expansion: Programming Conformation by [CH2CH2] → [CF2CHF] Isosterism J. Neufeld, T. Stünkel, C. Mück-Lichtenfeld, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 13647-13651. Oligodendroglial Glycolipids in (Re) Myelination: Implications for Multiple Sclerosis Research L. Nowack, C. S. Teschers, S. Albrecht, R. Gilmour, Nat. Prod. Rep. 2021, 38, 890-904. A Chiral, Pentafluorinated Isopropyl Group via Iodine(I)/(III) Catalysis S. Meyer, J. Häfliger, M. Schäfer, J. J. Molloy, C. G. Daniliuc, and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 6430-6434. Coumarins by Direct Annulation: β-Borylacrylates as Ambiphilic C3-Synthons M. Wienhold, J. J. Molloy, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 685-689. Enhancing Glycan Stability via Site-Selective Fluorination: Modulating Substrate Orientation by Molecular Design A. Axer, R. P. Jumde, S. Adam, A. Faust, M. Schäfers, M. Fobker, J. Koehnke, A. K. H. Hirsch and R. Gilmour, Chem. Sci. 2021, 12, 1286-1294.