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个人简介

My primary research area is glial cell biology in health and disease. Three outstanding events determined my research career. First, my PhD with Joan Abbott (King’s College London) introduced me to glial cells. Then, I was first introduced to the optic nerve model in my postdoc with Bruce Ransom at Yale University, USA. Finally, in my first tenured position at Guy’s and St Thomas’, I met Martin Berry, who stimulated my interest in neurodegeneration. I was awarded a personal Chair at King’s College London in 2002 and moved to Portsmouth in 2006, where I hold a personal Chair. I have been invited to write and speak on glial cell biology on numerous occasions, and I have written 2 books on glial cell biology, with my close friend and colleague Alex Verkhratsky (Manchester). For more information about my research please visit my lab page

研究领域

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My group uses multiple cell biological, genetic, molecular, anatomical and physiological techniques to study glial cell biology in health and diseases such as Multiple Sclerosis, glaucoma, epilepsy, ischemia, cerebral palsy, stroke and degeneration (reviewed in Butt et al. 2004; Bolton & Butt, 2005). A major interest of my group is the regulation of glial cell fate and the mechanisms controlling myelination, and I have recently become interested in glial cells of the enteric nervous system, which benefit from collaboration with members of IBBS, together with a number of national and international groups (see below).

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