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An-Di Guo,# Ke-Nian Yan,# Hao Hu,# Linhui Zhai, Teng-fei Hu, Haixia Su, Yijia Chi, Jinyin Zha, Yechun Xu, Dongxin Zhao, Xiaojie Lu, Yong-Jiang Xu, Jian Zhang, Minjia Tan,* Xiao-Hua Chen*. Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors. Nat. Chem., 2023，in press，DOI : 10.1038/s41557-023-01196-z（# contributed equally）
An-Di Guo, Xiao-Hua Chen*. Genetically Encoded Noncanonical Amino Acids in Proteins to Investigate Lysine Benzoylation. Methods Mol. Biol., 2023, 2676, in press, https://doi.org/10.1007/978-1-0716-3251-2_9.
Yan Xu, Dingqiang Fu, Yi Yuan, Yan Peng, Juan Dong, Feng Du, Xin Huang, Guangxun Li, Xiaohua Chen,* Qiwei Wang,* and Zhuo Tang*; A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function，Cell Reports Physical Science, 2022, 3, 101064.
Dan Wei,+ Hanlin Wang,+ Qinghe Zeng,+ Wenjing Wang, Bingbing Hao, Xule Feng, Peipei Wang, Ning Song, Weijuan Kan, Guifang Huang, Xiaoyu Zhou, Minjia Tan, Yubo Zhou, Ruimin Huang,* Jia Li,* Xiao-Hua Chen*. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer; J. Med. Chem., 2021, 64, 14822-14847 ( +, contributed equally )
Hongtao Tian, jiale yang, An-Di Guo, Yu Ran, Yun-Zhi Yang, Bing Yang,Ruimin Huang, Haiming Liu*, Xiao-Hua Chen*. Genetically Encoded Benzoyllysines Serve as Versatile Probe for Interrogating Histone Benzoylations and Interactions in Living Cells; ACS Chem. Biol., 2021,16, 2560-2569.
An-Di Guo, Ke-Huan Wu, Xiao-Hua Chen*. Light-induced efficient and residue-selective bioconjugation of native proteins via indazolone formation; RSC Advances, 2021, 11, 2235.
An-Di Guo,+ Dan Wei,+ Hui-Jun Nie,+ Hao Hu, Chengyuan Peng, Shao-Tong Li, Ke-Nian Yan, Bin-Shan Zhou, Lei Feng, Chao Fang, Minjia Tan, Ruimin Huang, Xiao-Hua Chen*. Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation; Nat. Commun., 2020, 11, 5472; (+, contributed equally ).
Wei Hu, Yi Yuan, Cai-Hu Wang, Hong-Tao Tian, An-Di Guo, Hui-Jun Nie, Hao Hu, Minjia Tan, Zhuo Tang,* Xiao-Hua Chen*. Genetically Encoded Residue-Selective Photo-Crosslinker to Capture Protein-Protein Interactions in Living Cells; Chem., 2019, 5, 2955-2968.
Hui-Jun Nie, An-Di Guo, Hai-Xia Lin, Xiao-Hua Chen*. Rapid and halide compatible synthesis of 2-Nsubstituted indazolone derivatives via photochemical cyclization in aqueous media, RSC Adv., 2019, 9, 13249-13253.
Nan Li,* Honglian Feng, Qian Gong, Chunxiao Wu, Hao Zhou, Zhiyan Huang, Jun Yang, Xiao-Hua Chen,* Na Zhao.* BINOL-based chiral aggregation-induced emission luminogens and t.heir application in detecting copper(II) ions in aqueous media. J. Mater. Chem.C, 2015, 3, 11458-11463.
Xiao-Hua Chen, Zheng Xiang, Ying S. Hu, Vanessa K. Lacey, Hu Cang, and Lei Wang*. Genetically Encoding an Electrophilic Amino Acid for Protein Stapling and Covalent Binding to Native Receptors. ACS Chem. Biol., 2014, 9, 1956-1961.
Xiao-Hua Chen, Alexander Roloff, Oliver Seitz*. Consecutive Signal Amplification for DNA Detection Based on De Novo Fluorophore Synthesis and Host-Guest Chemistry. Angew. Chem. Int. Ed., 2012, 51, 4479-4483.
Xiao-Hua Chen, Jie Yu and Liu-Zhu Gong*. The Role of Double Hydrogen Bonds in Asymmetric Direct Aldol Reactions Catalyzed by Amino Amide Derivatives. Chem. Commun., 2010, 46, 6437-6448.
Xiao-Hua Chen, Qiang Wei, Shi-Wei Luo, Han Xiao, and Liu-Zhu Gong*. Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity. J. Am. Chem. Soc.; 2009, 131, 13819-13825
Xiao-Hua Chen, Wen-Quan Zhang, and Liu-Zhu Gong*. Asymmetric Organocatalytic Three-Component 1,3-Dipolar Cycloaddition: Control of Stereochemistry via a Chiral Bronsted Acid Activated Dipole. J. Am. Chem. Soc.; 2008, 130, 5652-5653.
Xiao-Hua Chen, Xiao-Ying Xu, Hua Liu, Lin-Feng Cun, and Liu-Zhu Gong*. Highly Enantioselective Organocatalytic Biginelli Reaction. J. Am. Chem. Soc.; 2006, 128, 14802-14803.
Xiao-Hua Chen, Shi-Wei Luo, Zhuo Tang, Lin-Feng Cun, Ai-Qiao Mi, Yao-Zhong Jiang, and Liu-Zhu Gong*. Organocatalyzed Highly Enantioselective Direct Aldol Reactions of Aldehydes with Hydroxyacetone and Fluoroacetone in Aqueous Media. The Use of Water to Control the Regioselectivity. Chem. Eur. J.; 2007. 13. 689-701.
Liu-Zhu Gong,* Xiao-Hua Chen, and Xiao-Ying Xu. Asymmetric Organocatalytic Biginelli Reactions: a New Approach to Quickly Access Optically Active 3, 4-Dihydropyrimidin-2-(1H)-ones. Chem. Eur. J.; 2007, 13. 8920-8926.
Long He, Xiao-Hua Chen, De-Nan Wang, Shi-Wei Luo*, Wen-Quan Zhang, Jie Yu, Lei Ren, and Liu-Zhu Gong*. Binaphthol-derived Bisphosphoric Acids Serve as Efficient Organocatalysts for Highly Enantioselective 1, 3-Dipolar Cycloaddition of Azomethine Ylides to Electron-Deficient Olefins. J. Am. Chem. Soc.; 2011, 133, 13504-13518.
Nan Li, Xiao-Hua Chen, Shi-Ming Zhou, Shi-Wei Luo, Jin Song, Lei Ren, and Liu-Zhu Gong*. Asymmetric Amplification in Phosphoric Acid Catalyzed Reactions. Angew. Chem. Int. Ed., 2010, 49, 6378-6381.
Nan Li, Xiao-Hua Chen, Jin Song, Shi-Wei Luo, Wu Fan, and Liu-Zhu Gong*. Highly Enantioselective Organocatalytic Biginelli and Biginelli-Like Condensations: Reversal of the Stereochemistry by Tuning the 3, 3′-Disubstituents of Phosphoric Acids. J. Am. Chem. Soc.; 2009, 131, 15301-15310.
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