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个人简介

2015 - date Reader in Inflammatory Cell Biology, Aston University 2012 - date Senior Lecturer in Cell Biology, Aston University 2005-2012 Lecturer in Cell Biology, Aston University 2001-2005 Senior Research Fellow MRC Centre for Inflammation Research The University of Edinburgh, UK 1997-2001 Research Fellow School of Biomedical Sciences, Nottingham University, UK 1995-1997 Research Fellow Department of Immunology The University of Birmingham, UK 1995 Ph.D. MicrobiologySchool of Biological Sciences The University of Birmingham, UK (Wellcome Prize studentship) 1991 B.Sc. (HONS) First Class, Microbiology Department of Cell & Structural Biology, The University of Manchester

研究领域

Apoptotic cell-derived extracellular vesicles (ACdEV) – structure/function relationships Molecular mechanisms underlying recognition and clearance of apoptotic cell and pathogens Monocyte and macrophage biology and innate immunity Monocytes and macrophages in ageing and cardiovascular disease Apoptosis & Identification of apoptotic cells

近期论文

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Nguyen, DB, Thuy Ly, TB, Wesseling, MC, Hittinger, M, Torge, A, Devitt, A, Perrie, Y & Bernhardt, I 2016, 'Characterization of microvesicles released from human red blood cells' Cellular Physiology and Biochemistry, vol. 38, no. 3, pp. 1085-1099,10.1159/000443059 Perrie, Y, Crofts, F, Devitt, A, Griffiths, HR, Kastner, E & Nadella, V 2016, 'Designing liposomal adjuvants for the next generation of vaccines' Advanced Drug Delivery Reviews, vol. 99, no. Part A, pp. 85-96,10.1016/j.addr.2015.11.005 Pararasa, C, Ikwuobe, J, Shigdar, S, Boukouvalas, A, Nabney, IT, Brown, JE, Devitt, A, Bailey, CJ, Bennett, SJ & Griffiths, HR 2016, 'Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPAR?' Aging Cell, vol. 15, no. 1, pp. 128-139,10.1111/acel.12416 Pararasa, C, Ikwuobe, J, Shigdar, S, Boukouvalas, A, Nabney, IT, Brown, JE, Devitt, A, Bailey, CJ, Bennett, SJ & Griffiths, HR 2016, 'Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPAR?' Aging Cell, vol. 15, no. 1, pp. 128-139,10.1111/acel.12416 Nadella, V, Wang, Z, Johnson, TS, Griffin, M & Devitt, A 2015, 'Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells' BBA - Molecular Cell Research, vol. 1853, no. 1, pp. 201-212,10.1016/j.bbamcr.2014.09.020 Marshall, LJ, Oguejiofor, W, Willetts, RS, Griffiths, HR & Devitt, A 2015, 'Developing accurate models of the human airways' Journal of Pharmacy and Pharmacology, vol. 67, no. 3, pp. 464-472,10.1111/jphp.12340 Chimonides, GF, Behrendt, JM, Chundoo, E, Bland, C, Hine, AV, Devitt, A, Nagel, DA & Sutherland, AJ 2014, 'Cellular uptake of ribonuclease A-functionalised core-shell silica microspheres' Journal of Materials Chemistry B, vol. 2, no. 42, pp. 7307-7315,10.1039/C4TB01130A Kilari, RS, Perry, CJ, Devitt, A, Safrany, ST & Nicholl, ID 2014, 'Aspirin and aspirin analogs on esophageal cancer' Cancer Research, vol. 74, no. 19 Supplement, Abstract 2527,10.1158/1538-7445.AM2014-2527 Nagel, D, Behrendt, JM, Chimonides, GF, Torr, EE, Devitt, A, Sutherland, AJ & Hine, AV 2014, 'Polymeric microspheres as protein transduction reagents' Molecular and Cellular Proteomics, vol. 13, no. 6, pp. 1543-1551,10.1074/mcp.O113.034900 Griffiths, HR, Dias, I, Willetts, RS & Devitt, A 2014, 'Redox regulation of protein damage in plasma' Redox biology, vol. 2, no. 1, pp. 430-435,10.1016/j.redox.2014.01.010 Kaur, R, Henriksen-Lacey, M, Wilkhu, J , Devitt, A , Christensen, D & Perrie, Y 2014, ' Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on Bilayer properties, biodistribution, and immune responses ' Molecular pharmaceutics , vol 11, no. 1, pp. 197-207., 10.1021/mp400372j Kaur, R, Henriksen-Lacey, M, Wilkhu, J, Devitt, A, Christensen, D & Perrie, Y 2014, 'Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on Bilayer properties, biodistribution, and immune responses' Molecular Pharmaceutics, vol. 11, no. 1, pp. 197-207,10.1021/mp400372j Hawkins, L, Alghareeb, K, Nadella, V, Chauhan, P, Bland, CE & Devitt, A 2014, 'Physical and functional characterisation of apoptotic cell-derived extracellular vesicles' British Society for Immunology (BSI) annual congress, Brighton, United Kingdom,1/12/14 -4/12/14 , . Alghareeb, K, Nadella, V, Bland, CE & Devitt, A 2014, 'Characterisation of ICAM-3 and extracellular vesicles in the clearance of apoptotic cells' British Society for Immunology (BSI) annual congress, Brighton, United Kingdom,1/12/14 -4/12/14 , . Hawkins, LA & Devitt, A 2013, 'Current understanding of the mechanisms for clearance of apoptotic cells-a fine balance' Journal of Cell Death, vol. 6, no. 3932, pp. 57-68,10.4137/JCD.S11037 Ghattas, A, Griffiths, HR, Devitt, A, Lip, GYH & Shantsila, E 2013, 'Monocytes in coronary artery disease and atherosclerosis: where are we now?' Journal of the American College of Cardiology, vol. 62, no. 17, pp. 1541-1551,10.1016/j.jacc.2013.07.043 Thomas, L, Bielemeier, A, Lambert, PA, Darveau, RP, Marshall, LJ & Devitt, A 2013, 'The N-terminus of CD14 acts to bind apoptotic cells and confers rapid-tethering capabilities on non-myeloid cells: CD14 and rapid tethering of apoptotic cells' PLoS ONE, vol. 8, no. 7, e0070691,10.1371/journal.pone.0070691 Tennant, I, Pound, JD, Marr, LA, Willems, JJLP, Petrova, S, Ford, CA, Paterson, M, Devitt, A & Gregory, CD 2013, 'Innate recognition of apoptotic cells: novel apoptotic cell-associated molecular patterns revealed by crossreactivity of anti-LPS antibodies' Cell Death and Differentiation, vol. 20, no. 5, pp. 698-708,10.1038/cdd.2012.165 Ghattas, A, Shantsila, E, Devitt, A, Griffiths, H & Lip, GYL 2013, 'Monocyte subpopulation counts and TNF alpha associations with clinical outcome post ST elevation myocardial infarction' Heart, vol. 99, no. Suppl.2, 243, pp. A129-A130,10.1136/heartjnl-2013-304019.243 Hill, E, Nagel, D, O' Neil, J, Torr, L, Woehrling, E, Devitt, A & Coleman, M 2013, 'Effects of lithium and valproic acid on gene expression and phenotypic markers in an NT2 neurosphere model of neural development' PLoS ONE, vol. 8, no. 3, e58822,10.1371/journal.pone.0058822

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