Bailey, Cliff - Aston University - School of Life & Health Sciences, Pharmacy

个人简介

Professor and Head of Diabetes Research, Aston University Formerly Reader and Senior Lecturer in Pharmacology, and Lecturer in Physiology, Aston University 1998 FRCP, Fellowship, Royal College of Physicians, Edinburgh 1996 FRCPath, Fellowship, Royal College of Pathologists

研究领域

Diabetes Research at Aston University studies the regulation of nutrient metabolism, the pathogenesis of diabetes mellitus and obesity, and the development of new therapies. Specific interests include: Pathogenesis and interventional approaches against insulin resistance Discovery and development of agents to treat diabetes and obesity Islet transplantation and therapeutic use of genetically modified insulin-releasing cells Study design and evaluation of therapies for diabetes and obesity

近期论文

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Wilding, J, Bailey, C, Rigney, U, Blak, B, Beekman, W & Emmas, C 2016, 'Glycated hemoglobin, body weight and blood pressure in type 2 diabetes patients initiating dapagliflozin treatment in primary care: a retrospective study' Diabetes Therapy, vol. In press,10.1007/s13300-016-0193-8 Tahrani, AA, Barnett, AH & Bailey, CJ 2016, 'Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus' Nature Reviews Endocrinology, vol. Advance online publication,10.1038/nrendo.2016.86 McCreight, LJ, Bailey, CJ & Pearson, ER 2016, 'Metformin and the gastrointestinal tract' Diabetologia, vol. 59, no. 3, pp. 426-435,10.1007/s00125-015-3844-9 Pararasa, C, Ikwuobe, J, Shigdar, S, Boukouvalas, A, Nabney, IT, Brown, JE, Devitt, A, Bailey, CJ, Bennett, SJ & Griffiths, HR 2016, 'Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPAR?' Aging Cell, vol. 15, no. 1, pp. 128-139,10.1111/acel.12416 Pararasa, C, Ikwuobe, J, Shigdar, S, Boukouvalas, A, Nabney, IT, Brown, JE, Devitt, A, Bailey, CJ, Bennett, SJ & Griffiths, HR 2016, 'Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPAR?' Aging Cell, vol. 15, no. 1, pp. 128-139,10.1111/acel.12416 Bailey, CJ, Tahrani, AA & Barnett, AH 2016, 'Future glucose-lowering drugs for type 2 diabetes' The Lancet Diabetes and Endocrinology, vol. In press,10.1016/S2213-8587(15)00462-3 Bailey, CJ 2015, 'The current drug treatment landscape for diabetes and perspectives for the future' Clinical pharmacology and therapeutics, vol. 98, no. 2, pp. 170–184,10.1002/cpt.144 Bailey, CJ 2015, 'Safety of antidiabetes medications: an update' Clinical pharmacology and therapeutics, vol. 98, no. 2, pp. 185–195,10.1002/cpt.125 Bailey, CJ, Morales Villegas, EC, Woo, V, Tang , W, Ptaszynska, A & List, JF 2015, 'Efficacy and safety of dapagliflozin monotherapy in people with Type 2 diabetes: a randomized double-blind placebo-controlled 102-week trial' Diabetic Medicine, vol. 32, no. 4, pp. 531-541,10.1111/dme.12624 Pararasa, C, Bailey, CJ & Griffiths, HR 2015, 'Ageing, adipose tissue, fatty acids and inflammation' Biogerontology, vol. 16, no. 2, pp. 235-248,10.1007/s10522-014-9536-x Qureshi, KM, Lee, J, Paget, MB, Bailey, CJ, Curnow, SJ, Murray, HE & Downing, R 2015, 'Low gravity rotational culture and the integration of immunomodulatory stem cells reduce human islet allo-reactivity' Clinical Transplantation, vol. 29, no. 1, pp. 90-98,10.1111/ctr.12488 Day, C & Bailey, CJ 2015, 'Pharmacotherapies to manage diabesity: an update' Diabesity in practice, vol. 4, no. 1, pp. 14-23. Inzucchi, SE, Lipska, KJ, Mayo, H, Bailey, CJ & McGuire, DK 2014, 'Metformin in patients with type 2 diabetes and kidney disease: a systematic review' JAMA: Journal of the American Medical Association, vol. 312, no. 24, pp. 2668-2675,10.1001/jama.2014.15298 Home, P, Riddle, M, Cefalu, WT, Bailey, CJ, Bretzel, RG, del Prato, S, Leroith, D, Schernthaner, G, van Gaal, L & Raz, I 2014, 'Response to comment on Home et al. Insulin therapy in people with type 2 diabetes: opportunities and challenges? Diabetes care 2014;37:1499-1508' Diabetes Care, vol. 37, no. 11, e247,10.2337/dc14-1790 Pararasa, C, Bailey, C & Griffiths, H 2014, 'Macrophage polarisation by fatty acids is PPARgamma-dependent' Free Radical Biology and Medicine, vol. 75, no. Suppl.1, P32, pp. S31-S32,10.1016/j.freeradbiomed.2014.10.764 Ahrén, B, Gautier, J-F, Berria, R, Stager, W, Aronson, R & Bailey, CJ 2014, 'Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials' Diabetes, Obesity and Metabolism, vol. 16, no. 9, pp. 861-868,10.1111/dom.12290 Bailey, CJ, Azar, ST, Blonde, L, Dicker, D, Puig-domingo, M, Eliaschewitz, FG, Nikonova, E, Roussel, R, Sakaguchi, K, Sauque-Reyna, L & Nauck, M 2014, 'Relationship between changes in postprandial glucagon, patient characteristics, and response to lixisenatide as add-on to oral antidiabetics' Diabetologia, vol. 57, no. Suppl.1, 846, pp. S344,10.1007/s00125-014-3355-0 Bailey, CJ 2014, 'Metformin' . in GE Umpierrez (ed.),Therapy for diabetes mellitus and related disorders.6th edn, American Diabetes Association, Alexandria, VA (US), pp. 341-358,10.2337/9781580405096 Bailey, CJ 2014, ' Treatment with metformin '. in The Metabolic Syndrome: Pharmacology and Clinical Aspects. vol. 9783709113318, Springer-Verlag Wien, pp. 99-116., 10.1007/978-3-7091-1331-8_8 Fouqueray, P, Pirags, V, Diamant, M, Schernthaner, G, Lebovitz, HE, Inzucchi, SE & Bailey, CJ 2014, 'The efficacy and safety of imeglimin as add-on therapy in patients with type 2 diabetes inadequately controlled with sitagliptin monotherapy' Diabetes Care, vol. 37, no. 7, pp. 1924-1930,10.2337/dc13-2349