Griffiths, Gareth - Aston University - School of Engineering & Applied Science

个人简介

I obtained my PhD from the University of Bristol working on the biosynthesis of polyunsaturated fatty acids and triacylglycerol assembly and this was followed by a number of postdoctoral positions in leading lipid laboratories in Uppsala (Sweden), Cardiff and Bristol. I was appointed Research Leader at Horticulture Research International (1994) and led a team investigating lipid metabolism in plants and was promoted to Senior Research Leader in 2002. In 2005, I joined Aston University as a Lecturer in Chemistry teaching biological chemistry across the undergraduate curriculum and developed research on lipid oxidation. Over the past six years my research has focused on the oxidative behaviour of high value plant oils and ‘green’ agrochemicals based on plant oxylipins structures (molecular mimicking). In 2011, I moved my research to the European Bioenergy Research Institute (EBRI) at Aston University where I lead the Algal Research Laboratory. Current research is focused on oxylipin and polyamine metabolism and their influence on biomass production using the green unicellular microalga, Chlamydomonas, as a model system. My biochemical expertise combined with thermochemical processing expertise within EBRI has led to a number of recent advances in the area of product formation from intermediate pyrolysis.

近期论文

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Griffiths, G 2015, 'Biosynthesis and analysis of plant oxylipins' Free Radical Research, vol. 49, no. 5, pp. 565-582,10.3109/10715762.2014.1000318 Patel, T, Blyth, JC, Griffiths, G, Kelly, D & Talcott, JB 2014, 'Moderate relationships between NAA and cognitive ability in healthy adults: implications for cognitive spectroscopy' Frontiers in Human Neuroscience, vol. 8, 39,10.3389/fnhum.2014.00039 Kebelmann, K, Hornung, A, Karsten, U & Griffiths, G 2013, 'Thermo-chemical behaviour and chemical product formation from Polar seaweeds during intermediate pyrolysis' Journal of Analytical and Applied Pyrolysis, vol. 104, pp. 131-138,10.1016/j.jaap.2013.08.012 Kebelmann, K, Hornung, A, Karsten, U & Griffiths, G 2013, 'Intermediate pyrolysis and product identification by TGA and Py-GC/MS of green microalgae and their extracted protein and lipid components' Biomass and Bioenergy, vol. 49, pp. 38-48,10.1016/j.biombioe.2012.12.006 Zhou, Y, Behrendt, J, Sutherland, AJ & Griffiths, G 2011, 'Synthetic molecular mimics of naturally occurring cyclopentenones exhibit antifungal activity towards pathogenic fungi' Microbiology, vol. 157, no. 12, pp. 3435-3445,10.1099/mic.0.052233-0 Campbell, D, Griffiths, G & Tighe, BJ 2011, 'Tear analysis and lens-tear interactions: part II. Ocular lipids-nature and fate of meibomian gland phospholipids' Cornea, vol. 30, no. 3, pp. 325-332,10.1097/ICO.0b013e3181eae239 Prost, I, Dhondt, S, Rothe, G, Vicente, J, Rodriguez, MJ, Kift, N, Carbonne, F, Griffiths, G, Esquerré-Tugayé, M-T, Rosahl, S, Castresana, C, Hamberg, M & Fournier, J 2005, 'Evaluation of the antimicrobial activities of plant oxylipins supports their involvement in defense against pathogens' Plant Physiology, vol. 139, no. 4, pp. 1902-1913,10.1104/pp.105.066274 Wagstaff, C, Malcolm, P, Rafiq, A, Leverentz, M, Griffiths, G, Thomas, B, Stead, A & Rogers, H 2003, 'Programmed cell death (PCD) processes begin extremely early inAlstroemeriapetal senescence' New Phytologist, vol. 160, no. 1, pp. 49-59,10.1046/j.1469-8137.2003.00853.x Chanasut, U, Rogers, HJ, Leverentz, MK, Griffiths, G, Thomas, B, Wagstaff, C & Stead, AD 2003, 'Increasing flower longevity inAlstroemeria' Postharvest Biology and Technology, vol. 29, no. 3, pp. 325-333,10.1016/S0925-5214(03)00048-6 Griffiths, G, Trueman, L, Crowther, T, Thomas, B & Smith, B 2002, 'Onions: a global benefit to health' Phytotherapy Research, vol. 16, no. 7, pp. 603-615,10.1002/ptr.1222 Leverentz, MK, Wagstaff, C, Rogers, HJ, Stead, AD, Chanasut, U, Silkowski, H, Thomas, B, Weichert, H, Feussner, I & Griffiths, G 2002, 'Characterization of a novel lipoxygenase-independent senescence mechanism inAlstroemeria peruvianafloral tissue' Plant Physiology, vol. 130, no. 1, pp. 273-283,10.1104/pp.000919 Wagstaff, C, Leverentz, MK, Griffiths, G, Thomas, B, Chanasut, U, Stead, AD & Rogers, HJ 2002, 'Cysteine protease gene expression and proteolytic activity during senescence ofAlstroemeriapetals' Journal of Experimental Botany, vol. 53, no. 367, pp. 233-240,10.1093/jexbot/53.367.233 Page, T, Griffiths, G & Buchanan-Wollaston, V 2001, 'Molecular and biochemical characterization of postharvest senescence in broccoli' Plant Physiology, vol. 125, no. 2, pp. 718-727,10.1104/pp.125.2.718