Urban, Sylvia - RMIT University - School of Science, Applied Sciences

研究领域

The research speciality of Dr Urban is aligned with the research field of natural products chemistry, involving skills in the areas of chromatography for purification and instrumental analysis and interpretation for structural characterisation and elucidation. Dr Urban is the research leader and founder of the Marine and Terrestrial Natural Product (MATNAP) research group in the School of Applied Sciences (Discipline of Applied Chemistry). The research scope of the group is to explore the biodiversity of Australian marine and terrestrial organisms (eg. Plants, fungi, sponges, algae etc…) in the quest for new compounds for the purposes of drug discovery other applications. To expedite the process of discovery, various dereplication and chemical profiling strategies have become an important focus of the research. . Major research interests Natural product chemistry isolation and structural elucidation NMR spectroscopy and mass spectrometry for characterisation of natural products High Performance/Pressure Liquid Chromatography (HPLC) and other chromatographic techniques for natural product purification (analysis of complex samples and extraction methodologies for natural products) Hyphenated spectroscopic techniques such as HPLC-NMR and HPLC-MS for natural product profiling Analytical/Organic chemistry and instrumental analysis for structural characterisation Biological evaluation of natural products (drug discovery and other applications)

近期论文

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Wimalasiri, D.,Piva, T.,Urban, S.,Huynh, T. (2016). Morphological and genetic diversity of Momordica cochinchinenesis (Cucurbitaceae) in Vietnam and Thailand In: Genetic Resources and Crop Evolution: an international journal, 63, 19 - 33 Consolacion, R.,Tan, M.,Ting, J.,Reyes, R.,Brkljaca, R.,Urban, S. (2016). Chemical constituents of Pleurotus djamor In: Der Pharma Chemica, 8, 343 - 346 Urban, S.,Brkljaca, R.,Hoshino, M.,Lee, S.,Fujita, M. (2016). Determination of the absolute configuration of the pseudo-symmetric natural product elatenyne by the crystalline sponge method In: Angewandte Chemie, 55, 2678 - 2682 Fong, S.,Piva, T.,Dekiwadia, C.,Urban, S.,Huynh, T. (2016). Comparison of cytotoxicity between extracts of Clinacanthus nutans (Burm. F.) Lindau leaves from different locations and the induction of apoptosis by the crude methanol leaf extract in D24 human melanoma cells In: BMC Complementary and Alternative Medicine, 16, 1 - 12 Consolacion, R.,Ebajo Jr, V.,Reyes, R.,Brkljaca, R.,Urban, S. (2015). Sterols and lipids from Pleurotus florida In: Der Pharma Chemica, 7, 331 - 336 Consolacion, R.,Ebajo Jr, V.,Tan, M.,Brkljaca, R.,Urban, S. (2015). Chemical constituents from Raphanus sativus In: Der Pharma Chemica: Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry, 7, 354 - 357 Ebajo Jr, V.,Aurigue, F.,Brkljaca, R.,Urban, S.,Ragusa, C. (2015). Chemical constituents of Hoya wayetii Kloppenb. In: International Journal of Pharmacognosy and Phytochemical Research, 7, 1042 - 1045 Ebajo Jr, V.,Brkljaca, R.,Urban, S.,Ragusa, C. (2015). Chemical Constituents of Hoya buotii Kloppenb. In: Journal of Applied Pharmaceutical Science, 5, 69 - 72 Ragusa, C.,Ebajo Jr, V.,De Los Reyes, M.,Mandia, E.,Brkljaca, R.,Urban, S. (2015). Triterpenes and sterols from sonneratia alba In: International Journal of Current Pharmaceutical Review and Research, 6, 256 - 261 Consolacion, R.,Ebajo Jr, V.,Tan, M.,Oyong, G.,Brkljaca, R.,Urban, S. (2015). Lipids and sterol from Berberis vulgaris L. var. asperma In: Der Pharmacia Lettre, 7, 183 - 186