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1992年-1996年,清华大学工程力学系,本科 1996年-1999年,清华大学工程力学系,硕士 1999年-2003年,美国伊利诺依大学香槟分校机械工程系,博士 教学与课程 本科生课程:材料力学(乙) 研究生课程:高等断裂力学 科研 主要采用跨尺度理论建模与数值模拟研究细胞力学与力生物学、生物材料力学、仿生力学等。 研究与成果 在小尺度下细胞与基体的相互作用、壁虎粘附等方向取得了重要成果。发现壁虎粘附三级放大功能;揭示壁虎粘附中的预应力效应;构建细胞粘附中的逆锁键动力学模型;阐述了循环载荷作用下细胞转向的准则;采用多尺度分析方法解释了骨骼肌收缩时分子马达力调控的机制;建立定量关联水凝胶力学性能与其所构成的蛋白质动力学特性的本构模型等。 研究工作以第一作者或者通讯作者发表在Nature Communications,Science Advances,Nano Letters,Annual Review of Biophysics,JMPS,Biophysical Journal等刊物。 培养一名研究生获得浙大“竺可桢”奖。 专利: Boyce,M.,Parks,D.,and Chen,B.,2008.Filler-enhanced polymeric fibers with improved mechanical properties and method for making.United States Patent.No.7,425,368. 书本章节: Chen,B.,Wu,P.D.,Xia,Z.C.,MacEwen,S.R.,Tang,S.C.,and Huang,Y.,2000.A dilatational plasticity theory for aluminum sheets.In Multiscale Deformation and Fracture in Materials and Structures.pp.17-30,Netherlands:Springer. 招生信息 课题组计划招博士后一名,研究方向为细胞力学与软物质力学 课题组计划每年招博士和硕士各一名,研究方向为生物力学与仿生、软物质力学等

研究领域

材料力学行为 生物力学与仿生 软物质力学

近期论文

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45.Li,Xi and Chen,Bin*2020 Switching cellular swirling upon one-way torsional drive J.Appl.Mech.87(7):071002. 44.Sun,Wenxu,Xue,Bin,Fan,Qiyang,Tao,Runhan,Wang,Chunxi,Wang,Xin,Li,Yiran,Qin,Men,Wang,Wei*,Chen,Bin*,and Cao,Yi*2020 Molecular engineering of metal coordination interactions for strong,tough,and fast-recovery hydrogels.Science Advances.6(16):eaaz9531. 43.Yu,Wenting,Sun,Wenxu,Fan,Qiyang,Xue,Bin Xue,Li,Yiran,Qin,Meng,Li,Ying,Chen,Bin*,Wang,Wei*,and Yi Cao*2019 Tuning of the dynamics of metal ion crosslinked hydrogels by network structures.Soft Matter.15:4423-4427. 42.Fan,Qiyang and Chen,Bin*2019 Constitutive model for the growth of a gel network regulated by its microscopic mechanics toward a homeostatic state.Journal of the Mechanics and Physics of Solids.130:181-194. 41.Wei,Jie,Chen,Xiaofeng and Chen,Bin*2019 Harnessing structural instability for cell durotaxis.Acta Mechanica Sinica.35(2):355-364. 40.Fan,Qiyang,Chen,Bin*,and Cao,Yi*2019 Constitutive model reveals the defect-dependent viscoelasticity of protein hydrogels.Journal of the Mechanics and Physics of Solids.125:653-665. 39.Dong,Chenling,Chen,Xiaofeng,and Chen,Bin*2018 Standard loading profile in matrix rigidity sensing.Biophysical Journal.114:1216-1224. 38.Wu,J.,Li,P.,Dong,C.,Jiang,H.,Xue,B.,Gao,X.,Qin,M.,Wang,W.*,Chen,B.*,and Cao Y.*,2018 Rationally designed synthetic protein hydrogels with predictable mechanical properties.Nature Communications.9:620. 37.Dong,Chenling and Chen,Bin 2017 Quantifying the bending of bilayer temperature-sensitive hydrogels.Proceedings of the Royal Society A-Mathematical Physical and Engineering Sciences 473(2200):20170092. 36.Wei,Jie,Dong,Chenling,Chen,Bin 2017 Effects of adenosine triphosphate concentration on motor force regulation during skeletal muscle contraction.Acta Mechanica Sinica 33(2):243-249. 35.Chen,Xiaofeng,Chen,Bin 2016 Simplified Analysis for the Association of a Constrained Receptor to an Oscillating Ligand.Journal of Applied Mechanics-Transactions of the ASME.,83(9):091006. 34.Dong,C.,Chen,B 2016 Coupling of bond breaking with state transition leads to high apparent detachment rates of a single Myosin.Journal of Applied Mechanics-Transactions of the ASME.83(5):051011. 33.Dong,C.and Chen,B.,2016 Temperature effect on the chemomechanical regulation of substeps within the power stroke of a single Myosin II.Scientific Reports.6:19506. 32.Dong,C.and Chen,B.2015 Catch-slip bonds can be dispensable for motor force regulation during skeletal muscle contraction.Physical Review E 92:012723. 31.Fang,J.,Chen B.,Pan,H.2015 Anomalous friction of graphene nanoribbons on waved graphenes.Theor.Appl.Mech.Lett.5(6):222-226. 30.Mao,Z.,Chen,X.,Chen B.2015 Stability of focal adhesion enhanced by its inner force fluctuation.Chin.Phys.B.24(8):088702. 29.Chen,X.,Li,D.,Ji,B.,and Chen B.2015 Reconciling bond strength of a slip bond at low loading rates with rebinding.Europhysics Letters.109(6):68002. 28.Wang,L.,Li,Y.,Chen,B.,Liu,S.,Li,M.,Zheng,L.,Wang,P.,Lu,T.J.,and Xu F.,2015 Patterning cellular alignment through stretching hydrogels with programmable strain gradients.ACS Appl.Mater.Interfaces 7(27):15088–15097. 27.Chen,B.,Chen,X.,and Gao,H.,2015 Dynamics of cellular reorientation on a substrate under biaxial cyclic stretches.Nano Letters.15(8):5525-9. 26.Chen,B.,Ji,B.,and Gao,H.,2015 Modeling active mechanosensing in cell–matrix interactions.Annual Review of Biophysics.44:1-32. 25.Chen,X.,Mao,Z.X.,and Chen,B.,2015 Probing time-dependent mechanical behaviors of catch bonds based on two-state models.Scientific reports.5:7868. 24.Chen,X.and Chen,B.,2014 Probing the instability of a cluster of slip bonds upon cyclic loads with a coupled finite element analysis and Monte Carlo method.Journal of applied mechanics-Transactions of the ASME.81(11):111002. 23.Chen,B.,and Dong,C.,2014 Modeling Deoxyribose Nucleic Acid as an elastic rod inlaid with fibrils.Journal of applied mechanics-Transactions of the ASME.81(7):071005. 22.Chen,B.,2014 Probing the effect of random adhesion energy on receptor-mediated endocytosis with a semistochastic model.Journal of applied mechanics-Transactions of the ASME.81(8):081013. 21.Pan,H.,Chen,B.,2014 Ultra-flexibility and unusual electronic,magnetic and chemical properties of waved graphenes and nanoribbons.Scientific Reports.4:4198. 20.Cheng,Y.,Pugno,N.,Shi,X.,Chen,B.,Gao,H.,2013 Surface energy-controlled self-collapse of Carbon Nanotube bundles with large and reversible volumetric deformation.Journal of applied mechanics-Transactions of the ASME.80(4):040902. 19.Chen,B.,2013 Self-regulation of motor force through chemomechanical coupling in skeletal muscle contraction.Journal of Applied Mechanics-Transactions of the ASME.80(5):051013. 18.Chen,B.,Kemkemer,R.,Deibler,M.,Spatz,J.,Gao,H.,2012 Cyclic Stretch Induces Cell Reorientation on Substrates by Destabilizing Catch Bonds in Focal Adhesions.PLoS ONE.7(11):e48346. 17.Chen,B.,2012.A shear lag analysis predicts the strong size effect on the persistence length of microtubules,Applied Physics Letters.101:093708. 16.Chen,B.and Gao,H.,2012.Are mammals ferroelectric?Physics.5:19.(Viewpoint of PRL) 15.Cheng,Q.,Chen,B.,Gao,H.,Zhang,Y.,2012.Sliding-induced non-uniform pre-tension governs robust and reversible adhesion-a revisit of adhesion mechanisms of gecko.Journal of the royal society Interface.9:283. 14.Chen,B.and Gao,H.,2011.Motor force in skeletal muscle contraction.Biophysical Journal.101:396. 13.Gao,H.,Qian,J.,and Chen,B.,2011.Probing mechanical principles of focal contacts in cell-matrix adhesion in a coupled stochastic-elastic modeling framework.Journal of the royal society Interface.8:1217. 12.Chen,B.and Gao,H.,2010.Mechanical principle of enhancing cell-substrate adhesion via pretension.Biophysical Journal.98:2154. 11.Chen,B.and Gao,H.,2010.An alternative explanation of the effect of humidity in gecko adhesion:stiffness reduction enhances adhesion on a rough surface.International Journal of Applied Mechanics.2:1. 10.Chen,B.,Wu,P.D.,and Gao,H.,2009.Geometry-and velocity-constrained cohesive zones and mixed mode fracture/adhesion energy with periodic cohesive interactions.Proceedings of Royal Society A-Mathematical Physical and Engineering Sciences.465:1043. 9.Chen,B.,Wu,P.D.,and Gao,H.,2009.A characteristic length for stress transfer in the nanostructure of biological composites.Composites Science and Technology.69:1160. 8.Chen,B.,Shi,X.H.,and Gao,H.,2008.Apparent fracture/adhesion energy of interfaces with periodic cohesive interactions.Proceedings of Royal Society A-Mathematical Physical and Engineering Sciences.464:657-671. 7.Chen,B.,Wu,P.D.,and Gao,H.,2008.Hierarchical modeling of attachment and detachment mechanisms of gecko toe adhesion.Proceedings of Royal Society A-Mathematical Physical and Engineering Sciences.464:1639-1652. 6.Chen,B.,Wu,P.D.,and Huang,Y.,2008.Detaching speed of a fibrillar interface.Applied physics letters.93:103901. 5.Chen,B.,Wu,P.D.,and Gao,H.,2008.Pre-tension generates strongly reversible adhesion of a spatula pad on substrate.Journal of the royal society Interface.6:529. 4.Chen,B.,Huang,Y.,Liu,C.,Wu,P.D.,and MacEwen,S.R.,2004.A dilatational plasticity theory for viscous materials.Mechanics of Materials.36:679. 3.Chen,B.,Huang,Y.,Gao,H.,and Wu,P.D.,2004.Shear crack propagation along weak planes in solids:a finite deformation analysis incorporating the linear harmonic potential.International Journal of Solids and Structures.41:1. 2.Chen,B.,Huang,Y.,Gao,H.,and Yang,W.,2004.On the finite opening of intersonic shear cracks.International Journal of Solids and Structures.41:2293. 1.Chen,B.,Gao,M.,Zuo,J.M.,Qu,S.,Liu,B.,and Huang,Y.,2003.Binding energy of parallel carbon nanotubes.Applied Physics Letters.83:3570.

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