当前位置: X-MOL首页全球导师 海外导师 › Chooi, Yit Heng

研究领域

Secondary metabolite biosynthesis - Fungal pathogen host-interactions - Synthetic biology

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Mao, X.M., Xu, W., Li, D., Yin, W.B., Chooi, Y.H., Li, Y.Q., Tang, Y., Hu, Y. 2015, 'Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products', ANGEWANDTE CHEMIE - INTERNATIONAL EDITION, 54, 26, pp. 7592-7596. Detail Lin, H.C., Chiou, G., Chooi, Y.H., McMahon, T.C., Xu, W., Garg, N.K., Tang, Y. 2015, 'Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids', Angewandte Chemie - International Edition, 54, pp. 3004-3007. Detail Chooi, Y.H., Krill, C., Barrow, R.A., Chen, S., Trengove, R., Oliver, R.P., Solomon, P.S. 2015, 'An In planta-expressed polyketide synthase produces (R)-mellein in the wheat pathogen Parastagonospora nodorum', APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81, 1, pp. 177-186. Detail Cacho, R.A., Tang, Y., Chooi, Y.H. 2015, 'Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi', Frontiers in Microbiology, 5, pp. 1-16. Detail Sato, M., Yagishita, F., Mino, T., Uchiyama, N., Patel, A., Chooi, Y-H., Goda, Y., Xu, W., Noguchi, H., Yamamoto, T., Hotta, K., Houk, K.N., Tang, Y., Watanabe, K. 2015, 'Involvement of lipocalin-like CghA in decalin-forming stereoselective intramolecular [4+2] cycloaddition', CHEMBIOCHEM, 16, 16, pp. 2294-2298. Detail Chooi, Y-H., Solomon, P.S. 2015, 'A chemical ecogenomics approach to understand the roles of secondary metabolites in fungal cereal pathogens', Frontiers in Microbiology, 5, pp. 1-7. Detail Tan, K.C., Phan, H.T.T., Rybak, K., John, E., Chooi, Y.H., Solomon, P.S., Oliver, R.P. 2015, 'Functional redundancy of necrotrophic effectors – consequences for exploitation for breeding', Frontiers in Plant Science, 6, JULY, pp. 1-9. Detail Chooi, Y.H., Muria-Gonzalez, M.J., Mead, O.L., Solomon, P.S. 2015, 'SnPKS19 encodes the polyketide synthase for alternariol mycotoxin biosynthesis in the wheat pathogen Parastagonospora nodorum', Applied and Environmental Microbiology, 81, 16, pp. 5309-5317. Detail Medema, M.H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J.B., Blin, K., De Bruijn, I., Chooi, Y.H., Claesen, J., Coates, R.C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D.J., Fewer, D.P., Garg, N., Geiger, C., Gomez-Escribano, J.P., Greule, A., Hadjithomas, M., Haines, A.S., Helfrich, E.J.N., Hillwig, M.L., Ishida, K., Jones, A.C., Jones, C.S., Jungmann, K., Kegler, C., Kim, H.U., Kötter, P., Krug, D., Masschelein, J., Melnik, A.V., Mantovani, S.M., Monroe, E.A., Moore, M., Moss, N., Nützmann, H.W., Pan, G., Pati, A., Petras, D., Reen, F.J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N.J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A.K., Balibar, C.J., Balskus, E.P., Barona-Gómez, F., Bechthold, A., Bode, H.B., Borriss, R., Brady, S.F., Brakhage, A.A., Caffrey, P., Cheng, Y.Q., Clardy, J., Cox, R.J., De Mot, R., Donadio, S., Donia, M.S., Van Der Donk, W.A., Dorrestein, P.C., Doyle, S., Driessen, A.J.M., Ehling-Schulz, M., Entian, K.D., Fischbach, M.A., Gerwick, L., Gerwick, W.H., Gross, H. 2015, 'Minimum Information about a Biosynthetic Gene cluster', Nature Chemical Biology, 11, 9, pp. 625-631. Detail Mao, X.M., Zhan, Z.J., Grayson, M.N., Tang, M.C., Xu, W., Li, Y.Q., Yin, W.B., Lin, H.C., Chooi, Y.H., Houk, K.N., Tang, Y. 2015, 'Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System', Journal of the American Chemical Society, 137, 37, pp. 11904-11907. Detail Yap, H.Y.Y., Chooi, Y.H., Fung, S.Y., Ng, S.T., Tan, C.S., Tan, N.H. 2015, 'Transcriptome analysis revealed highly expressed genes encoding secondary metabolite pathways and small cysteine-rich proteins in the sclerotium of lignosus rhinocerotis', PLoS ONE, 10, 11, pp. e0143549. Detail Yap, H.Y.Y., Chooi, Y.H., Firdaus-Raih, M., Fung, S.Y., Ng, S.T., Tan, C.S., Tan, N.H. 2014, 'The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties', BMC Genomics, 15, 1, pp. 1-12. Detail Chooi, Y.H., Muria-Gonzalez, M.J., Solomon, P.S. 2014, 'A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum', Mycology, 5, 3, pp. 192-206. Detail Zabala, A.O., Chooi, Y.H., Choi, M.S., Lin, H.C., Tang, Y. 2014, 'Fungal polyketide synthase product chain-length control by partnering thiohydrolase', ACS Chemical Biology, 9, 7, pp. 1576-1586. Detail Lin, H.C., Tsunematsu, Y., Dhingra, S., Xu, W., Fukutomi, M., Chooi, Y.H., Cane, D.E., Calvo, A.M., Watanabe, K., Tang, Y. 2014, 'Generation of complexity in fungal terpene biosynthesis: Discovery of a multifunctional cytochrome P450 in the fumagillin pathway', Journal of the American Chemical Society, 136, 11, pp. 4426-4436. Detail Chooi, Y.H., Hong, Y.J., Cacho, R.A., Tantillo, D.J., Tang, Y. 2013, 'A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis', Journal of the American Chemical Society, 135, 45, pp. 16805-16808. Detail Cacho, R.A., Chooi, Y.H., Zhou, H., Tang, Y. 2013, 'Complexity generation in fungal polyketide biosynthesis: A spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin', ACS Chemical Biology, 8, 10, pp. 2322-2330. Detail Yin, W.B., Chooi, Y.H., Smith, A.R., Cacho, R.A., Hu, Y., White, T.C., Tang, Y. 2013, 'Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in aspergillus nidulans', ACS Synthetic Biology, 2, 11, pp. 629-634. Detail Chooi, Y.H., Fang, J., Liu, H., Filler, S.G., Wang, P., Tang, Y. 2013, 'Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi', Organic Letters, 15, 4, pp. 780-783. Detail Xu, W., Chooi, Y.H., Choi, J.W., Li, S., Vederas, J.C., Da Silva, N.A., Tang, Y. 2013, 'LovG: The thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis', Angewandte Chemie - International Edition, 52, 25, pp. 6472-6475. Detail

推荐链接
down
wechat
bug