Arulpragasam, Ajanthy - Curtin University - School of Biomedical Sciences

研究领域

Scholarship of teaching and learning G protein-coupled receptors The calcium-sensing receptor 14-3-3 proteins

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External benchmarking of the syllabus and assessment in first year human biology, Human Structure and Function Grant body: Teaching Excellence Development Fund, Curtin University Grant period: 2015 Cluning C, Ward BK, Rea SL, Arulpragasam A, Fuller PJ and Ratajczak T (2013) The helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones. Molecular Endocrinology 27(7): 1020-1035. Arulpragasam A, Magno AL, Ingley E, Brown SJ, Conigrave AD, Ratajczak T and Ward BK (2012) The 14-3-3 adapter protein binds to the calcium-sensing receptor and attenuates calcium-sensing receptor-mediated Rho-kinase signalling. Biochemical Journal 441: 995-1006. Vukovic J, Ruitenberg MJ, Roet K, Franssen E, Arulpragasam A, Sasaki T, Verhaagen J, Harvey AR, Busfield SJ and Plant GW (2008) The glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing cells in vitro. Glia 52: 424-443. Hu Y, Arulpragasam A, Plant GW, Hendriks WTJ, Cui Q and Harvey AR (2007) The importance of transgene and cell type on the regeneration of adult retinal ganglion cell axons within reconstituted bridging grafts. Experimental Neurology 207: 314-328. Minchin RF, Knight S, Arulpragasam A and Fogel-Petrovic M (2006) Concentration dependent effects of N,N-diethylnorspermine on melanoma cell proliferation. International Journal of Cancer 118 (2): 509-512. Leaver SG, Cui Q, Plant GW, Arulpragasam A, Hisheh S, Verhaagen J and Harvey AR (2006) AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells. Gene Therapy 1-14. Butcher NJ, Arulpragasam A, Goh HL, Davey T and Minchin RF (2005) Genomic organisation of human arylamine N-Acetyltransferase type 1 reveals alternative promoters that generate different 5’-UTR splice variants with altered translational activities. Biochemical Journal 387: 119-127. Butcher NJ, Arulpragasam A and Minchin RF (2004) Proteasomal degradation of N-Acetyltransferase 1 is prevented by acetylation of the active site cysteine. Journal of Biological Chemistry 279 (21): 22131-22137. Butcher NJ, Arulpragasam A, Pope C and Minchin RF (2003) Identification of a minimal promoter sequence for the human Arylamine N-Acetyltransferase 1 gene that binds AP-1 and YY-1. Biochemical Journal 376: 441-448.