个人简介

Mark graduated Bachelor of Medicine from the University of Newcastle in 1985 and subsequently trained as a specialist endocrinologist in Australia and the UK. He completed a PhD in the endocrinology of pregnancy in 1998, and has had a research and clinical interest in hormonal function in pregnancy ever since. Mark has worked as a clinical endocrinologist in Western Sydney since 1996, as a Staff Specialist at Westmead and Blacktown-Mt Druitt Hospitals, and now as the Head of Department of Medicine at Blacktown-Mt Druitt Hospital. He has been involved in clinical teaching for more than 20 years, was Director of Physician Training at Westmead Hospital 2005-2009, and is a member of the National Examining Panel for the Royal Australasian College of Physicians. Mark is extensively involved in clinical and basic science research and his main research interest is the effect of events in pregnancy on the metabolic health of the mother and baby, with a particular emphasis on Gestational Diabetes. Additional research is being done on the "metabolic stress" that occurs during hormonal manipulation for cancer treatment, or under treatment with some psychiatric medications, and exploration of new mechanisms which might be responsible for causing type 2 diabetes. Mark also works with a team of clinicians and researchers at Blacktown who are trying to optimize the health system for management and prevention of diabetes in Western Sydney. He also has a significant clinical interest in pituitary disorders, and heads the Pituitary Clinic at Westmead Hospital. Mark is a Past-President of the Endocrine Society of Australia. In 2009 he was appointed UWS Foundation Professor of Medicine at Blacktown / Mt Druitt Clinical School and has been a significant contributor to the growth of the new Medical School, and development of Blacktown-Mt Druitt Hospital as a teaching hospital and research centre. He has been awarded 1 current, and 2 past, NH&MRC Project Grants. He has supervised 5 completed PhDs, and 3 current PhD students.

研究领域

Medicine

Diabetes management Obesity and metabolic complications of pregnancy Pituitary disorders

近期论文

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Lau, S., Muir, C., Assur, Y., Beach, R., Tran, B., Bartrop, R., McLean, M. and Caetano, D. (2016), 'Predicting weight gain in patients treated with clozapine : the role of sex, body mass index, and smoking', Journal of Clinical Psychopharmacology, vol 36, no 2 . Yap, C., Cheung, N., Gunton, J., Athayde, N., Munns, C., Duke, A. and McLean, M. (2014), 'Vitamin D supplementation and the effects on glucose metabolism during pregnancy : a randomized controlled trial', Diabetes Care, vol 37, no 7 , pp 1837 - 1844. Lind, J., Hennessy, A. and McLean, M. (2014), 'Cardiovascular disease in women : the significance of hypertension and gestational diabetes during pregnancy', Current Opinion in Cardiology, vol 29, no 5 , pp 447 - 453. Astell-Burt, T., Feng, X., Kolt, G., McLean, M. and Maberly, G. (2014), 'Understanding geographical inequities in diabetes : multilevel evidence from 114,755 adults in Sydney, Australia', Diabetes Research and Clinical Practice, vol 106, no 3 , pp 68 - 73. Padmanabhan, S., McLean, M. and Cheung, N. (2014), 'Falling insulin requirements are associated with adverse obstetric outcomes in women with preexisting diabetes', Diabetes Care, vol 37, no 10 . McLean, M., Moaven, L., Moin, N. and Bradford, J. (2013), 'Controversy grows over redefinition of gestational diabetes', Medical Journal of Australia, vol 198, no 11 , pp 596 - 597. Rae, K., Weatherall, L., Hollebone, K., Apen, K., McLean, M., Blackwell, C., Eades, S., Boulton, J., Lumbers, E. and Smith, R. (2013), 'Developing research in partnership with Aboriginal communities : strategies for improving recruitment and retention', Rural and Remote Health, vol 13, no 1 . Lau, S., Cha, K., Karunatillake, A., Stokes, R., Cheng, K., McLean, M., Cheung, N., Gonzalez, F. and Gunton, J. (2013), 'Beta-cell ARNT is required for normal glucose tolerance in murine pregnancy', PLoS One, vol 8, no 10 . Razee, H., Van Der Ploeg, H., Blignault, I., Smith, B., Bauman, A., McLean, M. and Wah Cheung, N. (2010), 'Beliefs, barriers, social support, and environmental influences related to diabetes risk behaviours among women with a history of gestational diabetes', Health Promotion Journal of Australia, vol 21, no 2 , pp 130 - 137. Carmen Wong, K., Wong, V., Ho, J., Torpy, D., McLean, M. and Cheung, N. (2010), 'High cortisol levels in hyperglycaemic myocardial infarct patients signify stress hyperglycaemia and predict subsequent normalization of glucose tolerance', Clinical Endocrinology, vol 72, no 2 , pp 189 - 195. Gan, R., Wong, V., Cheung, N. and McLean, M. (2009), 'Effect of insulin infusion on electrocardiographic findings following acute myocardial infarction : importance of glycaemic control', Diabetic Medicine, vol 26 , pp 174 - 176. Zehle, K., Smith, B., Chey, T., McLean, M., Bauman, A. and Cheng, N. (2008), 'Psychosocial factors related to diet among women with recent gestational diabetes opportunities for intervention', Diabetes Educator, vol 34, no 5 , pp 807 - 814. Cheung, N., Wong, V. and McLean, M. (2008), 'What glucose target should we aim for in myocardial infarction?', Diabetes Research and Clinical Practice, vol 80, no 3 , pp 411 - 415. Maguire, A., Biesheuvel, C., Ambler, G., Moore, B., McLean, M. and Cowell, C. (2008), 'Evaluation of adrenal function using the human corticotrophin-releasing hormone test, low dose Synacthen test and 9am cortisol level in children and adolescents with central adrenal insufficiency', Clinical Endocrinology, vol 68, no 5 , pp 683 - 691. Ramachenderan, J., Bradford, J. and McLean, M. (2008), 'Maternal obesity and pregnancy complications : a review', Australian and New Zealand Journal of Obstetrics and Gynaecology, vol 48, no 3 , pp 228 - 235. Schneider, H., Goodall, I., Coleman, P., McLean, M. and Barker, G. (2007), 'The new haemoglobin A1c: The way it is reported is about to change...', Internal Medicine Journal, vol 37 , pp 213 - 215.