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个人简介

余海中,男,安徽铜陵人,2018年毕业于安徽农业大学生命科学学院生物化学与分子生物学专业,获博士学位,先后参与完成国家863项目子课题1项,国家自然科学基金面上项目2项。目前主持江西省教育厅重点项目1项。主要承担本科《分子生物学》和《基础生物化学》和研究生《高级分子生物学》教学工作。   课题研究主要涉及到的技术:NMR核磁共振、iTRAQ定量蛋白质组学、RNA-seq转录组学,RNA干扰、免疫荧光、蛋白质Pull-down、昆虫SF9细胞培养和昆虫CRISPR-Cas9基因敲除技术等。真心希望对昆虫研究有着浓厚的兴趣,熟悉以上技术的本科生和研究生加入本课题组。   主持及参与项目:   1.Toll信号通路介导的组织蛋白酶L和O在柑橘木虱先天性免疫中的分子机制,江西省教育厅重点项目,2019/01-2021/12,5万,在研,主持。   2.赣州市科技创新人才项目,柑橘木虱几丁质合成途径中海藻糖抑制剂的筛选及其在木虱防控中的应用,2020/01-2022/12,在研,主持。   3.CLas病菌侵染柑橘木虱中肠及其调控UPS免疫逃避机制研究,国家自然科学基金地区项目,2020/01-2023/12,40万,在研,参与。   4.BmNPV与宿主家蚕中肠及胞内蛋白互作的分子机制研究,国家自然科学基金面上项目,2014/01-2018/12,80万,结题,参与。      

研究领域

主要研究方向包括柑橘木虱生长发育关键基因的鉴定及功能、柑橘木虱抗药性机制、柑橘木虱先天性免疫、柑橘木虱与柑橘黄龙病互作和斜纹夜蛾先天性免疫。

近期论文

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1.Hai-Zhong Yu, Yu-Ling Huang, Zhan-Jun Lu*, et al. Inhibition of trehalase affects the trehalose and chitin metabolism pathway in Diaphorina citri (Hemiptera: Psyllidae). Insect Science, 2020, Accept (SCI中科院大区1区top, IF: 2.71).   2.Hai-Zhong Yu, Ning-Yan Li, Bing Li, et al. Immune functional analysis of chitin deacetylase 3 from the Asian citrus psyllid Diaphorina citri. International Journal of Molecular Sciences, 2020, 21, 64 (IF: 4.183).   3.Hai-Zhong Yu, Ning-Yan Li, Xiang-Dong Zeng, et al. Transcriptome analysis of Diaphorina citri midgut responses to Candidatus Liberibacter asiaticus infection. Insects, 2020, 11, 171. (IF: 2.139)   4.Hai-Zhong Yu, Ning-Yan Li, Yan-Xin Xie, et al. Identification and functional analysis of two chitin synthase genes in the common cutworm, Spodoptera litura, Insects, 2020, 11, 253. (IF: 2.139)   5.Hai-Zhong Yu, Yu-Ling Huang, Ning-Yan Li, et al. Potential roles of two Cathepsins genes, DcCath-L and DcCath-O in the innate immune response of Diaphorina citri. Journal of Asia-Pacific Entomology, 2019, 22: 1060-1069. (IF: 0.967)   6.Hai-Zhong Yu, Jie Wang, Shang-Zhi Zhang, et al. Molecular characterization of Apolipophorin-Ⅲ gene in Samia cynthia ricini and its roles in response to bacterial infection. Journal of Invertebrate Pathology, 2018, 159, 6170. (IF: 2.101)   7.Hai-Zhong Yu, Yan Ma, Shang-Zhi Zhang, et al. Comparative transcriptome analysis of ATP-binding cassette (ABC) transporter genes in eri-silkworm, Samia cynthia ricini in response to 1-deoxynojirimycin, Journal of Asia-Pacific Entomology, 2018: 168-178. (IF: 0.967)   8.Hai-Zhong Yu, Xue-Yang Wang, Jia-Ping Xu, et al. iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains, Journal of Proteomics, 2017, 165, 35–50. (IF: 3.537, 他引26次)   9.Hai-Zhong Yu, Shang-Zhi Zhang, Yan Ma, et al. Molecular Characterization and Functional Analysis of a Ferritin Heavy Chain Subunit from the Eri-Silkworm, Samia cynthia ricini, International Journal of Molecular Sciences, 2017 (IF: 4.183).   10.Hai-Zhong Yu, Jia-Ping Yu, Xue-Yang Wang, et al. Identification of four ATP-binding cassette transporter genes in Cnaphorina medinalis and their expression in response to insecticide treatment, Journal of Insect Science, 2017, 17, 1-8. (IF: 1.446)   11.Hai-Zhong Yu, Ming-Hui Liu, Xue-Yang Wang, et al. Identification and expression profiles of chitin deacetylases genes in the rice leaf folder, Cnaphorina medinalis, Journal of Asia-Pacific Entomology, 2016, 19: 691-696. (IF: 0.967)   12.Hai-Zhong Yu, De-Fu Wen, Wan-Lin Wang, et al. Identification of genes putatively involved in Chitin Metabolism and Insecticide Detoxification in the rice leaf folder (Cnaphalocrocis medinalis) larvae through transcriptome analysis, International Journal of Molecular Sciences, 2015, 16, 21873-21896. (IF: 4.183)   13.Zhan-Jun Lu, Yu-Ling Huang, Hai-Zhong Yu*, et al. Silencing of the Chitin Synthase Gene Is Lethal to the Asian Citrus Psyllid, Diaphorina citri, International Journal of Molecular Sciences, 2019, 20, 3734 (通讯作者, IF: 4.183)   14.Zhan-Jun Lu, Hai-Zhong Yu, Lan-Fang Mi, et al. The effects of inarching Citrus reticular Blanco var. tangerine on the tree vigor, nutrient status and fruit quality of Citrus sinensis Osbeck ‘Newhall’ trees that have Poncirus trifoliata (L.) Raf. as rootstocks. Scientia Horticulturae, 2019, 256, 108600 (共同一作, IF: 1.961)   15.Zhan-Jun Lu, Yan-Xin Xie, Hai-Zhong Yu*, et al. Identification of an iron binding protein, ferritin heavy chain subunit and functional analysis, from swallowtail butterfly, Papilio xuthus. Archives of Insect Biochemistry & Physiology, 2019, 102, 1 (通讯作者, IF: 1.198)   16.Zhan-Jun Lu, Cheng-Hua Zhou, Hai-Zhong Yu*, et al. Potential roles of insect Tropomyosin1-X1 isoform in the process of Candidatus Liberibacter asiaticus infection of Diaphorina citri, Journal of Insect Physiology, 2019, 114, 125-135 (通讯作者, IF: 2.862)   17.Dong-Qiong Fei, Hai-Zhong Yu, Jia-Ping Xu, et al. Isolation of ferritin and its interaction with BmNPV in the silkworm, Bombyx mori, Developmental and Comparative Immunology, 2018, 130-137 (Co-first author). (共同一作, IF: 3.119)   18.Bing Li, Hai-Zhong Yu, Chong-Jun Ye, et al. Bombyx mori Seripin6 regulates prophenoloxidase activity and the expression of antimicrobial proteins, Gene, 2017, 610, 64-70 (Co-first author). (共同一作,IF: 2.638)   19.Xue-Yang Wang, Hai-Zhong Yu, Lei Geng, et al. Comparative transcriptome analysis of Bombyx mori (Lepidoptera) Larval midgut response to BmNPV in susceptible and near-isogenic resistant strains, PLoS One, 11, e0155341 (共同一作,IF: 2.776).   20.Shang-Zhi Zhang, Hai-Zhong Yu, Ming-Jie Deng, et al. Comparative transcriptome analysis reveals significant metabolic alterations in eri-silkworm (Samia cynthia ricini) haemolymph in response to 1-deoxynojirimycin, PLoS One, 2018, 13, e0191080 (共同一作, IF: 2.776)   21.Xue-Yang Wang, Hai-Zhong Yu, Jia-Ping Xu, et al. Comparative subcellular proteomics analysis of susceptible and near-isogenic resistant Bombyx mori (Lepidoptera) larval midgut response to BmNPV infection, Scientific Reports, 7, 45690. (IF: 4.011).

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