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Representative research articles as corresponding author *
1.Gong N. et al. Liang X.-J.* Carbon dot-supported atomically-dispersed gold (CAT-g) as a mitochondrial oxidative stress amplifier for cancer treatment. Nature Nanotechnology. 2018. DOI: 10.1038/s41565-019-0373-6 (in press)
2.Zhang T, et al. Liang XJ* Fluorinated Oligoethylenimine Nanoassemblies for Efficient siRNA-Mediated Gene Silencing in Serum-Containing Media by Effective Endosomal Escape. Nano Letter. 2018. 18(10):6301-6311.
3.Zhao Y, et al. Liang XJ*. Spatiotemporally Controllable Peptide-based Nanoassembly in Single Living Cells for a Biological Self-portrait. Advanced Materials 2017. 29,1601128.
4.Xue, X.; et al. Liang, X. J*. Aggregated single-walled carbon nanotubes attenuate the behavioural and neurochemical effects of methamphetamine in mice. Nature Nanotechnology 2016, 11 (7), 613-620.
5.Wei, T.; et al. Liang, X.J*. Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance. PNAS. (Proc Natl Acad Sci U S A.). 2015. 112 (10): 2978-2983.
6.Xue, X.; et al. Liang, X. J*. Single-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's disease. Nano Letters 2014, 14 (9), 5110-5117.
7.Xue, X.; et al. Liang, X. J*. Spatiotemporal drug release visualized through a drug delivery system with tunable aggregation-induced emission. Advanced Materials 2014, 26 (5), 712-7.
8.Wei, T.; et al. Liang, X. J.* Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo. Nano Letters 2013, 13 (6), 2528-34.
9.Huo, SD.; et al. Liang, X. J.* Superior penetration and retention behavior of 50nm gold nanoparticles in tumor. Cancer Research. 2013 73:319-330.
10.Liang, X.J. * et al. Metallofullerene Nanoparticles Circumvent Tumor Resistance to Cisplatin by Reactivating Endocytosis. PNAS. (Proc Natl Acad Sci U S A.). 2010. 107(16):7449-7454.
Representative review articles as corresponding author *:
1.Yufei Wang, Yuxuan Zhang, Jinjin Wang, Xing-Jie Liang*. AIE fluorophores as imaging tools to explore biological fate of nano-drug delivery systems. Advanced Drug Delivery Review. DOI：10.1016/j.addr.2018.12.004. (In press)
2.Ningqiang Gong; Yuxuan Zhang; Zhen Zhang; Xianlei Li; Xing-Jie Liang*. Functional Nanomaterials Optimized to Circumvent Tumor Immunological Tolerance. Advanced Functional Materials. 2018. 1806087 (1-16)
3.Xiao-Li Liu, Shizhu Chen, Huan Zhang, Jin Zhou, Hai-Ming Fan* and Xing-Jie Liang* Magnetic Nanomaterials for Advanced Regenerative Medicine: The Promise and Challenges. Advanced Materials. 2018. 12(4): e 1804922.
4.Yuxuan Zhang, Yufei Wang, Jinjin Wang and Xing-Jie Liang*. Pharmaceutical Research and Development Improved with AIE-based Nanostructures. Materials Horizons, 2018, 5, 799 – 812.
5.Yufei Wang, Juan Liu, Xiaowei Ma and Xing-Jie Liang* Nanomaterial-assisted sensitization of oncotherapy. Nano Research 2018. 11(6): 2932–2950.
6.Lu Liu, Weisheng Guo, Xing-Jie Liang*. Move to Nano-Arthrology: Targeted Stimuli-Responsive Nanomedicines Combat Adaptive Treatment Tolerance (ATT) of Rheumatoid Arthritis. Biotechnology Journal. 2018. 1800024 (1-14).
7.Yifeng Wang , Lu Liu , Xue Xue , Xing-Jie Liang*. Nanoparticle-based drug delivery systems: What can they really do in vivo? F1000 Research. 2017. 6 (F1000 Faculty Rev):681 (doi: 10.12688/f1000research.9690.1)
8.Xiaowei Ma, Ningqiang Gong, Lin Zhong, Xing-Jie Liang *. Future of Nanotherapeutics: Targeting the Cellular Sub-organelles. Biomaterials. 2016. 97: 10-21.
9.Juan Liu, Yuran Huang, Anil Kumar, Aaron Tan, Shubin Jin, Anbu Mozhi, Xing-Jie Liang*. pH-Sensitive nano-systems for drug delivery in cancer therapy. Biotechnology Advances 2014.32(4): 693-710.
10.Xiao-wei Ma, Yuliang, Zhao, Xing-Jie Liang*. Theranostic Nanoparticles engineered for Clinic and Pharmaceutics. Accounts of Chemical Research. 2011. 44(10): 1114–1122
Representative articles before working at nanocenter：
1.Liang, X. J.*, Shen, D.W., Yin, J.J., Aszalos, A., and Gottesman, M. M. SIRT1 contributes to cisplatin resistance in cancer cells by altering mitochondrial metabolism. Molecular Cancer Research. 2008, 6(9):1499-1506.
2.Liang, X.J., Choi, Y., Sackett, D.L. and Park, J.K. Inhibition of stathmin enhances CCNU blocking glioma cell migration and invasion. Cancer Research. 2008, 68(13):5267-5272.
3.Hall MD, Okabe M, Shen, DW, Liang, XJ, and Gottesman, MM. The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy. Annual Review of Pharmacology and Toxicology. 2008，48: 495-535.
4.Ngo.T.B*, Peng T., *, Liang X.J *., Akeju O., Pastorino S., Zhang W., Fine H.A., Maric D., Wen P.Y., Girolami U.D., Black P.M., Wu W., Shen R.F., Kang D.W., and Park J.K. The 1p encoded protein stathmin modulates the response of malignant gliomas to nitrosoureas. Journal of National Cancer Institute. 2007, 99: 639-652.
5.Liang, X. J., Mukherjee, S., Shen, D. W., Maxfield, F. R. and Gottesman, M. M. Endocytic Recycling Compartments Altered in Cisplatin-Resistant Cancer Cells . Cancer Research. 2006, 66 (4): Feb 15; 2346-2353.
6.Liang, X. J., Shen, D. W., Chen G. K., Wincovitch S. M., Garfield, S., and Gottesman, M. M. Trafficking and localization of platinum complexes in cisplatin-resistant cell lines monitored by fluorescence-labeled platinum. Journal of Cellular Physiology. 2005, 202 (3): 635-641.
7.Liang, X.J, Shen, D.W, and Gottesman, M.M. Down-regulation and altered localization of g-catenin in cisplatin-resistant adenocarcinoma cells. Molecular Pharmacology. 2004 65 (5): 1217-1224.
8.Liang, X.J, Shen, D.W, and Gottesman, M.M. A pleiotropic defect reducing drug accumulation in cisplatin-resistant cells. Journal of Inorganic Biochemistry. 2004 (98) 1599-1606.
9.Liang, X.J, Yin, J.J., Zhou, J.W., Wang, P. C., Taylor, B., Cardarelli, C., Kozar, M, Forte, R., Aszalos, A. and Gottesman, M. M. Changes in biophysical parameters of plasma membranes influence cisplatin resistance of sensitive and resistant epidermal carcinoma cells. Experimental Cell Research. 2004, 293: 283-291.
10.Liang, X. J., Shen, D. W., Garfield, S., and Gottesman, M. M. Mislocalization of membrane proteins associated with multidrug resistance in cisplatin-resistanct cancer cell lines. Cancer Research. 2003, 63: 5909-5916.
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