廖苍松 - 中国科学院上海药物研究所 -

个人简介

教育经历 2001.9-2005.6 中国药科大学制药工程专业工学学士 2008.9-2013.6 中科院上海药物研究所药物化学理学博士工作经历 2005.7-2007.8 浙江海正药业股份有限公司研究助理 2013.7-2014.11 中科院上海药物研究所助理研究员 2014.11-2019.12 巴塞尔大学化学系生物有机化学博士后 2020.1至今中国科学院上海药物研究所课题组长研究员

研究领域

新颖活性天然产物发现与生物催化级联反应研究

近期论文

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1. Liao C.; Seebeck F.P. *. S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reactions. Nature Catalysis. 2019, 2, 696 - 701. Highlighted by Nature Catalysis News and Views (Nature Catalysis. 2019, 2, 644 - 645) 2. Liao C.; Seebeck F.P. *. In vitro Reconstitution of Bacterial DMSP Biosynthesis. Angew. Chem. Int. Ed. 2019, 58, 3553 - 3556. 3. Goncharenko, K.V.; Flückiger S.; Liao C.; Lim, D.; Stampfli A.R.; Seebeck, F. P*. Selenocysteine as a substrate, an inhibitor and a mechanistic probe for bacterial and fungal iron‐dependent sulfoxide synthases. Chemistry-A European Journal. 2019, in press. 4. Liao C.; Seebeck F.P. *. Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria. Chembiochem. 2017, 18, 2115 - 2118. 5. Liao C.; Tang C-P.; Yao S.; Ye Y.*. Humulane-type sesquiterpenoids from Pilea cavaleriei subsp. crenata. 2013, Org. Biomol. Chem., 11, 4840-4846 6. Gamage A.M.; Liao C.; Cheah I.K.; Chen Y.; Lim D.R.X.; Ku J.W.K.; Chee R.S.L.; Gengenbacher M.; Seebeck F.P.; Halliwell B.; Gan Y.H*. The Proteobacterial Species Burkholderia Pseudomallei Produces Ergothioneine, which Enhances Virulence in Mammalian Infection. FASFEB J. 2018, 6395 - 6409. 7. Ruan J.; Liao C.; Ye Y.; Lin G*. Lack of Metabolic Activation of Predominant Formation of an Excreted Metabolite of Nontoxic Platynecine-Type Pyrrolizidine Alkaloids. Chem. Res. Toxcicol. 2014, 27, 7 - 16.