胡耀中 - 南开大学

个人简介

教育经历 2014.09-2018.01比利时布鲁塞尔自由大学，生物工程科学专业，博士学位 2013.09-2017.12天津大学，制药工程专业，博士学位 2010.09-2013.07天津大学，生物化工专业，硕士学位 2005.09-2009.07天津大学，生物工程专业，本科学位工作经历 2018.7-至今南开大学医学院，讲师荣誉和奖励 2017年，布鲁塞尔自由大学博士奖学金 2012年，硕士研究生国家奖学金

研究领域

1.小分子抗体药物的研究与开发 2.免疫学及肿瘤的免疫治疗 3.肠道微生物与机体紊乱之间的关系研究

近期论文

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HuY,LiuC,MuyldermansS.Nanobody-baseddeliverysystemsfordiagnosisandtargetedtumortherapy.FrontiersinImmunology,2017,8:1442. HuY,RomãoE,VertommenD,VinckeC,Morales-YánezF,GutiérrezC,LiuC,MuyldermansS.GenerationofNanobodiesagainstSlyDanddevelopmentoftoolstoeliminatethisbacterialcontaminantfromrecombinantproteins.ProteinExpressionandPurification,2017,137:64-76. HuY,LiuJ,HuangH.RecentagentstargetingHIF-1alphaforcancertherapy.JournalofCellularBiochemistry.2013,114:498-509. CawezF,DurayE,HuY,VandenameeleJ,RomãoE,VinckeC,GalleniM,MuyldermansS,VandevenneM.CombinatorialdesignofananobodythatspecificallytargetsstructuredRNAs.JournalofMolecularBiology,2018,11:1652-1670. RomãoE,Morales-YánezF,HuY,CrauwelsM,DePauwP,HassanzadehGG,DevoogdtN,AckaertC,VinckeC,MuyldermansS.Identificationofusefulnanobodiesbyphagedisplayofimmunesingledomainlibrariesderivedfromcamelidheavychainantibodies.CurrentPharmaceuticalDesign,2016,22:6500-6518. LiM,FanX,LiuJ,HuY,HuangH.Selectionbyphagedisplayofnanobodiesdirectedagainsthypoxiainduciblefactor-1alpha(HIF-1alpha).AppliedBiochemistryandBiotechnology,2015,62:738-745. HuangH,SongC,YangZ,DongY,HuY,GaoF.IdentificationofthereplicationoriginsfromCyanotheceATCC51142andtheirinteractionswiththeDnaAprotein:frominsilicotoinvitrostudies.FrontiersinMicrobiology,2015,6:1370. FanX,HuY,HuangH.Nanobodies:Novelbiomedicalvehiclesintargetingtumor.JournalofChemicalandPharmaceuticalResearch,2014,6:458-462.